Nature Publishing Group


Oct 23, 2013 (4 years and 8 months ago)


Nature Publishing Group

Quality, Impact & Vision


Presented by

Professor Nick Lemoine, MD PhD

and Publishing Manager, Rebecca Vickerstaff

How to Get Your Paper Published in
Gene Therapy


Nature Publishing Group

Leading scientific publisher

Nature, Nature Research journals,

Nature reviews, NPG academic journals,

Scientific American…

Focus on quality rather than quantity

Serving authors/readers needs


At the forefront of medicine,
Gene Therapy

brings you the latest
research into genetic and cell
based technologies to treat disease. It
also publishes Progress & Prospects reviews and News and
Commentary articles, which highlight the cutting edge of the field.

Key Facts

A founding journal in a field of great potential

First published in 1994

High profile editors

12 issues a year

Print and online publication

Impact Factor 4.538

Online publication within 26 days


To which journal should you send your manuscript?

Questions to ask…

Is your paper within the scope of the journal?

What is the quality of other papers published?

How easy is electronic submission?

How quickly will you receive a decision?

How quickly will your paper be published?

Does the journal offer an ‘open access’ option?

Does the journal reach an appropriate audience?


How much should you worry about Impact Factors?

Impact Factors are important and are currently the predominant
method used to rank journals in terms of quality

Calculated as the number of cites received in the impact factor
year to articles published in the previous 2 years

Gene Therapy
’s 2010 Impact Factor released in June 2011 =

Obviously there are journals with higher IF than
Gene Therapy

Nature Medicine

(25.430) or
Nature Biotechnology


Equally important to think about scope, ease of publication, reach,
promotion and service delivered to you by the Publisher


Journal scope and content

Gene Therapy

covers both the research and clinical applications of the
new genetic therapy techniques currently being developed. Over the last
decade, gene therapy protocols have entered clinical trials in increasing
numbers and as they cover a wide spectrum of diseases, these studies
promise to unite the diverse organ
based specialities into which modern
medicine has become divided.
Gene Therapy

covers all aspects of gene
therapy as applied to human disease, including:

novel technological developments for gene transfer, control and silencing

basic science studies of mechanisms of gene transfer and control of

preclinical animal model systems and validation studies

clinical trial reports which have significant impact for the field

based vaccine development and applications

based therapies including all aspects of stem cells and genetically
modified cellular approaches



Review articles in
Gene Therapy

aim to provide accessible,
authoritative overviews of a field or topic.

Reviews should communicate a sense of enthusiasm, weaving
background information with the latest advances, and placing
both of these elements in the context of the rest of the field.

The abstract describes what the article is about in a succinct,
easily digestible way. It should not contain specialist details,
abbreviations, references or figure citations.

References should concentrate on significant original research


Novel or original findings



Clarity of data and conclusions

Interesting to the international community

Good standard of English (seek help if necessary)

Compliance with ethical standards and approval by
Institutional Review Board if appropriate

Disclosure of possible conflicts of interests by all authors

References complete and up

What are Editors looking for?


Preparing for submission

Read the Instructions to Authors

Regular manuscripts submitted to the journal follow a
standard format

When ready to submit, ensure that you have available:


All authors’ names, postal and e
mail addresses


The complete manuscript with all images, tables and

figures in the appropriate format


Cover letter drawing the editor’s attention to any special


At this point you can also choose to ask NPG to deposit the
author’s accepted version into PubMed Central on behalf of all
authors upon publication or have your paper published open


Open Access

Gene Therapy

now offers authors open access

option to pay a one
off fee

To have your final published version made freely available immediately on

publication rather rely on readers who have paid subscriptions

Fee is £2,500

NPG already complies with major funding agencies but this is a further
step forward

Final version automatically deposited into PubMed Central

Choose one of two creative commons licences

Research receives greater visibility

11 papers published open access in 2011 so far

expected growth year on



The peer review process

Upon submission your manuscript will be quality
checked by the Journal Manuscript

Coordinator and then assigned to the Editors who:

Determine if the manuscript is within the scope of the Journal

Assess whether the paper is of sufficient novelty and quality to be sent out for

If NO a rapid reject decision will be made to enable the author to submit
to another journal as quickly as possible

If YES the Editor will ask 2 or more experts to review the manuscript as
rapidly as they can

Based on the reviewers’ reports the Editor will make an initial decision to
accept, to reject or to ask for revision.

The decision letter is sent to the corresponding author


Revision of manuscript

If you are asked to revise your manuscript a revision you will have to
submit a revised version within 3 months.

You must include a covering letter indicating exactly how you have
responded to each point raised by the Editor and reviewers.

If you judge the reviewer to be incompetent or not to have understood
your paper, you can explain this clearly in your reply and but preferably
using tactful language!

Upon resubmission your paper may be sent for review again and you
may be asked to carry out further revision.

Acceptance is never guaranteed until you receive the editor’s letter telling
you the paper has been accepted for publication.

If accepted, your paper will be passed on to the NPG production


The production process

A production editor will ensure your paper meets
Gene Therapy
’s house

Check punctuation, grammar, and consistency of terminology

Check pharmaceutical names and abbreviations

Check references

Figures and tables are formatted and the manuscript is typeset

Reasons for delays to starting work on a paper:

Artwork in wrong format

Licence To Publish form not complete

Open access payment form not received

Page proofs are e
mailed to the corresponding author within 8 weeks of

corrections to be made to a .pdf version.

Once paper is returned a Document Object Identifier (DOI) number is
assigned and paper is ‘queued’ for advanced online publication (AOP).


Advanced online publication (AOP)

Papers are published online in batches once a week

Your paper should appear online within 26 days of receipt in
production providing you return your proofs in a timely manner.

This is the final published version and can now be cited.

Your paper is recorded in PubMed as soon as it is published
online, ensuring more people see your article over a longer
amount of time.

If you have chosen the open access option your paper will be
freely available for all to view; if not, for one year the full text
version will be available to persons who have paid subscriptions.

Ideally the print version of your paper will appear within 4 months
of acceptance


Once published: promotion and visibility

Large subscriber base and high web traffic.

Electronic table of contents (e
ToC alerts) with direct links to all newly
published articles are sent to over 100,000 registered users each month.

All articles are included in key abstracting, indexing and linking services
including ISI, PubMed, Medline, Embase and Crossref.

Selected articles are press

Selected articles appear on the Nature homepage (, in
web focuses, and on subject area pages, all of which highlight the latest
and best research from across the NPG portfolio.

Articles are included in a range of promotional campaigns

print adverts
/ reprint collections / conference promotion / online promotions / email


Please submit your article online to
Gene Therapy

Any Comments or questions?