biomanufacturing - NCABR

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Dec 5, 2012 (4 years and 11 months ago)

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Biomanufacturing

in North Carolina


Biomanufacturing in N.C.


What is
biotechnology
?


A collection of technologies that use
living

cells

and/or
biological
molecules

to solve problems and make
useful products.

Biomanufacturing in N.C.


The making of these products is
called
biomanufacturing
or
bioprocessing.


Biomanufacturing in N.C.

A Growing Industry in N.C.



16 biomanufacturing companies



More than 30 other companies engaged in
related manufacturing of pharmaceuticals,
diagnostics and medical devices



Together, they employ more than 20,000
people.



Biomanufacturing in N.C.

Types of products made in N.C. include:



Vaccines for humans and animals


Biopharmaceuticals


Amino acids


Industrial enzymes


Therapeutics isolated from blood


Custom DNA sequences

Biogen Idec


Produces biopharmaceuticals to treat cancer,
multiple sclerosis and inflammatory diseases.

Its large
-
scale manufacturing in

Research Triangle Park

is one of the largest

cell culture facilities

in the world
.



Ajinomoto

Is a world leader in the
production of amino acids,
the building blocks of
proteins. Like many
bioprocessing facilities, the
Raleigh plant operates


at full capacity

24 hours a day,

365 days a year.



Is
a world leader in production of
recombinant protein
biopharmaceuticals. Its state
-
of
-
the
-
art
facilities are located in Research
Triangle Park.

Diosynth RTP

AlphaVax


Is developing a new
vaccine technology with
broad applications
against infectious
disease, cancer and
biodefense threats. Its
manufacturing plant is
located in Lenoir.


Novozymes North America

Is located on 1,600 acres
in Franklinton. It is the
largest multi
-
purpose
enzyme manufacturing
plant in the United States

and employs

approximately

350 people.


Novozymes is the biotech
-
based world leader in
industrial enzymes and microorganisms.

Embrex

Is an international ag
biotech company that
developed the first
in ovo

(in the egg) injection
system. It eliminates the
need for manual
vaccination of newly
hatched broiler chicks.
The manufacturing plant
is located in

Laurinburg
.

Wyeth Vaccines


Operates one of the
world’s largest
vaccine facilities in
Sanford. The
vaccines that
eliminated small
pox and polio in the
U.S. came from
Wyeth laboratories.


Greer Labs

Is a leading supplier
of allergy testing
and treatment
materials. Its
manufacturing
facility is located in

Lenoir.

KBI BioPharma

Is a contract
biomanufacturer
in Durham. The
company
produces a
variety of bio
-
pharmaceuticals
for other
companies.

MWG Biotech

Offers products and
services for gene
research.

The company
produces custom
DNA sequences.
The facility is
located in
High Point.

Argos Therapeutics


Is developing
therapeutic
vaccines in
Durham, which are
given to treat
(instead of
prevent) diseases
such as cancer
and HIV/AIDS.

Biolex


Produces hard
-
to
-
make therapeutic
proteins by growing
them in the aquatic
plant Lemna
(duckweed).

The biomanufacturing
plant is in Pittsboro.

Isolates a variety of therapeutic proteins
from human blood and plasma in its
Clayton, N.C., facility.

The diseases these proteins treat
include:



Hemophilia



Clotting disorders



Shock


Burns




Immune disorders



Hepatitis


Tetanus



Rabies exposure.


Talecris Biotherapeutics

Archer Daniels Midland


Is one of the
largest
agricultural
processors in the
world. The plant,
in Southport,
N.C., produces
citric acid.

Corn Products International


Produces
high
-
fructose
corn syrup
and starch
in Winston
-
Salem
.

Merck & Co.

Broke ground on a new
biomanufacturing
facility in 2004. When
completed in 2008,
the Durham facility
will produce vaccines
for chicken pox and
measles
-
mumps
-
rubella (MMR).