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triteritzyBiotechnology

Dec 14, 2012 (4 years and 7 months ago)

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Devil of a Disease

Case Study Slides

2012

Goals for the Day

1.
Put the ideas of the theory of
Evolution by Natural selection to
work.

2.
Be able to write a testable
hypothesis & experiment to go along
with it.

3.
Understand the importance of
genetic variability

Question of the Day

What needs to be present in a
population for evolution by natural
selection to occur?


Hint: We talked about ways we
increase & decrease this

Case
Study:

Devil
of a Disease



Devil
of a Disease

Part I



Devil
of a Disease

Part I



Immune System


Self vs. Non
-
self



Goals for the Day

1.
Be able to evaluate possible
consequences of different
conservation actions for species.

2.
Put the ideas of the theory of
Evolution by Natural selection to
work.

3.
Understand and be able to describe
the importance of genetic variability

Question of the Day

If natural selection needs variation to
act on, what is the problem with
genetically similar individuals.

Genetic Diversity


Genetic Drift


changes in the frequency of
a gene in a population due not to mutation
or natural selection, but due to chance.



Founder effect


small numbers of
individuals are isolated from a larger
population

Genetic Diversity

Population/Genetic
Bottleneck


an
evolutionary

event in
which a significant
percentage of a population or
species is killed or otherwise
prevented from reproducing,
and the population is
reduced by 50% or more,
often by several
orders of
magnitude
.

Genetic Diversity

Population/Genetic
Bottleneck


Population
bottlenecks
increase
genetic drift
,
due to
reduction in population size.


They
also increase
inbreeding

due to the
reduced pool of possible
mates

Case
Study:

Devil
of a Disease


Part III Proposals

1.
Genetic Engineering

2.
Separate devils with tumors

3.
Find a cure

4.
Breed healthy or sick individuals in
captivity

5.
Semi
-
wild fenced off enclosures for
populations

6.
Kills devils with tumors


Part III Proposals

1.
Genetic Engineering


Pros


Cons


Part III Proposals

2.
Separate devils with tumors


Pros


Cons


Part III Proposals

3. Find a cure


Pros


Cons


Part III Proposals

4. Breed healthy or sick individuals in
captivity


Pros


Cons


Part III Proposals

5. Semi
-
wild fenced off enclosures for
populations


Pros


Cons


Part III Proposals

6. Kill devils with tumors


Pros


Cons


You are the manager! Write a
½ page explanation of which
strategy or combination of
strategies you would employ
and why.

1.
Genetic Engineering

2.
Separate devils with tumors

3.
Find a cure

4.
Breed healthy or sick individuals in captivity

5.
Semi
-
wild fenced off enclosures for populations

6.
Kills devils with tumors