8:30-9:05 AM PARKER B. FRANCIS LECTURESHIP

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Nov 16, 2013 (3 years and 10 months ago)

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THOMAS L. PETTY


ASPEN LUNG CONFERENCE

56
th

Annual Meeting


"
The Lung Microbiome: A New Frontier in Pulmonary Medicine



June 5
-
8, 2013

Tuesday, June 4, 2013

--

Evening


5:00
-
7:00 PM

Evening Registration
--

Wine and Cheese Reception

Gant Conference Center


Wednesday, June 5, 2013
--

Mornin
g


8:
00
-
8:15

AM

Introduction/Welcome

Richard J. Martin
, M.D.,

Chair



Sonia C. Flores
,
Ph.D.,
Co
-
Chair

Monica Kraft, M.D., Co
-
Chair


8:15
-
8:30

AM


ABCs of the Lung Microbiome


James
M.
Beck, M.D.

Veterans Affairs Eastern Colorado Health Care System

University of Colorado School of Medicine


M
oderator: XXXXXXX


8:30
-
9:05 AM

PARKER B. FRANCIS LECTURESHIP

"
THE MICROBIOME: WHAT IT MEANS TO HUMAN HEALTH

GOOD OR BAD


Fernando D. Martinez, M.D.

Swift
-
McNear Professor of Pediatrics

Director of the Arizona Respiratory Center

The University of Arizona

Pediatric Pulmonary Center

Tucson, Arizona


9:05
-
9:3
0 AM

Discussion


9:30
-
9:4
5 A
M


ENRICHMENT OF LUNG MICROBIOME WITH SUPRAGLOTIC MICROBES IS
ASSOCIATED WITH INCREASED PULMONARY INFLAMMATION.
Leopoldo N. Segal
1
*
,

A.
Alekseyenko
1
, C.J.

Clemente
2
, C.

Aliferis
1
, K.

Berger
1
, R.

Goldring
1
, W.
N
.

Rom
1
,
M.
J.
Blaser
1
, M.
D. Weiden
1
,
1
New York

University School of Medicine, NY;
2

Mount Sinai School
of Medicine
, NY
.


9:4
5
-
10:00 AM

R
EGENRATING ISLET
-
DERIVED III
-
GAMMA REGULATES PULMONARY Th17
IMMUNITY BY ALTERING THE GUT MICROBIOME.

J.
P. McAleer
1
, N.
L.H. Nguyen
1,2
, K.

Chen
1
, D.
M. Ricks
1,2
, M.

Binnie
3
, D.

Sheppard
4
, W.

Ouyang
5
,
Jay K. Kolls
1
*
,

1

Richard King
Mellon Foundation Institute for Pediatric Research, Children’s Hospital of Pittsburgh of
UPMC, Pittsburgh, PA;
2

Department of Genetics, Louisiana State University Health
Sciences Center, New Or
l
eans, LA;
3

U
niversity

of Toronto;
4

University of San Francisco;
5

Genentech.



10:00
-
10:30 AM

......Coffee Break










Wednesday, June 5, 2013

--

Morning


Moderator:
XXXXX


10:30
-
11:05 AM

THOMAS L. PETTY LECTURE

Introduction by Dennis E. Doherty, M.D.

Secretary
-
National Lung Health Education Program

VAMC, Lexington, KY


"ENVIRONMENTAL MICROORGANISMS AND LUNG HEALTH”

Erika von Mutius, M.D., Ph.D.

Professor of Pediatrics

Head, Asthma and Allergy Department

Munich University Children’s Hospital

University of Munich

Munich, Germany

[Sponsored by the National Lung Health Education Program]



11:05
-
11:30 AM

Discussion


11:30
-
11:45 AM

PERINATAL MICROBIAL COLONIZATION
INSTIGATES A LUNG
-
SPECIFIC
IMMUNOREGULATORY PATHWAY THAT PROTECTS AGAINST EXAGGERATED
ALLERGIC INFLAMMATION.

