What is Biotechnology?

mutebabiesBiotechnology

Dec 6, 2012 (4 years and 11 months ago)

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WHAT IS
BIOTECHNOLOGY?

Biotech News

Science Dailey

APPLICATIONS


Medicine


Pharmacogenomics
-
Designer
Drugs


Pharmaceutical products
-
Insulin


Biomedical engineering


Genetic testing


Gene therapy


Cloning


Human Genome Project


Agriculture


Improve yield


Reduce vulnerability to stress,
pest, etc.


Increase nutrition, taste, etc.


Production of novel substances


Biofuels





Biological engineering


Cell and tissue cultures


Bioremediation and
Biodegradation


Ecology and Diversity


Evolution


Biogeography


Biohistory

Yali Friedman, Ph.D.




MYOSTATIN GENE

Land Mine Detection


Without this effort,


that is dangerous to our military,


children are

maimed.

Land Mine Detection


How biotechnology helps



Patented transgene added to plants



When metal from mine is detected



Plant turns from green to red



Technology developed by
Aresa Biodetection

Mine detected

Golden Rice is Modified to be Provide a Dietary Source of Vitamin A

Worldwide,
7
% of children suffer vitamin A deficiency, many of them living in
regions in which rice is a staple of the diet.

Golden rice (yellow)
with standard rice
(white).

The Biotechnology
of Reproductive
Cloning

Even under the best of
circumstances, the
current technology of
cloning is very
inefficient.


Cloning provides the
most direct
demonstration that all
cells of an individual
share a common
genetic blueprint.


The Inner Cell Mass is the Source of Embryonic Stem Cells

The embryo is destroyed by separating it into individual cells for the collection
of ICM cells.

Human Insulin Production by Bacteria

6
) join the plasmid and human fragment

and cut with a restriction enzyme

Human Insulin Production by Bacteria

Mix the recombinant plasmid with
bacteria.

Screening bacterial cells to learn which contain the human insulin gene is the
hard part.

Route to the Production by Bacteria of Human Insulin

A fermentor used to grow
recombinant bacteria.

This is the step when gene cloning takes place.

The single recombinant plasmid replicates within a cell.


Then the single cell with many recombinant plasmids produces trillions of
like cells with recombinant plasmid


and the human insulin gene.

One cell with the
recombinant plasmid

Pharming

These goats contain the human gene for a clot
-
dissolving
protein that is produced in their milk.

Pharming is the production of pharmaceuticals in animals engineered to
contain a foreign, drug
-
producing gene.
.

GM Fish

Restore, Improve, and Extend
Human Life

Sources of Biological Evidence


Blood


Semen


Saliva


Urine


Hair


Teeth


Bone


Tissue


DNA, the Law, and Many Other Applications



The Technology of DNA Fingerprinting

A DNA fingerprint used in a murder case.

What are we looking at? How was it produced?

The defendant stated that the blood on his clothing was his.

13
CODIS Core STR Loci
with Chromosomal Positions

CSF
1
PO

D
5
S
818

D
21
S
11

TH01

TPOX

D
13
S
317

D
7
S
820

D
16
S
539

D
18
S
51

D
8
S
1179

D
3
S
1358

FGA

VWA

AMEL

AMEL