Dr. Monica Rinaldi - Research Publisher

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Oct 23, 2013 (3 years and 5 months ago)

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Editor Profile

Monica Rinaldi

Institute of Translational Pharmacology

Department of BioMedicine


National Research Council
, Italy


Contact

Institute of Translational Pharmacology

(IFT)

National Research Council

(CNR)

Via Fosso del Cavaliere 100


00133 Rome, Italy

Phone: (
+39
)
0649934219

Fax: (+39) 0649934257

E
-
mail:
monica.rinaldi@ift.cnr.it


Commitments and
Accolades




Editor (Invited

Handling Editor)
for the volume “DNA Vaccines”, in 'Methods in
Molecular Biology' series
published by Humana Press, Springer publishing group (
2012
-
present)



Member,
Board of Editors,
Novus International Journal of Biotechnology & Bioscience
, (
Novus Scientia
Journals
,

(
2012
-
present)



Associate Editor,
Journal of
Alzheimer Disease
, (IOS Press publication) (2011)



Member, Institute Committee, Institute of Translational Pharmacology, CNR, (2010
-
present)



Appointed by the Director, Institute of Translational Pharmacology, CNR, in the Commission of reviewers
for the sele
ction of Technicians, Young Investigators, Senior Investigators, Researchers (2010
-
present)



Appointed by the Board of Directors, CNR, in the list of internal expert for the

composition of committees
in the national process of recruiting staff researcher

and technologist

(
2009
-
present
)



Member, Institute Committee, Institute of Neurobiology and Molecular Medicine, CNR,
(
2009
-
2010)



Appointed b
y the Director,
Institute of Neurobiology and Molecular Medicine, CNR, in the Commission of
reviewers for the
selection of Young Investigators, Senior Investigators, Researchers (2003
-
2009)


Current Research



In vivo
n
aked gene transfer

into muscle



Development of specific multigenic plasmid vectors



Pre
-
clinical protocols by systemic delivery of recombinant proteins in animal models of human
diseases.



Anti tumor DNA vaccines in indolent B cell Lymphoma and colon cancer



Pre
-
clinical protocols of genetic immunization against tumor antigens



Combined
therapeutic protocols (vaccination+immunotherapy+chemotherapy)



Development of innovative vaccine formulations for anticancer therapy and/or prevention, intended for
clinical application

Biography

Monica Rinaldi
was born in 19
64

in
Rome
,
Italy
. After graduating
with full honours
in Biology
at

the University
of
Rome
"La Sapienza",
s
he obtained a Ph.D.
in Biotechnology.
From 1995 to 2000 she was a Post
-
Doctoral
Fellow
in Molecular Medicine at the Institute of Neurobiology and Molecular Medicine,
National Research
Council (CNR),
ITALY
.
She was
appointed as

Assistant Professor of General Pathology
at University
Campus Bio
-
Medico of Rome, School of Medicine
(1996
-
2001)
,

and Professor of Molecular Biology
at
Universi
ty Campus Bio
-
Medico of Rome,
School of Engineering
,
Degree in Biomedical Engineering
(
1999
-
2000
).

Since
2001

she is
Research Scientist
at the
Department of BioMedicine, CNR
.
She is
Head

of
Laboratory

of
Medical Biotechnology

at the
Institute of Translational Pharmacology (IFT),

CNR
.
D
r.
Rinaldi

is
the author of more th
a
n
5
0 peer reviewed
scientific
publication
s, including original research articles,
book
chapters

and
invited reviews. She is co
-
inventor of U.S. patents (USPTO) and Principal Investigator of
several grants related to biotechnology applications in medicine. She is
peer reviewer for several scientific
journals.
Her
ma
jor

field

areas
are

Molecular Pathology, Experimental Oncology,


Immunotherapy
and
research interests
focus on
the pre
-
clinical development of innovative
drug formulations

and protocols for
advanced therapies

(
gene therapy and DNA vaccination
)
.

Selected
Recent
Publications

Epitope
-
driven DNA vaccine design employing immunoinformatics against B
-
cell lymphoma: a biotech's
challenge

Iurescia S, Fioretti D, Fazio VM, Rinaldi M

B
iotechnology
A
dvances;


vol
ume

30; p
ages

372
-
383
; Published:
2012


Design and pre
-
clinical development of epitope
-
based DNA vaccines against B
-
cell lymphoma

Iurescia S,
Fioretti D
, Fazio VM,
Rinaldi M
.

Current Gene Therapy
;
volume 11, issue 5; pages 414
-
22;
Published:
2011


Genetic immunization with CDR3
-
based fusion vaccine confers protection and long
-
term tumor
-
free survival
in a mouse model of lymphoma.

Iurescia S,
Fioretti D
, Pierimarchi

P, Signori E, Zonfrillo M, Tonon G, Fazio VM,
Rinaldi M
.

Journal of Biomedicine and Biotechnology
; volume
2010
; Published:
2010


Anti
-
tumor immunity induced by CDR3
-
based DNA vaccination in a
murine B
-
cell lymphoma model

Rinaldi M
,
Fioretti D
, Iurescia S, Signori E, Pierimarchi P, Seripa D, Tonon G, Fazio VM.

Biochemical and Biophysical Research Communications
; volume
370
; pages
279
-
84
;
Published: 2008