Eva S. Gollwitzer
1,2
*
, B.
J. Marsland
1,2
,
1
Service de
Pneumologie, CHUV, Lausanne, Vaud, Switzerland;
2
Faculty of Biology and Medicine,
University
of Lausanne, Lausanne, Vaud, Switzerland.


11:45
-
12:00


M
ICROBIAL BIOMARKERS INFERRED FROM SHOTGUN METAGENOMIC ANALYSES
OF AGRICULTURAL DUSTS FROM SWINE PRODUCTION AND GRAIN ELEVATOR
FACILITIES.

R. Boissy
3
, D
.
J. Romberger
1, 2
, J
.
A. Poole
2
,
T
.
D
.
LeVan
1,
2, 4
*
,

1
VA Nebraska
Western Iowa Healthcare System, Omaha, NE;

2
University of Nebraska Medical Center,
Pulmonary/Critical Care/Sleep Medicine/Allergy Division;
3
University of Nebraska Medical
Center, Department of Internal Medicine;

4
University of
Nebraska Medical Center,
Department of Epidemiology
, NE
.


12:00
-
1:30 PM

......Lunch


















Wednesday, June 5, 2013

--

Afternoon


Mode
rator: XXXXXX


1:30
-
2:05 P
M


STATE OF THE ART

Rob Knight, Ph.D.


Universit
y of Colorado Boulder



Technologies

and Techniques: Old and New”



2:0
5
-
2:30 PM

Discussion


2:30
-
2:45 P
M

ABUNDANCE OF DNASE
-
SUSCEPTIBLE BACTERIAL DNA FROM DAMAGED CELLS
IN THE LUNGS OF PIGS.

Alejandro A. Pezzulo
*,

B.S. Nassar, N.D. Gansemer, C.J.
Rutland, D.A. Stoltz, J.

Zabner, Department of Internal Medicine, Carver College of
Medicine, University of Iowa, Iowa City, IA.


2:45
-
3:00
PM

COMPARISON OF WHOLE AND ACELLULAR BRONCHOALVEOLAR LAVAGE (BAL)
TO ORAL WASH MICROBIOMES: SHOULD ACELLULAR BAL BE THE STANDARD?
Homer L.

Twigg III
1
*
,

D.E. Nelson
1
,

R.B. Day
1
,

R.L. Gregory
1
,
Q.
Dong
2
,
R. Rong
2
,

K.
Knox
3
,

K. Crothers
4
,

E.

Sodergren
5
,

G.

Weinstock
5
,

1
Indiana University, Indianapolis, IN;

2
University of North Texas, Denton, TX;
3
University
of Arizona, Tucson, AZ;
4
University of
Washington, Seattle, WA;
5
The Genomic Institute at Washington University, St. Louis, MO
.



3:00
-
3:30

PM

......Break


Moderator:
XXXXX


3:30
-
4:05 P
M


STATE OF THE ART

Martin J. Blaser, M.D.


New York University Longone Medical Center



Gut
Microbiome and Effect on the Lung



4:05
-
4:30

PM

Discussion


4:30
-
4:45

PM

DIETARY FIBER SHAPES THE INTESTINAL AND AIRWAY MICROBIOME, ALTERS
DENDRITIC CELL FUNCTIONALITY, AND LEADS TO AN ENVIRONMENT LESS
PERMISSIVE TO ALLERGIC INFLAMMATION.
A.

Trompette
1
, E.

Gollwitzer
1
, L.
P. Nicod
1
,
N.
L. Harris
2
,
Benjamin J. Marsland
1
*
,

1
Faculty of Biology and Medicine, University of
Lausanne, Service de Pneumol
ogie, Lausanne, Switzerland;

2
Globa
l Health Institute,
Lausanne,
Switzerland.


4:45
-
5:00

PM

THE GUT MICROBIOME A
ND THE HYGIENE HYPOT
HESIS OF ALLERGIC DI
SEASE:
IMPACT OF HOUSEHOLD
PETS AND SIBLINGS ON

THE INFANT GUT MICRO
BIOME.

