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Oct 23, 2013 (4 years and 17 days ago)

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HUMAN HEREDITY

Biology 3350
-
001
,
Spring
-
20
1
3


Dr. Purnima Basu Neogi


Tentative Syllabus



Goals for Human heredity
: The overall goals for this course are for you to develop an
understanding for different aspects of genetics and molecular biology, which
will help
you to learn the subject Human heredity.


Instructor: Dr. Purnima Basu Neogi

Office
-

Bilogy:

A246A

Telephone:

940
-
565
-
4213

E
-
mail:

purnima@unt.edu


Office hours:

Monday
,
Wednesday
-
10:00am
-
11
:00
a
m

or by app
ointment.


Text Book:

HUMAN HEREDITY: PRINCIPLES AND ISSUES, by MICHAEL R.
CUMMINGS,

Brooks/Cole Cengage Learning,
Eighth
E
dition.


OPTIONAL TEXT:

CONCEPTS OF GENETICS
,
by

WILLIAM S. KLUG AND
MICHAEL R. CUMMINGS, Prentice Hall,
Eighth

Edition
.


Class
time and place:

Monday, Wednesday, Friday, 9.00
-
9.50 am,
Room
PHYS 112
.


Prerequisites:

Successful completion of Biol. 1110 and 1115 is required.


Assessment:

Your final grade will be determined as follows:


A 90% or higher


B 80
-
89.99%


C
70
-
79.99%


D 60
-
69.99%


F below 60%


Tentative lecture and exam schedule:

This is a tentative lecture and exam schedule,
subject to change. If and when there are changes announcements will be made in the
class.


Class #

Dates

Topic

Reading


1 (
Mon
.)

Jan 14
, 20
1
3

A Perspective on Human
Genetics

Chap. 1


2 (
Wed
.
)

Jan

16
, 20
1
3


Cell
s

and
Cell Division

Chap. 2


3 (
Fri
.
)

Jan
18
, 20
1
3

Cell
s

and
Cell Division


Chap. 2


4 (
Mon
.
)

Jan 21
, 20
1
3


No class



5 (
Wed
.)

Jan 23
, 20
1
3

Cells Division,
Mitosis,
Meiosis



Chap. 2


6. (
Fri
.)

Jan 25
, 20
1
3

Transmission of Genes
from Generation to
Generation

Chap. 3


7. (
Mon
.)

Jan 28
, 20
1
3

Transmission of Genes
from Generation to
Generation

Chap. 3


8. (
Wed
.)

Jan 30
, 201
3

Transmission of Genes
from Generation to
Generation

Chap 3


9. (
Fri
.)

Feb 1
, 201
3

Review


Chap.
1, 2, 3


10. (
Mon
.)

Feb
4
, 201
3

TEST
#

1

Chap 1,2,3


11. (
Wed
.)

Feb
6
, 201
3

Pedigree Analyses in
Human Genetics

Chap. 4



12. (
Fri
.)

Feb 8
, 201
3

Pedigree Analyses in
Human Genetics

Chap 4



13. (
Mon
.)

Feb 11
, 201
3

Cytogenetics:Karyotypes
and Chromosome
Aberrations

Chap 6


14. (
Wed
.)

Feb 13
, 201
3

Cytogenetics:Karyotypes
and Chromosome
Aberrations

Chap 6


15. (
Fri
.)

Feb 15
, 201
3

Cytogenetics:Karyotypes
and Chromosome
Aberrations

Chap. 6


16. (
Mon
.)

Feb
18
, 201
3

Cytogenetics:Karyotypes
and Chromosome
Aberrations

(Presentation
-

slide show)

Chap. 6



17.
(
Wed
.)

Feb 20
, 201
3

Cytogenetics:Karyotypes
and Chromosome
Aberrations

(Presentation
-

slide show)

Chap. 6


18. (
Fri
.)

Feb 22
, 201
3

Development
and Sex
Determination

Chap 7


19.
(
Mon
.
)

Feb. 25
, 201
3

DNA structure and
chromosomal
organization

Chap
8

21. (
Wed
.
)

Feb.

2
7
, 201
3

DNA structure and
chromosomal
organization

Chap 8


22. (
Fri
.
)

Mar. 1
, 201
3

DNA structure and
chromosomal
organization

/
Review

Chap 4,

6,

7,

8


23. (
Mon
.
)

Mar.
4, 2013


TEST # 2

Chap
4,

6,

7,

8


24. (
Wed
.)

Mar.
6
, 201
3

Teratology and Human
development


Guest Lecture


25. (
Fri
.)

Mar.
8
, 201
3

Teratology and Human
development


Guest Lecture


26. (
Mon
.)

Mar. 11
-
17
, 201
3

Spring break



27. (
Mon.
)

Mar. 18
, 201
3

Genetic Screening and
Prenatal Diagnosis

Guest Lecture


28. (
Wed
.)

