Bioinformatics I - BIOTEC - Biotechnology Center TU Dresden

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Oct 2, 2013 (3 years and 9 months ago)

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Michael Schroeder



BioTechnological Center

TU Dresden

Biotec

Bioinformatics I

By Michael Schroeder, Biotec






2

Bioinformatics

BIO
logy

mathe
MATICS

INFOR
matics

By Michael Schroeder, Biotec






3

Bioinformatics

Bioinformatics = Biological + Informatics
-

Logical

By Michael Schroeder, Biotec






4

How to teach bioinformatics


Applied bioinformatics


Use bioinformatics tools to answer biological questions


Programming for bioinformatics


Learn how to use databases and how to programme in
Python




Term 3: Structural and computational biology

By Michael Schroeder, Biotec






5

Structure of module


Overview


A bit of everything


A web tour:


online resources for DNA and protein sequences, protein structures and
expression data


Sequence comparison


Dot plots


Dynamic programming


Substitution matrices


Multiple alignments


BLAST


PSI
-
BLAST


Phylogeny


Protein structure

By Michael Schroeder, Biotec






6

Practicals


Two types:



Bio: You

ll be given a biological questions and you

ll use online
resource to answer the question



Computing: You learn about Unix and Python, however you need
to teach yourself, too. Please buy a Python book



Each week you work through some questions during the lab and
do some homework




Simone Daminelli



By Michael Schroeder, Biotec






7

Assessment


Written exam counting 80% of final mark


Practicals: Test during lab (week 10) and homework counting
20%


Test: Will involve using online tools and resources to answer
some questions


Homework: you must pass at least 10 homework assignments
(there will be 13 overall). Passing means that >50% of your
answers are correct


For homework you get pass/fail


For the test you get a mark given that your homework is pass



Strategy for preparation


Buy book


Read book


Follow slides


Do all labs and homework



By Michael Schroeder, Biotec






8

Getting in touch

Email: ms@biotec.tu
-
dresden.de


Web site: http://www.biotec.tu
-
dresden.de/schroeder


Includes web site for bioinformatics modules

By Michael Schroeder, Biotec






9

Modules text book


Chapter 1 is online at the
module web site