Meghan
B
.

Azad
1
*
,

T
.

Konya
2
, H
.

Maughan
2
, D
.
S
.

Guttman
2
, M
.
R
.

Sears
3
,

A
.
B
.

Becker
4
, J
.
A
.

Scott
2
, A
.
L
.

Kozyrskyj
1

and the CHILD Study Investigators
5
,
1
Department of Pediatrics,
University of Alberta, Canada.
2
University of Toronto,
3
McMaster University,
4
University of
Manitoba,
5
Canadian Healthy Infant Longitudinal Development Study.



5:00

PM

POSTER VIEWING
---

SOCIAL HOUR


Thursday, June 6, 2013

--

Morning


Moderator:
XXXXX


8:00
-
8:35 AM

REUBEN M. CHERNIACK LECTURE


"MUCOSAL IMMUNITY AND THE MICROBIOME


Andrew S. Neish, M.D.

Professor of Pathology and Laboratory Medicine

Experimental
Pathology

Emory University School of Medicine

Atlanta, Georgia


8:35
-
9:00

AM

Discussion


9:00
-
9:15

A
M

POST TRANSPLANT DYNAMICS O
F PULMONARY MICROBIOTA. V.

Poroyko
1
, E.

Semenyuk
2
,

Z.
-
P.

Xu
1
, A.

Sperling
1
, M.
-
L.

Alegre
1
, A.

Chong
1
,
E.

Garrity
1
, S.

White
1
,

Sangeeta Bhorade
1
*
,
1
Department of Medicine, University of Chi
cago, Chicago, IL
;
2
Loyola
University, Chicago
,
IL
.


9:15
-
9:30 AM

THE LUNG MICROBIOME DIFFERS IN ASYMPTOMATIC SUBJECTS AT ELEVATED
RISK FOR FUTURE RHEUMATOID ARTHRITIS COMPARED TO HEALTHY
CONTROLS.
M.
Kristen Demoruelle
*
,

J.M. Norris,

V.M.

Hol
ers,

J.K.
Harris,

K.D. Deane,

University of Colorado School of Medicine, Auro
ra, CO.


9:30
-
10:00 AM

......Coffee Break


Moderator:
XXXXXX


10:00
-
10:35

AM

STATE OF THE ART

Paul Forsythe
, Ph.D.

, M.Sc.



McMaster University



Probiotics and Lung Immune Response








10:35
-
11:00 AM

Discussion


11:00
-
11:15

AM


INULIN TREATMENT LEA
DS TO CHANGES IN GAS
TROINTESTINAL MICROB
IOTA
AND RESOLUTION OF DI
ARRHEA IN RHESUS MAC
AQUES (MACACA MULATT
A)
WITH IDIOPATHIC CHRO
NIC DIARRHEA.
Amir Ardeshir
1
*
,

S.

Sankaran
1,2
, K.

Oslund
1
,
D.
-
H. O'C
onnor
1,2
, N.
W. Lerche
1
, S.

Dandekar
1,2
,

D.

Hyde
1
,
1
California National Primate
Research Center, University
of California, Davis, CA
;
2
Department of Medical
Microbiology and Immunology, University
of California, Davis, CA
.


11:15
-
11:30

AM

INFANT AIRWAY EPITHELIUM IS SUSCEPTIBLE TO PERSISTENT EFF
ECTS OF
TOBACCO SMOKE EXPOSURE:
DIFFERENTIAL REGULATION OF INNATE
RESPONSES TO VIRUS AND BACTERIA.
C.C. Clay
*
,

L.A. Miller, California National
Primate Research Center, University of

California Davis
,

Davis, CA
.



