Part I: LANGUAGE - The University of Lahore

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Feb 20, 2013 (4 years and 3 months ago)

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IMBB,UOL

INSTITUTE OF MOLECULAR BIOLOGY & BIOTECHNOLOGY

THE UNIVERSITY OF LAHORE

Sample Test for M.Phil/M.Phil leading to Ph.D/Ph.D

(Biochemistry/Molecular
Biology/Biotechnology/Microbiology
/Physiology)


(Fall, 2011)

Name:_______________


Roll. No.______________

Total marks: 50




Time Allowed: 1 Hr.

Part I: LANGUAGE

A.

.
In each of the following questions, pick the one most nearly opposite in meaning

1.

Ensue

a)

Liti
gate

b)

Precede

c)

Arbitrate

d)

Accentuate

e)

Delay

2.

Incongruous

a)

Geometric

b)

Prudent

c)

Legitimate

d)

Harmonious

e)

Efficacious

3.

Apostate

a)

Laggard

b)

Loyalist

c)

Martinet

d)

Predecessor

e)

Skeptic

4.

Revile

a)

Compose

b)

Awake

c)

Deaden

d)

Praise

e)

Secrete




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B.

For each blank, pick the word or set of words that
best reflects the sentence’s meaning.


5.

Slender is like counterfeit money: many people who would not coin it
__________________________ without qualms.

a)

Waste

b)

Denounce

c)

Circulate

d)

Withdraw

e)

Invest

6.

Book publishing has long been _______________________ profession
, partly because,
for younger editors, the best way to win a raise or a promotion was to move on to
another publishing house.

a)

An innovative

b)

A prestigious

c)

An itinerant

d)

A rewarding

e)

An insular

7.

For centuries, physicist have had good reason to believe in the pr
inciple of equivalence
propounded by Galileo: it has _____________________________ many rigorous tests
that _________________________ its accuracy to extraordinary precision.

a)

Endured..........compromised

b)

Passed………….presupposed

c)

Borne…………..postulated

d)

Survive
d………proved

e)

Inspired……….equated

8.

Among contemporary writers of fiction, Virginia Woolf is ____________________
figure, in some ways as radical as James Joyce, in others no more modern than Jane
Austen.

a)

A doctrinaire

b)

An introspective

c)

A peripheral

d)

A
disinterested

e)

An anomalous

Part II:LOGIC

9.

What is the sum of the product and quotient of 8 and 8?

a)

16

b)

17

c)

63

d)

64

e)

65




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10.

If the sum of three consecutive integers is less than75, what is the greatest possible
value of the smallest one?

a)

23

b)

24

c)

25

d)

26

e)

27

11.

If 25 % of 2
60 equals 6.5 % of A, what is A?

a)

10

b)

65

c)

100

d)

130

e)

1000

12.

The average of 5,10,15 and Z is 20. What is Z?

a)

0

b)

20

c)

25

d)

45

e)

50

13.

If 3
a

X 3
b

= 3
100

what is the average of a and b

a)

25

b)

45

c)

50

d)

75

e)

100

Part III: SCIENTIFIC

18. A gene always encodes a protein product.


(a)True (b) False


19. during transcription:



(a) Nucleotides are polymerized by DNA polymerase

(b) Initiation occurs at a site recognized by the sigma factor

(c) Only single gene
-
sized mRNA molecules are synthesized (d) both DNA strands of a single gene
are used as templates simultaneously

(e) Thymine in RNA pairs with adenine in DNA

20. The proofreading of newly synthesized DNA, to excise incorrect nucleotide
s which have been
inserted, is done by:


(a) a restriction endonucleases


(b) DNA gyrase



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(c) DNA ligase


(d) DNA polymerase III

(e) All of the above may participate

21. Promoter regions are nucleotide sequences that:

(a) Are involved in the initiation o
f transcription

(b) Are involved in transcription termination

(c) Contain the code for 1mRNA molecule

(d) Are important to the translation process (e) all of the above

22. The codon is found in:

(a)DNA


(b)rRNA

(c)tRNA

(d)mRNA

(e) protein

23
. In Mic
haelis
-
Menten equation, the substrate concentration at which initial velocity is equal to half of
the maximum velocity is called

a.

K
d

b.

K
m

c.

V
º

d.

K
cat

e.

K
i

24
. Rate constant which defines the number of substrate molecules converted to product in a given unit
of time

on a single enzyme molecule when enzyme is saturated with substrate is called

a.

K
d

b.

K
m

c.

K
a

d.

K
cat

25
. The best way to compare the catalytic efficiencies of different enzymes or the turnover of different
substrates by the same enzyme can be done by comparing

a.

Spe
cificity constant

b.

Dissociation constant

c.

Association constant

d.

Michaelis
-
Menton constant

e.

None of the above

26
. Alpha helical content of proteins is best determined by which of the following

a.

UV
-
VIS spectroscopy

b.

Ultracentrifugation

c.

Fluorescence spectroscopy



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d.

Circular dichroism

e.

C and D

27
. ______ play an important role as precursor of bacterial cell wall synthesis.

a.

Sugar Nucleotides

b.

Lipid bilayers

c.

Cellulose

d.

Histone proteins

e.

Gulonolactone oxidase

28
. Two families of monosaccharides are ____________.

A.

Alpha and be
ta sheets

B.

Hydrophobic and hydrophilic

C.

Aldoses and ketoses

D.

Deoxyriboses and riboses

E.

Hydroxyls and Carboxyls


29
. Two sugars that differ only in the configuration around one carbon atom are
called_______________.

A.

Monomers

B.

Epimers

C.

Dimers

D.

Homomers

E.

Hemimers


30
. In describing disaccharides or polysaccharides, the end of a chain with a free anomeric carbon is
commonly called the _____________.

A.

Oxidizing end

B.

Reducing end

C.

Oxidizing and Reducing end

D.

Caroxyl end

E.

Amino end


31
. Sphingolipids

contain a polar head group and two nonpolar tails, but unlike glycerophospholipids
they contain no ______________.

A.

Lipid A molecule

B.

Glycerol

C.

Amino Alcohol

D.

Long chain fatty acid

E.

Glycosidic linkage


32
. The _________ of DNA is most stable structure for a r
andom sequence DNA molecular under
physiological conditions.

A.

A form

B.

B form



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C.

A and B form

D.

H form

E.

Z form


33
. The H
-
DNA structure features the _________ stranded form.

A.

Single

B.

Double

C.

Triple

D.

Single or double

E.

None of the above


34
. Cholesterol is made from
___________ in four stages

A.

Acetyl
-
CoA

B.

Liposomes

C.

Glycerol

D.

B and C

E.

None of the above


35
. The first stage in cholesterol biosynthesis leads to the intermediate _________.

A.

Naysite

B.

Mevalonate

C.

Pemtivate

D.

Phosphate

E.

Pyruvate