GK-12 at Rocky Mountain High School 2011

signtruculentBiotechnology

Oct 2, 2013 (3 years and 8 months ago)

96 views

Carol
Seemueller

and Katherine Kiwimagi

Ideas for GK
-
12 and Rocky
Mountain High School

Big Picture Outline


Anatomy and
Physiology


Lessons


New/Enhanced

LabQuest

labs


Bioinformatics/Tissue unit


Kinesthetic Activity/NMJ


Biology


Beetle Project (early
detection)


Introduce
LabQuest



AP Biology (next semester)


Collaboration with Slovenia
(Phages and Bioinformatics)


Micro lessons that
incorporate visualization
software of molecular
interactions


Regulation of cell cycle


Game/activity


Short presentation of
current research involving
regulation factors


Anatomy and Physiology: Lab Quest Micro
Lessons

http://upload.wikimedia.org/wikipedia/commons/4/46/DNA_Repair.jpg



Objective:


Emphasizing the connection between math, technology
and human physiology


Our Plan:


Develop micro lessons that integrate these concepts

1)
Grip strength lab (student write a hypothesis for muscle
fatigue
---

go to literature we provide to see what scientists
today think)

2)
Skin temperature lab (micro lesson that connects rate to slope
using students collected data)

Anatomy and Physiology: Introduce
Bioinformatics



Objective: Introduce bioinformatics while
studying tissues



Our Plan:


Find a Clinical Study related to a tissue defect caused by
genetics


Develop a lesson that has students use bioinformatics
software such as BLAST to help solve or better understand
the Clinical Case

Anatomy and Physiology: Model a
Neural Muscular Junction


Objective:


Students will increase their understanding of the
neuromuscular junction through a kinesthetic activity.



Our Plan:


Introduce the Neuromuscular Junction


Students will build a model of the neuromuscular
junction that reflects the relationship between form,
function, and cell communication


Anatomy and Physiology: Develop a
VO
2
max lab using lab quest


Objective:


To develop a new VO
2

max lab for the
LabQuest technology



To have students apply their knowledge of math to
the data they collect


Our Plan:


Find a contact in the Exercise and Sports Science
Department at CSU that would give a tour to
students and talk about VO
2

max


Develop lab that has student calculate their own
VO
2

max




Anatomy and Physiology: Expand on the
students understanding of
Bioinfomatics



Objective: Using bioinformatics software,
connect the dots between DNA and Cell signaling



Our Plan:


Find a Clinical Study related to a cell signaling defect
caused by genetics (Cystic Fibrosis / Asthma…)


Develop a Micro lesson that has students use
bioinformatics software such as BLAST to help solve and
better understand the Clinical Case

Anatomy and Physiology: Other Ideas


Possible collaboration

about testing the
characteristics of Bone


Design an EMG controlled Device


Biology: Beetle Project


Objectives:


“connect the dots”



relating rates of infestation “math to ecology”


To see the interdependence of science


Math, Engineering, Chemistry, Biology


State standards #2 and #9


Introduce the Niche concept


Brief introduction of Evolution


(golden toad article extinction/adaptation)


Application of the scientific method


Experiment design, Data analysis and Presentation



Biology: Beetle Project


Our

Plan
:


Have Students Design or do
one

of the following things

1.
A
n Early Detection system (to

detect beetles early)
(or)

2.
An

experiment that validates current methods of
detection

3.
Present opposing opinions on beetle kill
(Research Lead Discussion)



Early Detection
System


Introduce students to


Beetle life cycle


Properties of the blue fungus


Current methods of detection and prevention


Article about Global warming


(Pine Bark Beetles Affecting More than Forests: air
quality and weather)

NSF
-


Create a hypothesis


Design an experiment


Discuss results of experiment


Present to the class

Biology: Beetle Project

Project idea

Test Current
Methods


Help student Design experiments that
would test current method


Few current methods


Pheromone packets


Spraying techniques up to four inches


Electronic Kit noise


Slash and burn methods


Biology: Beetle Project

Project idea

http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg

Example
Student Idea


Ideas that student could come up with
on their own


Hypothesis:


Placing pheromone packet on tree will send
beetles to trees next to it.


Infected wood would be more acidic than non
-
infected wood.


Beetles favor
lodgepole

due to the resistance
other trees have to pine beetles

Biology: Beetle Project

Project idea

http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg

Example
Student Idea


Ideas that student could come up with
on their own


Material and Methods


Observe current trees with patches and without
patches (quantify)


Build a wood crushing and dissolving kit. Use a
pH indicator to see if one sample is more
acidic than the other


Identify different species of trees and graph
vs

presence of infection



Biology: Beetle Project

Project idea

http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg

Student comparison
of cause


Human impact vs. natural cycle


Students conduct research


Students present research


Student discuss research with peers

Biology: Beetle Project

Project idea

Beginning

of week


Discussions and small readings


Discuss the concept a niche


Read about extinction and the
interdependence of species on one
another


Introduction to Experimental Design


Introduction to Project Design

Biology: Beetle Project

1 Week Plan

Middle

of week


Students Draw Up Proposal


Give students time and help to develop a
beginning to end research proposal


Break it up or all together



Build and test their apparatus

Biology: Beetle Project

1 Week Plan

End

of week


Students Present to the class their
findings


Help student develop presentation


Let student present to the class

Biology: Beetle Project

1 Week Plan

Biology: Introduce Lab Quest


What is
LabQuest
?




Objective:


Introduce the connection between math, technology, and biology in a 9
th

grade
Biology classroom.




Our Plan:


Develop micro lessons that introduce and integrate these concepts


Use micro lesson in classroom




Biology: More Ideas


Design Bug catchers (pitfall traps) for current
Ecology lab


Learn how to design and work with limited materials


Model animal movement/migration (Monarch
Watch)


Add GPS sensor to prairie ecology project and
relate to size/scale of student drawn maps


AP Biology: Slovenia, Phages and
Bioinformatics


Objectives:


Expose students to international connections


Introduce and use
Bioinformatic

software



Our Plan


Design a parallel experiment with the students from
Slovenia that involves isolating soil
bacteriophages

AP Biology: Visualization Software and
Molecular Interactions

Objective: Introduce concepts of bioinformatics while
teaching molecular interactions


Our Plan: Design lesson and lab that incorporate the use
of bioinformatics software

GLI1 Promotes CDK4
Activation?

AP Biology: Regulation of Cell Cycle


Objectives:


Connect concepts learned in class to research currently
being conducted


To create lessons that make the complex cellular
interaction inspiring and memorable for the students


Our Plan


Have the fellow or a guest give a simplified research
proposal presentation


Design a game or activity that relates to cell cycle
regulation


GLI1 Promotes CDK4
Activation?

Science Olympiad Team





Rocky Mountain has a Science Olympiad team which
must complete several building events for competition
(robotics, bottle rockets, egg carrying devices,
bridges/towers)

Summary


Anatomy and Physiology


Lessons


New/Enhanced
LabQuest

labs


Bioinformatics/Tissue Unit


Kinesthetic Activity/NMJ


Biology


Beetle Project (early
detection)


Introduce
LabQuest



AP Biology (next semester)


Collaboration with Slovenia
(Phages and Bioinformatics)


Micro lessons that
incorporate visualization
software of molecular
interactions


Regulation of cell cycle


Game/activity


Short presentation of
current research involving
regulation factors


Questions?