12:0
0
PM

Picnic



T Lazy 7

-

The Ranch



Friday, June 7, 2013

--

Morning


Modera
tor: XXXXX


8:00
-
8:35 AM

GILES F. FILLEY LECTURE

"CIGARETTE SMOKE EFFECT ON INNATE IMMUNE

MECHANISMS WITH ALTERATION IN THE MICROBIOME”

Ilona Jaspers, Ph.D.

Associate Professor of Pediatrics

University of North
Carolina at Chap
el Hill

EPA Human Studies Facility

Chapel Hill, North Carolina






8:35
-
9:0
0 AM

Discussion


9:00
-
9:15 AM

MICROBES AND MICROBIA
L PRODUCTS IN CIGARETTE SMOKE:
IMPLICATIONS
FOR COPD.
Guillina F.G. Bezemer
1,2
*,

É.
Jubinville
2
, E.

Mortaz
1
, A.
D. Kraneveld
1
, J.

Garssen
1
, C.

Duchaine
1
, G.

Folkerts
1
,

1
Utrecht Institute for Pharmaceutical Sciences,
Div
ision of Pharmacology, TIP/TLR F
ramework, Utrecht University,

Utrecht, The
Netherlands;
2
Centre de recherche de I’institut universitaire de cardiolog
ie et de
pneumologie de Québec, Départment de biochimie, de microbiologie et de bioinformatique,
Université Laval, Ste
-
Foy, Québec, Canada.


9:15
-
9:30 AM

NOVOSPHINGOBIUM SSP. ASSOCIATED WITH MORE SEVERE COPD DISEASE IN
HUMANS AND WITH LUNG INFLAMMATION IN
MICE.

A
.
Rutebemberwa
#
*
,

M. Stevens

,
J.K.
Harris

, R.
Tuder
#
,
#
Division of Pulmonary Sciences and Critical Care Medicine,

Department of Pediatrics, Pulmonary Medicine, University of Colorado/Anschutz Medical
Campus, Aurora, Colorado.


9:30
-
10:00 AM

.....
.Coffee Break



Mode
rator: XXXXX


10:00
-
10:35 AM

THOMAS A. NEFF LECTURE


"COPD AND INFECTION:

DISRUPTION OF THE MICROBIOME?”

Sanjay Sethi, M.D., F.A.C.P.

Professor of Medicine

University of Buffalo, SUNY

VA WNY Healthcare System

Buffalo, New York


10:35
-
11
:00 AM

Discussion


11
:00
-
11:15
A
M

THE HOST RESPONSE TO THE LUNG MICROBIOME IN LUNG TISSUE UNDERGOING
EMPHYSEMATOUS DESTRUCTION.

Marc
Sze
1
*
,

P.A. Dimitriu
2
, M. Suzuki
1
, J.E.
McDonough
1
, J.V. Gosselink
1
, W.M. Elliott
1
, W.W. Mohn
2
, D.D. Sin
1
, S.
Hayashi
1
, J.C.
Hogg
1
.
1

UBC James Hogg Research Centre, St. Paul's Hospital / Providence Health Care
-
University of British Columbia, Vancouver, BC, Canada;
2

Department of Immunology and
Microbiology, University of British Columbia, Vancouver, BC, Canada


11:15
-
11
:3
0 AM

THE LUNG MICROBIOME IN MODERATE AND SEVERE CHRONIC OBSTRUCTIVE
PULMONARY DISEASE.

Alexa A. Pragman
1
*,

H.
B
.

Kim
1
, C
.
S. Reilly
1
, C.

Wendt
2
, R
.
E.
Isaacson
1
.
1
University of Minnesota, Twin Cities, and
2
Minneapolis Veterans Affairs Medical
Cent
er
, Minneapolis, MN
.


