Carol
Seemueller
and Katherine Kiwimagi
Ideas for GK
-
12 and Rocky
Mountain High School
Big Picture Outline
Anatomy and
Physiology
Lessons
New/Enhanced
LabQuest
labs
Bioinformatics/Tissue unit
Kinesthetic Activity/NMJ
Biology
Beetle Project (early
detection)
Introduce
LabQuest
AP Biology (next semester)
Collaboration with Slovenia
(Phages and Bioinformatics)
Micro lessons that
incorporate visualization
software of molecular
interactions
Regulation of cell cycle
Game/activity
Short presentation of
current research involving
regulation factors
Anatomy and Physiology: Lab Quest Micro
Lessons
http://upload.wikimedia.org/wikipedia/commons/4/46/DNA_Repair.jpg
Objective:
Emphasizing the connection between math, technology
and human physiology
Our Plan:
Develop micro lessons that integrate these concepts
1)
Grip strength lab (student write a hypothesis for muscle
fatigue
---
go to literature we provide to see what scientists
today think)
2)
Skin temperature lab (micro lesson that connects rate to slope
using students collected data)
Anatomy and Physiology: Introduce
Bioinformatics
Objective: Introduce bioinformatics while
studying tissues
Our Plan:
Find a Clinical Study related to a tissue defect caused by
genetics
Develop a lesson that has students use bioinformatics
software such as BLAST to help solve or better understand
the Clinical Case
Anatomy and Physiology: Model a
Neural Muscular Junction
Objective:
Students will increase their understanding of the
neuromuscular junction through a kinesthetic activity.
Our Plan:
Introduce the Neuromuscular Junction
Students will build a model of the neuromuscular
junction that reflects the relationship between form,
function, and cell communication
Anatomy and Physiology: Develop a
VO
2
max lab using lab quest
Objective:
To develop a new VO
2
max lab for the
LabQuest technology
To have students apply their knowledge of math to
the data they collect
Our Plan:
Find a contact in the Exercise and Sports Science
Department at CSU that would give a tour to
students and talk about VO
2
max
Develop lab that has student calculate their own
VO
2
max
Anatomy and Physiology: Expand on the
students understanding of
Bioinfomatics
Objective: Using bioinformatics software,
connect the dots between DNA and Cell signaling
Our Plan:
Find a Clinical Study related to a cell signaling defect
caused by genetics (Cystic Fibrosis / Asthma…)
Develop a Micro lesson that has students use
bioinformatics software such as BLAST to help solve and
better understand the Clinical Case
Anatomy and Physiology: Other Ideas
Possible collaboration
about testing the
characteristics of Bone
Design an EMG controlled Device
Biology: Beetle Project
Objectives:
“connect the dots”
relating rates of infestation “math to ecology”
To see the interdependence of science
Math, Engineering, Chemistry, Biology
State standards #2 and #9
Introduce the Niche concept
Brief introduction of Evolution
(golden toad article extinction/adaptation)
Application of the scientific method
Experiment design, Data analysis and Presentation
Biology: Beetle Project
Our
Plan
:
Have Students Design or do
one
of the following things
1.
A
n Early Detection system (to
detect beetles early)
(or)
2.
An
experiment that validates current methods of
detection
3.
Present opposing opinions on beetle kill
(Research Lead Discussion)
Early Detection
System
Introduce students to
Beetle life cycle
Properties of the blue fungus
Current methods of detection and prevention
Article about Global warming
(Pine Bark Beetles Affecting More than Forests: air
quality and weather)
–
NSF
-
Create a hypothesis
Design an experiment
Discuss results of experiment
Present to the class
Biology: Beetle Project
Project idea
Test Current
Methods
Help student Design experiments that
would test current method
Few current methods
Pheromone packets
Spraying techniques up to four inches
Electronic Kit noise
Slash and burn methods
Biology: Beetle Project
Project idea
http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg
Example
Student Idea
Ideas that student could come up with
on their own
Hypothesis:
Placing pheromone packet on tree will send
beetles to trees next to it.
Infected wood would be more acidic than non
-
infected wood.
Beetles favor
lodgepole
due to the resistance
other trees have to pine beetles
Biology: Beetle Project
Project idea
http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg
Example
Student Idea
Ideas that student could come up with
on their own
Material and Methods
Observe current trees with patches and without
patches (quantify)
Build a wood crushing and dissolving kit. Use a
pH indicator to see if one sample is more
acidic than the other
Identify different species of trees and graph
vs
presence of infection
Biology: Beetle Project
Project idea
http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg
Student comparison
of cause
Human impact vs. natural cycle
Students conduct research
Students present research
Student discuss research with peers
Biology: Beetle Project
Project idea
Beginning
of week
Discussions and small readings
Discuss the concept a niche
Read about extinction and the
interdependence of species on one
another
Introduction to Experimental Design
Introduction to Project Design
Biology: Beetle Project
1 Week Plan
Middle
of week
Students Draw Up Proposal
Give students time and help to develop a
beginning to end research proposal
Break it up or all together
Build and test their apparatus
Biology: Beetle Project
1 Week Plan
End
of week
Students Present to the class their
findings
Help student develop presentation
Let student present to the class
Biology: Beetle Project
1 Week Plan
Biology: Introduce Lab Quest
What is
LabQuest
?
Objective:
Introduce the connection between math, technology, and biology in a 9
th
grade
Biology classroom.
Our Plan:
Develop micro lessons that introduce and integrate these concepts
Use micro lesson in classroom
Biology: More Ideas
Design Bug catchers (pitfall traps) for current
Ecology lab
Learn how to design and work with limited materials
Model animal movement/migration (Monarch
Watch)
Add GPS sensor to prairie ecology project and
relate to size/scale of student drawn maps
AP Biology: Slovenia, Phages and
Bioinformatics
Objectives:
Expose students to international connections
Introduce and use
Bioinformatic
software
Our Plan
Design a parallel experiment with the students from
Slovenia that involves isolating soil
bacteriophages
AP Biology: Visualization Software and
Molecular Interactions
Objective: Introduce concepts of bioinformatics while
teaching molecular interactions
Our Plan: Design lesson and lab that incorporate the use
of bioinformatics software
GLI1 Promotes CDK4
Activation?
AP Biology: Regulation of Cell Cycle
Objectives:
Connect concepts learned in class to research currently
being conducted
To create lessons that make the complex cellular
interaction inspiring and memorable for the students
Our Plan
Have the fellow or a guest give a simplified research
proposal presentation
Design a game or activity that relates to cell cycle
regulation
GLI1 Promotes CDK4
Activation?
Science Olympiad Team
Rocky Mountain has a Science Olympiad team which
must complete several building events for competition
(robotics, bottle rockets, egg carrying devices,
bridges/towers)
Summary
Anatomy and Physiology
Lessons
New/Enhanced
LabQuest
labs
Bioinformatics/Tissue Unit
Kinesthetic Activity/NMJ
Biology
Beetle Project (early
detection)
Introduce
LabQuest
AP Biology (next semester)
Collaboration with Slovenia
(Phages and Bioinformatics)
Micro lessons that
incorporate visualization
software of molecular
interactions
Regulation of cell cycle
Game/activity
Short presentation of
current research involving
regulation factors
Questions?
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