Thierry Lesnik Doctor in Microbiology - ProZ.com

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12 Φεβ 2013 (πριν από 4 χρόνια και 8 μήνες)

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Thierry Lesnik

Ph D in Molecular Biology


_________________________________________________________________



Nationality

: french

born the 26 august of 1962 in Armentières (59, Nord, France)

No military obligations

Single


Permanent address :

Le Claud

24210 Brouchaud France

Tel / fax : (33) 05 53 06 35 32

Email : thierry.lesnik@wanadoo.fr


Translation : from english to french

Domains : medicine, pharmacology, biotechnology, biology, chemistry

N° URSSAF : 240 299197352

rate per 1000 source words : 68 €, per 1000 target words 60 €



_________________________________________________________________


Diploma :


-

1994 French pHD in Genetics and Physiology of Microorganisms


-

1986 DEA in Biotech
nology



Competence domains :


Microinformatics
-

Works on Macintosh (Macwrite II, Word6, Excel4, CricketGraph)
-

programming in BASIC
-

use of Internet


Statistical treatment of data (Statview II, Statistica)


Theory and practice of molecular biology of P
rokaryotes and Eukaryotes
-

Biochemistry
-

Enzymology
-

Biotechnology
-

Molecular toxicology


Foreign languages :


-

english : fluent (read, written, spoken; 1 year in the USA)







Professional training :


2008: translation of patents, scientific articl
es and technical guides in the field of
chemistry and life sciences


2007: translation of patents, scientific articles and technical guides in the field of
chemistry and life sciences


2006: translation of patents, scientific articles and technical guides
in the field of
chemistry and life sciences


2005: translation of patents, scientific articles and technical guides in the field of
chemistry and life sciences.


2004

: translation of patents, scientific articles and technical guides in the field of
chemis
try and life sciences.


2003: translation of patents, scientific articles and technical guides in the field of
chemistry and life sciences. Translation of the book "Essential Developmental
Biology", Slack.


2001
-
2002: translation of patents, scientific art
icles and technical guides in the field of
chemistry and life sciences.



2000 : translation (english to french and french to english) of biotechnology patents,
research articles in pneumology, nutrition, pharmacology, guides of medical software,
CD ROM

presentation of the Ecole Polytechnique, texts for the french review La
Recherche, localisation in english of a french web site



1999 : translation of texts (from english to french and french to english) in
“Advances in Molecular Toxicology”
(1999),
volume 2.



1998 : translation of texts (from english to french and french to english) in
“Advances in Molecular Toxicology”
(1998), volume 1.



1999 : taking part in the “Second European Workshop in Molecular Toxicology”, in
Paris.



1994
-

1999 : post
-
doctoral researcher at the laboratory of Structure and Dynamics
of the Genome of Dr C. Reiss.

-

study of the chloramphenicol acetyl transferase enzyme and influence of
synonymous codon mutations on the folding of the protein during its transla
tion.

-

study of the prion
-

like URE2p protein of Saccharomyces cerevisiae and analysis of
its translational expression and its conformation in various expression systems.



1991
-

1994 : researcher at the laboratory of Structure and Dynamics of the

Genome of Dr C. Reiss
-

thesis subject:
exploitation of a database of Escherichia
coli. Analysis of the composition of genes and their translation



1989 : training at the laboratory of biochemistry of Dr JA Traugh, at the University
of California
-

Riverside
-

subject :
study of the lranscriptional expression of the type II
Casein
-
kinase

of calf live
r


1987 : training at the laboratory of Structure and Dynamics of the Genome of Dr C.
Reiss at the Institute Jacques Monod in Paris
-

subject :
stud
y of the pause sites of
RNA polymerase during transcription



1986 : DEA training at the laboratory of Structural Biophysics of Dr JG Brahms at
the Institute Jacques Monod in Paris
-

UT Compiegne fellowship
-

subject :
building of
an affinity column

for the purification of the glucocorticoid receptor


Publications :


-

9 articles, in annex



Extraprofessional activities :


-

contemporary litterature, jazz, sport


Referees :


-

french translation agency Traductis

-

french translation agency Translant
ic


















ANNEX



Publications :




Modeling and theory :


-

Lesnik T. & Reiss C. (1996),“A method to detect transmembrane segments at the
nucleotide level” , Biochem. Mol. Biol. Internat., 38, 937
-
955.


-

Solomovici J., Lesnik T. & Reiss C. (199
7), “Does
Escherichia coli

optimize the
economics of the translation process ?”, J. theor. Biol. , 185, 511
-
521.


-

Lesnik T. & Reiss C. (1998), “Detection of transmembrane helical segments at the
nucleotide level in eukaryotic membrane protein genes”, Bio
chem. Mol. Biol. Internat.,
44, 471
-
479.


-

Lesnik T., Solomovici J, Deana A., Ehrlich R. & Reiss C. (2000), “Ribosome traffic
and regulation of gene expression in
Escherichia coli

» J. of theor. Biol., 202, 175
-
185.


-

Reiss C., Lesnik T., Parvez H., Parvez

S. and Ehrlich R. (2000), Conformational
toxicity and sporadic conformational diseases, Toxicology, 153, 115
-
121.



Experimentation :


-

Komar A., Lesnik T., Ehrlich R. & Reiss C. (1997), “Effects of synonymous codon
usage on ribosome traffic and protein
synthesis”, Protein Science, 6 (sup2), 102.


-

Komar A., Lesnik T., Cullin C., Guillemet E., Ehrlich R. & Reiss C. (1997), “
Differential resistance to proteinase K digestion of the yeast prion
-

like (Ure2p)
protein synthesized in vitro in wheat germ extr
act and rabbit reticulocyte lysate cell
-

free translation systems”, FEBS lett., 415, 6
-
10.


-

Komar A., Lesnik T., Cullin C., Reiss C. & Altmann M., (1999) “Alternative initiation
of the
Saccharomyces cerevisiae

Ure2 prion
-
like protein : implications for
the prion
model in yeast “, Third european symposium of the protein society, Garmisch
-

Partenkirchen, Germany, 19
-
22 septembre


-

Komar A., Lesnik T., Cullin C., Reiss C. & Altmann M., “Alternative initiation of
translation of the yeast Ure2 prion
-

like
protein”, submitted.


-

Komar A., Lesnik T. & Reiss C. (1999), “Synonymous codon substitutions affect
ribosome traffic and protein folding during in vitro translation”, FEBS Lett., 462, 387
-
391.