11:30
-
1:30 PM

......Lunch

Friday, June 7, 2013

--

Afternoon


M
oderator
:
XXXXXX


1:30
-
2:05 PM

ROGER S. MITCHELL LECTURE


“THE MICROBIOME AND ASTHMA”

Homer A. Boushey, M.D.

Professor and Chief of Asthma Clinical Research Center

Division

of Allergy and Immunology

University of California, San Francisco

San Francisco, California


2:0
5
-
2:30 PM

Discussion


2:30
-
2:45 PM

THE AIRWAY MICROBIOME IN SEVERE ASTHMA.
Yvonne J. Huang
1
*
, S.

Nariya
1
, S.
V.
Lynch
2
, J.

Harris
3
, D.

Choy
3
, J
.
R. Arron
3
, H
.

Boushey
1
,

1
Division of Pulmonary, Critical
Care, Allergy & Sleep Medicine, University of California San Francisco;
2
Division of
Gastroenterology, University of California San Francisco;

3
Genentech, South San
Francisco, CA.


2:45
-
3:00 PM

SEGMENTED FILAMENT
OUS BACTERIA COLONIZATION DOES NOT ALTER
RESPONSES TO ALLERGIC AIRWAY SENSIT
IZATION AND CHALLENGE. B.

Scho
tt,
R.A. Martin, J.
L. Ather,

Matthew E. Poynter
*,

Pulmonary Disease and Critical Care
Medicine, Vermont Lung Center, University of Vermont
,

Burlingto
n, VT
.


3:00
-
3:30

PM

......Break


Moderator: XXXXX


3:30
-
4:05 P
M


STATE OF THE ART

Alison Morris, M.D., M.S.


University of Pittsburgh



Heart
-
Lung Interaction Via Infection



4:05
-
4:30

PM

Discussion


4:30
-
4:45

PM

ASPERGILLUS INVASION INCREASES WITH PROGRESSIVE AIRWAY ISCHEMIA.
Joe
L. Hsu
1
*
,

X.

Jiang MD
1
,

M.
A. Khan
1
,

R
.
A. Sobe
l
1
,

K
.
V. Clemon
s
2,3
,

D
.
A. Stevens
2,3
,

M
.
R.
Nicoll
s
1
,

1
VA Palo Alto Health Care System/Stanford University School of Medicine;
2
California Institute for Medical Research;
3
Stanford University School of Medicine
,
Stanford, CA
.


4:45
-
5:
00

PM

LUNG MICROBIOME: ANALYSIS IN LUNG TRANSPLANTATION.
Halvor
McGee
1
*
,

G.
Yung
4
,
A.
Rani
1
,

P.

Kadota
1
,
D.
Perkins
1,2,3
,
P.
Finn
1
, University of
Illinois at Chicago,
Departments of Medicine
1
, Nephrology
2
and Surgery
3
, Chicago, IL, University of California,
San Diego, Department of Medicine
4
, La Jolla, CA.










S
aturday, June 8, 2013

--

Morning


Mod
erator: XXXXX


8:00
-
8:35

AM

STATE OF THE
ART

Susan V. Lynch, Ph.D.



University of California, San Francisco



Viruses and Microbiome Alterations






8:35
-
9:00 AM

Discussion


9:00
-
9:15 AM

LUNG MICROBIOME PRED
ICTS DISEASE PROGRES
SION IN IPF.
MeiLan K Han
1
*,

Y.

Zhou
2
, J.
Erb
-
Downward
1
, N.

Tayob
2
, S.

Murray
2
, K.
R
.

Flaherty
1
, G.
B
.

Huffnagle
1
, F.
J
.

Martinez
1
,
1
Division of Pulmonary & Critical Care, University of Michigan, Ann Arbor, MI;
2
Department of Biostatistics, University of Michigan, Ann Arbor, MI.


9:15
-
9:30 AM

CHARACTERIZATION OF
THE ORAL F
UNGAL MICROBIOTA IN
INDIVIDUALS WITH
HIV AND CHRONIC OBST
RUCTIVE PULMONARY DI
SEASE.