Mar.
20
, 201
3

Genetic Screening and
Prenatal Diagnosis


G u e s t L e c t u r e


2 9. (
F r i
.
)

M a r. 2 2
, 2 0 1
3

G e n e E x p r e s s i o n: f r o m
G e n e s t o P r o t e i n s


C h a p.
9


3 0. (
M o n
.
)

M a r.
2 5
, 2 0 1 3


G e n e E x p r e s s i o n: f r o m
G e n e s t o P r o t e i n s


C h a p.

9


3 1. (
We d
.)

M a r. 2 7
, 2 0
1
3


G e n e E x p r e s s i o n: f r o m
G e n e s t o P r o t e i n s


C h a p
.

9


3 2. (
F r i
.)

M a r. 2 9, 2 0 1 3


M u t a t i o n: T h e s o u r c e o f
G e n e t i c V a r i a t i o n

G e n e
a n d C a n c e r


C h a p
.

1
1


3 3.(
M o n
.
)

A p r i l 1, 2 0 1 3


M u t a t i o n: T h e s o u r c e o f
G e n e t i c V a r i a t i o n


C h a p
.

1
1


3 4 (
We d
.
)

A p r i l 3, 2 0 1 3


R e v i e w

C h a p.
9, 1 1,
1 2,



3 5 (
F r i
.
)

A p r i l
5, 2 0 1 3


T E S T # 3


C h a p.
9,

1 1
,

1 2,

GL


36 (
Mon
.
)

April 8, 2013


Mutation: The source of
Genetic Variation


C h a p.1
2


3 7 (
We d
.
)

A p r i l 1 0, 2 0 1 3


G e n e a n d C a n c e r

C h a p.1 2


3 8 (
F r i
.
)

A p r i l 1 2, 2 0 1 3


G e n e a n d C a n c e r

C h a p.1 2


3 9 (
M o n
.
)

A p r i l 1 5, 2 0 1 3


A n i n t r o d u c t i o n t o
c l o n i n g a n d r e c o mb i n a n t
D N A


C h a p.1 3


4 0 (
We d.
)

A p r i l 1 7, 2 0 1 3


A n i n t r o d u c t i o n t o
c l o n i n g a n d r e c o mb i n a n t
C h a p.1 3


DNA

41 (
Fri
)

April 19, 2013


Genes and Immune
System

Chap.
1
7


42 (
Mon
)

April 22, 2013


Genes and Immune
System

Chap. 1
7


43 (Wed.)

April 24, 2013


Biotechnology and
society.


Chap. 1
4


44 (Fri.)

April 26, 2013


Human Genome Project



Chap. 15


45 (Mon.)

April 29, 2013


Genomics


Chap. 15


46.(Wed.)

May 1, 2013

REVIEW




May 3, 2013

Reading day



47. (Wed.)

May 8, 2013

Final Exam

Chap.
Guest
lectures,

1
3,14,15,
17

PHYS 112


Testing and
grading:

Four exams, including the final examination, will be given.
All
Exam
s

will be non
-
comprehensive. The breakdown for grading is as follows:


50

+
50

+
50

+
50

=
2
00


Exam I + Exam II + Exam III + Exam IV


*
Policy regarding grading:

If you think the
test has been mis
-
graded, write a note of
explanation and turn it in to
gether with the graded exam
to the instructor within two
lecture periods. After 2 lecture periods, grades will not be changed.



Make
-
up exam



Only on doctor’s note.

The make up exam will more difficult so it is
not to your advantage to miss an exam. You must notify me in writing of your intention
to take a make up exam.


Academic integrity:

The University (and the professor) expects the highest standards of
academic

integrity. A description of the code of Student Conduct and Discipline is in the
student handbook.


Academic dishonesty will not be tolerated. Any student caught cheating in any form will
be punished to the full extent of University regulations, including

but not limited to
receiving a zero for the exam and an F for the course.


Disabilities:

“The University of North Texas makes reasonable academic
accommodation for students with disabilities. Students seeking accommodation must first
register with the Of
fice of Disability Accommodation (ODA) to verify their eligibility. If a
disability is verified, the ODA will provide you with an accommodation letter to be
delivered to faculty to begin a private discussion regarding your specific needs in a
course. You m
ay request accommodations at any time, however, ODA notices of
accommodation should be provided as early as possible in the semester to avoid any
delay in implementation. Note that students must obtain a new letter of accommodation
for every semester and m
ust meet with each faculty member prior to implementation in
each class. For additional information see the Office of Disability Accommodation
website at
http://www.unt.edu/oda
. You may also contact them by phone at
9
40.565.4323.”



This statement and other ODA information is available on the ODA website
http://www.unt.edu/oda


Important Note:

State common law and federal copyright law protects my lectures. You
are not authorized
to record my lectures, to provide your notes to anyone else or to make
commercial use of them without express prior permission from me.


Homework is assigned, but not graded. Completion of homework will help you prepare
for the exam.


Please remember w
hen you are in lecture you are not to have your cell phone on.