Genetic Engineering Biotechnology & Helath - MsKhan

mutebabiesBiotechnology

Dec 6, 2012 (4 years and 7 months ago)

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Genetic Engineering:

Redesigning Life

8.3

Genetic Engineering

Heirloom Varieties

Biopharming

Biopharming


genetically engineered host organisms
are used to make pharmaceuticals or
other medically
-
important proteins



proteins can be isolated from milk (e.g.,
cows, goats) or seeds (e.g., safflowers)
and used

Transgenic Organisms


Why transgenic (GM) animals and plants?


usually cheaper to maintain than
transgenic bacteria


have the ability to produce larger more
complex proteins

Transgenic Plants


GM canola and other field crops are
usually engineered to resist herbicides,
reducing the farmer’s costs



great potential to provide food in
developing countries, but cost of seeds
can be prohibitive

Knockout Mice


engineered to have
at least one gene
turned off



useful for studying
effects of specific
genes on human
health

Societal Concerns?




interbreeding and/or competition with
native plants or animals


may contain toxins that harm
consumers (e.g., GM safflower)


regulation? patents?

Biotechnology & Health

8.4

Genetic Screening

Ontario Newborn Screening


metabolic disorders


endocrine disorders


blood disorders


cystic fibrosis

Hereditary Disorders


early identification of some
hereditary disorders can help to
allow for treatment to minimize
symptoms through:


controlled diet


providing missing proteins


surgery

Gene Therapy



offers the possibility of correcting the
genetic defect



germ
-
line gene therapy


somatic gene therapy