Lijia Cui
1
*
, M.

Rogers
1
, L.

Lucht

1
, A.

Fitch
1
, K.

Saira
1
, C.

Kessinger
1
, L.

Huang
2
, E.

Kleerup
3
, R.

Greenblatt
2
, L.

Kingsley
1
, J.

Wang
1
, N.

Leo
1
,

S.

Fong
2
, J.

Dermand
3
,
A.

Morris
1
, E.

Ghedin
1
,
1
University of
Pittsburgh, Pittsburgh, PA,
2
University of California, San Francisco, San Francisco, CA,
3
University of California, Los Angeles, Los Angeles, CA.


9:30
-
10:00
AM

......Coffee Break


Mode
rator: XXXXXX


10:00
-
10:35

AM

STATE OF THE ART

Michael Surette, Ph.D., B.Sc.



McMaster University



Cystic Fibrosis and the Microbiome






10:35
-
11:00

AM

Discussion


11:00
-
11:1
5 AM

REGULATION OF MICROBIAL POPULUATIONS AND IM
MUNE FUNCTIONS BY
MUC5B. A.
A. Fletcher and
Christopher M.

Evans
*
,

Division of Pulmonary Sciences and
Critical Care Medicine,University of Colorado Denver School of Medicine, Aurora, CO
.


11:15
-
11:3
0

AM

SEROLOGIC EVALUATION OF THE STAGES OF PSEUDOMONAS AERUGINOSA
INFECTION IN CYSTIC FIBROSIS AND RELATIONSHIP TO
HOST MICROARRAY
MOLECULAR SIGNATURE.

Hara
Levy
1,2,3
*,

M. Reske
1,2
, R. Bersie
1,2
, J. Barbieri
4
, S. Jia
5
, M.

Kaldunski
5
, A. Laxova
6

, P.M. Farrell
6
, M.J. Hessner
3, 5, 7
;
1
Department of Pediatrics, Section of
Pulmonary and Sleep Medicine, Medical College of Wisconsin;
2
Children’s Research Institute,
Children’s Hospital of Wisconsin;
3
Human Molecular Genetics Center, Medical College of
Wisconsin, Milwaukee, WI;
4
Department of

Molecular Microbiology, Medical College of
Wisconsin, Milwaukee, WI;
5
Department of Pediatrics, Section of Endocrinology, Medical
College of Wisconsin, Milwaukee, WI;
6
Department of Pediatrics and Population Health
Sciences, UW School of Medicine and Publ
ic Health;
7
Max McGee National Research Center
for Juvenile Diabetes, Department of Pediatrics, Medical College of Wiscons
in, Milwaukee, WI.


1
1:30
-
12
:30

P
M

CONFERENCE SUMMARY

James P. Kiley, Ph.D.

National Heart, Lung, and Blood Institute

National
Institutes of Health

Bethesda, Maryland


1
2:30

PM Discussion and Adjourn


P
OSTER VIEWING
-

SOCIAL HOUR

Wednesday, June 5, 2013

5:00
-
7:00 PM

POSTERS


RATS ARE MORE SENSITIVE THAN LARGER SPECIES TO INHALED ANTIBIOTICS SUCH AS
GENTAMICIN.
Ron Wolff
1
*
,

H.

Conway
2
,
M
.

Reed
3
;
1
RK Wolff


Safety Consulting Inc, Carbondale,
CO;

2
Merck, Summit, NJ;
3
Lovelace Resp Res Inst, Albuquerque, NM.


DECREASED MICROBIAL DIVERSITY PRECEDES VENTILATOR ASSOCIATED PNEUMONIA IN
MECHANICALLY VENTILATED CHILDREN.
P.M. Mourani
*
,
J.K. Harris, J.I. Miller, B.D. Wagner,
M.K. Sontag
,

University of Colorado School of Medicine and Colorado School of Public Health,
Aurora, CO.


