Bases SOP - University of Kansas Medical Center

grapeafterthoughtSoftware and s/w Development

Dec 14, 2013 (3 years and 7 months ago)

108 views

Environment, Health and Safety Safe Operating Procedure:

Base


University of Kansas Medical Center

Safe

Operating Procedure


BASE

Purpose/Scope
:

The purpose of this safe operating procedure is to guide lab
oratory staff in the safe handli
ng
,
storage

and
use of

basic

chemicals. It provides general safety recommendations to reduce the risk
of exposure and accidents.

This procedure applies to all laboratories that use

basic

chemicals
.

(Please contact Environment Health and Safety for any
questions or co
ncerns, 8
-
1081 or
ehs@kumc.edu

)

Definition:

A corrosive

material

means a liquid or solid that causes full thickness destruction of human skin
at the site of contact within a specified period of time; or, a liquid that has a severe corrosion rate
on steel or aluminum based on the criteria in the code of federal regulati
ons sec. 173.137 ( c )(2).
Under corrosive material
,

they are categorized by either b
eing basic or acidic;


Base
-

any corrosive
material that has a pH 10 or above.

Examples

Bases
-

Caustic Soda, Sodium Hydroxide, Potassium Hydroxide, etc.

Hazards

Very ha
zar
dous in case of skin contact, eye contact, and

ingestion. Slightly hazardous in case

of
inhalation.

Liquid or spray mist may produce tissue damage particularly on mucous membranes
of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalation of the spray
mist may produce severe irritation of respiratory tract, characterized by coughin
g, choking, or
shortness of breath. Severe over
-
exposure can result in death. Inflammation of the eye is
Environment, Health and Safety Safe Operating Procedure:

Base


characterized by redness, watering, and itching. Skin inflammation is characterized by itching,
scaling, reddening, or, occasionally, blistering.

Route
s of Exposure

If any symptoms should occur, seek medical advice.

Eye contact
: Immediately flush with water for 15 minutes.
Seek medical attention immediately.

Skin contact
: Wash with soap and water.
Seek medical attention if necessary.

Inhalation
: Report to fresh air, keep calm and at rest.
Seek medical attention.

Ingestion
: Rinse mouth thoroughly. DO NOT induce vomiting and seek medical attention.

Handling/Storage
:

Handling

Bases
-

Keep container

(s) dry and do

not breathe dust. Never add water t
o this product. In case of
insufficient ventilation, wear suitable respiratory equipment. If you feel unwell, seek medical
attention and show the label when possible. Avoid contact with skin and eyes. Keep away from
incompatibles such as oxidizing agents,
reducing agents, metals, acids, alkalis, moisture.

Storage

Bases
-

Keep containe
r (s) tightly closed and

in a cool, well
-
ventilated
area.


Spills and Accidents
:

Bases
-

Stop leak if without risk. Do not get water inside container

(s)
. Do not touch spilled
material. Use water spray to reduce vapors. Prevent entry into sewers, basements or confined
areas; dike if needed. Neutralize the residue with a dilute solution of acetic acid. Be careful that
the product is not present at a concentration level above TLV.

Check TLV on the MSDS and
with local authorities
.
Ensure eye wash and safety shower locations are known.

Fill out incident report form:
h
ttp://www.kumc.edu/compliance/environment
-
health
-
and
-
safety
-
office
-
/forms/incident
-
report
-
form.html


(Please contact Environment Health and Safety
for any questions or concerns, 8
-
1081 or
ehs@kumc.edu

)

Environment, Health and Safety Safe Operating Procedure:

Base


PPE

(personal protective equipment)

and Engineering/Ventilation Controls
:

Engineering/ventilation controls and/or proper work practices should be used to
eliminate
hazards. If these alone do not eliminate the hazards present then
PPE
should be used
.

PPE is
in
effective if it is
not used properly.

PPE

Personal protection
:
Avoid

contact with skin and eyes when handling the product. Use only in
well ventilated areas.

Inhalation
: In case of insufficient ventilation, wear suitable respiratory equipment.

Hands and
Skin
: wear suita
ble protective gloves (nitrile), lab coat, etc.


Eyes
: Wear safety
glasses/
goggles.

Engineering/Ventilation Controls

Use only in well ventilated areas.

Work conducted under a certified chemical fume hood is recommended. Please see the
fo
llowing link for information regarding work with chemical fume hoods:
http://www.kumc.edu/Documents/compliance/safety/2012%20Chemical%20Fume%20Hood%20P
lan.pdf


Waste Disposal
:

The EHS office is required by Federal Regulations, the EPA, to properly dispose of all hazardous
waste. Once a lab is ready to discard any hazardous materials, please f
ill out chemical pickup
form

located on the EHS website or follow the link below
:

http://www.kumc.edu/compliance/environment
-
health
-
and
-
safety
-
office
-
/forms/chemical
-
pick
-
up
-
form.html

Special Precautions for animals
:

For any projects involving the use of chemicals or drugs on animals, all researchers must review
and comply with the IACU
C Chemical and Drug Hazard Policy. Additionally, the “Section H”
portion within the IACUC protocol form is the designated location for disclosing all hazards
Environment, Health and Safety Safe Operating Procedure:

Base


(including chemical and drug use) for research inv
olving animal models. The policy

can be
found at
:
http://www.kumc.edu/compliance/office
-
of
-
animal
-
welfare/policies
-
procedures
-
and
-
guidelines/iacuc
-
policies.html
.


Resources:

Consult the individual chemical’s MSDS (or SDS) for additional information about the hazards
and proper handling of each specific chemical. If you do not have an MSDS, several can be
found on the following websites:

http://www.sigmaaldrich.com/united
-
states.html

http://www.fishersci.com/ecomm/servlet/msdssearchhome?showMSDSSearch=Y&storeId=10652

Other Resources:

http://www.kumc.edu/compliance/environment
-
health
-
and
-
safety
-
office
-
.html


Keegan, Robert. J. (2011/2012).

Hazardous Materials, Substances & Wastes C
ompliance Guide.

Kutztown, PA: Robert J. Keegan.