ChE 4552 Introduction to Biotechnology - Che.nthu.edu.tw

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Feb 12, 2013 (4 years and 5 months ago)

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ChE 4552 Introduction to Biotechnology


Instructor:
胡育誠

(Andy Hu)

Office: 307

(
x
3
3642
)

E
mail:
yuchen@che.nthu.edu.tw


ychu@mx.nthu.edu.tw

W
eb:
http://www
2
.che.nthu.edu.tw/biohu/


Classroom: 2
21

TA:
呂宥瑩、陳秋伶、吳曉旋

(
327

329)


C
o
urse contents
:
The topics of this course cover basic cell biology, fundamental
genetic engineering,
cell culture,
bioreactor design, downstream bioprocesses and
applications of biotech
nology.


Text
book
:

1.

Colin Ratledge, Bjorn Kristiansen. (2001) Basic Biotechnology. Cambridge
University Press, Cambridge, UK.


Reference:

1.

Shuler ML and Kargi F. (1992) Bioprocess Engineering: Basic Concepts. Prentice
Hall International, London.

2.

Watson, JD
, Gilman, M, Witkowski, J, Zoller, M. (1992) Recombinant DNA.
2
nd

Ed. W.H. Freeman and Co., New York
.

3.

Karp, G. (2002). Cell and Molecular Biology: Concepts and Experiments. 3
rd

Ed.
John Wiley &Sons. New York.

4.

Barnum, S.R. (2005) Biotechnology: an Introdu
ction. 2
nd

Ed.

Thomson Learning,
New York.

5.

Voet, D., Voet, J., (2004) Biochemistry. 3
rd

Ed. (Vol.1) John Wiley & Sons. New
York.

6.

Glick BR and Pasternak JJ. (
2003
) Molecular Biotechnology: Principles and
Applications of Recombinant DNA.
3rd

ed. ASM Press,

Washington, D.C.

7.

Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. (2002)
Molecular Biology of the Cell, 4th Ed. Garland Science, New York.

8.

Doran, P
M
(1995)
Bioprocess
E
ngineering
P
rinciples
. Academic Press. San
Diego.

9.

Blanch, HW, Cla
rk, DS. (1997) Biochemical Engineering. Marcel Dekker. New
York.

10.

Walsh, G. (2002) Proteins: biochemistry and biotechnology. John Wiley & Sons.
New York.

11.

Nester, EW, Anderson, DG, Roberts Jr. CE, Pearsall, NN, Nester, MT. (2001)
Microbiology, A Human Perspe
ctive. McGraw Hill. New York.


Grading

policy
:



Mid
-
term exam:
3
5
%



Final Exam:
4
5
%



Course Participation:
10
%



Quiz: 10
%

Midterm exam:
11
/
1
0

(
Tue
)

Final
e
xam: 1/
12

(T
hr
)

Syllabus

Basics



Chap1 Public Perception of
B
iotechnology




Chap2 Overview of
B
iological Systems




Chap3 Growth and Metabolism




Chap4 Genetic Engineering
-
P
ro
c
aryote




Chap5 Genetic Engineering
-
Y
east and
F
ungi




Chap6
Culture of Animal Cells



Chap7
Microbial
P
rocess
K
inetics




Chap8
Bioreactor




Chap9 Downstream
P
rocessing



Applicati
ons:



Chap 14

Amino Acids



Chap 1
5

Organic Acids



Chap 1
6

Microbial
P
olyhydroxyalkanoates,
P
olysaccharides and
L
ipids



Chap 1
8

Antibiotics



Chap 20 Recombinant
Pr
oteins