BACTERIAL MICROBIOTA DYNAMICS ASSOCIATED WITH EXACERBATIONS OF CHRONIC
OBSTRUCTIVE PULMONARY DISEASE (COPD).
Yvonne J. Huang
1
*
,
S.

Sethi
2
, T
.

Murphy
3
, S
.

Nariya
1
, H
.

Boushey
1
, S
.
V. Lynch
4
,

1
Division of Pulmonary/Critical Care Medicine, Univ. of
California San Francisco;
2
Division of Pulmonary/Critical Care Medicine, Univ. at Buffalo State
University of NY;
3
Department of Medicine, Univ. at Buffalo State University of NY;
4
Division of
Gastroen
terology, Un
iv. of California San Francisco, CA.


CHANGES IN THE LUNG
MICROBIOME FOLLOWING

LUNG TRANSPLANTATION
.

Robert P.
Dickson
*
,

J
.
R. Erb
-
Downward, Z
.

Britt, N
.

Walker, J
.

Curtis, F
.
J. Martinez, G
.
B. Huffnagle, V
.
N.
Lama,

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine,
University of Michigan Med
ical School, Ann Arbor, MI
.


CULTIVABLE MICROBIOME IN CHILDREN WITH CYSTIC FIBROSIS.
M.S. Muhlebach
1
*,

J.E.
Hatch
1
, R.C. Boucher
1

, M. Tunney
2
,
S. Elborn
2
, G. Lavelle
3
, M. Murray
3
, G. McElvaney
3
,
1
UNC
Chapel Hill, NC,
2
Queens University Belfast, UK
3
Royal College of Surgeons, Dublin
,

Ireland.


ANALYSIS OF HUMAN RESPIRATORY TRACT MICROBIAL ECOLOGY BY ION TORRENT 16S
rRNA AMPLICON SEQUENCING.
Gidon

Berger
a, e, &,
*
,

K.
A
.

McCabe
b, &
, C.

Qi
f
, M.

Malczynski

f
,
M.

Rzhetskaya
c,
, E
.

Lecuona
a
, J
.
I
.

Sznajder
a
, R.
G
.

Wunderink

a, #

, M.G.

Hayes
b, c, d, #
,
a
Division of
Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine,
Northwestern University, Chicago, IL;
b
Department of Anthropology, Northwestern University,
Evanston, IL;
c
Division of Endocrinology, Metabolism, and Mole
cular Medicine, Department of
Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL; and
d
Center for
Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL;
e
Department
of Internal Medicine B and Division
of Pulmonary Medicine, Rambam Health Care Campus, Haifa,
Israel,
f
C
linical Microbiology Laboratory, Northwestern Memorial Hospital, Chicago, IL.


A COMPARATIVE ANALYSIS OF BACTERIAL PHYLOTYPES OF THE LUNG MICROBIOTA OF
HEALTHY, IPF AND TRANSPLANTED LUNGS.
John R. Erb
-
Downward
1
*
,

R.
P. Dickson
1
, M.
K.
Han
1
, C.
M. Freeman
2
, Z.

Britt
1
, N
.
Walker
1
, V.
N. Lama
1
, J.
L. Curtis
2
, F.
J. Martinez
1
, G.
B. Huffnagle
1
,
1
Division of Pulmonary Medicine and Critical Care, Department of Internal Medicine, University of
Michigan Health System, Ann Arbor MI,
2
Pulmonary & Critical Care Medicine Section, VA Ann Arbor
Health System, Ann Arbor, MI.







P
OSTERS



Wednesday,
June 5, 2013

-

continued


IMMUNE RESPONSE INDUCED PULMONARY HYPERTENSION


ROOTS IN

AN ANCIENT
VASCULAR MICROBIOME
?

S.
-
H.

Park,
Gabriele Grunig
*
. Environmental Medicine, NYU Medical
Center, Tuxedo, NY.


ISOLATION AND CHARAC
TERIZATION OF A NOVE
L PSEUDOMONAS SPECIE
S FROM AN
INDIVIDUAL WITH CHRO
NIC RESPIRATORY DISE
ASE.
Brittan S Scales
*,

J.
R
.

Erb
-
Downward
,
F.
J
.

Martinez
, G.
B
.

Huffnagle, Division of Pulmonary & Critical Care Medicine, University of
Michigan,

Ann Arbor, MI.


DETECTION OF LUNG MICROBIOTA BY NEXT
-
GENERATION SEQUENCING IN ACUTE BURN
INHALATION INJURY.
Dana M. Walsh
1
*,

S.

Yourstone
2,3
, D.
S. Lundberg
2,4
, J.
J. Kahle
8
, S.
D.
McCullough
8
, C.

Jones
3
, J.
L. Dangl
2,4,
, T.
L. Noah
5,6
, S.
W. Jones
7
, I.
Jaspers
1,6,
,

D.

Diaz
-
Sanchez
1,8
,

1
Curriculum in Toxicology,
2
HHMI and Department of Biology,
3
Curriculum in Bioinformatics and
Computational Biology,
4
Curriculum in Genetics and Molecular Biology,
5
Center for Environmental
Medicine, Asthma and Lung Biolo
gy,
6
Department of Pediatrics,
7
Department of Surgery,
1
-
7
University
of North Carolina, Chapel Hill, NC
8
United States Environmental Protection Agency, Office of
Research and Development, Research Triangle Park, NC.


SINUS MICROBIOME IN HEALTH AND DISEASE:

CHRONIC RHINOSINUSITIS.
Vijay R
Ramakrishnan
1
*
, D.
N
.

Frank
2,3
,

1
Department of Otolaryngology, University of Colorado, Aurora CO;
2
Division of Infectious Disease, University of Colorado, Aurora CO;
3
Microbiome Research
Consortium, University of Colorado,
Aurora CO.


A
NALYSIS OF THE COLON CANCER MICROBIOME: A MULTIPLATFORM APPROACH.
K. Leigh
Greathouse
1,2
*
, C.

Harris
1
,
1
Laboratory of Human Carcinogenesis, Center for Cancer Research,
National Cancer Institute, Bethesda, MD;
2
Cancer Prevention Fellowship, Di
vision of Cancer
Prevention, NCI, Bethesda, MD.


CHARACTERIZATION OF THE LUNG MICROBIOME OF POLYMERIC IMMUNOGLOBULIN
RECEPTOR (pIgR) NULL MICE.
B.W.
Richmond
ⱡ1
*
, R.M.
Brucker
ⱡ2
, V.V.
Polosukhin
1
,

S.R.
Bordenstein
2,3
,

T.S.
Blackwell
1,4
,

Vanderbilt
University, Nashville, TN.


DETERMINATION OF THE LUNG MICROBIOME OF HIV
-
1 PATIENTS WTH AND WITHOUT
PULMONARY HYPERTENSION: CORRELATION ANALYSIS TO UNIQUE NEF VARIANTS .
Adela
Cota
-
Gomez
1
*,

C
.

Lozupone
2
, A
.
P. Fontenot
1
,
R. Knight
2
,

S.C. Flores
1
,

1
University of Colorado
Anschutz Medical Campus,

Aurora, CO,

2
University of Colorado, Boulder
, CO
.


THERE IS MORE TO MICROBIOMES THAN BACTERIA: DETERMINATION OF THE HUMAN
PLASMA VIROME IN HIV
-
ASSOCIATED PULMONARY HYPERTENSION.
Adela Cota
-
Gomez
*
, R.
Schoen,

K. L. Jones, S.
C. Flores. University of Colorado Anschutz Medical Campus
, Aurora, CO.