sample exam questions for systems bioinformatics - Biology ...

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OLLSCOIL NA hÉIREANN MÁ NUAD


THE NATIONAL UNIVERSITY OF IRELAND
MAYNOOTH




B.SC. DEGREE (COMPUTATIONAL BIOLOGY &
BIOINFORMATICS) EXAMINATION




SAMPLE

2004
-
2005





BI419 BIOINFORMATICS 1





Prof. R. O’Kennedy, Prof K. Ohlendieck










Answer
ALL

questions in Section A and
ONE

from Section B.




Time for examination:
2
HOURS.



BI419 Bioinformatics Programming

Page 1 of 1

Sample 2005

SECTION A (50 marks)





Answer
ALL

questions in this section.



All questions in this section carry equal weight.



1.

How are amino acids classified and what this classification

is important for,
from the evolutionary and structural points of view?


2.

How would explain that a single molecule such as a molecular chaperone is able
to fold 2500 completely different proteins in proteobacterium
Escherichia coli


3.

What makes a protein a g
ood candidate for crystallization and structure
analysis?


SECTION B (50 marks)





Answer
ONE

question from this section.



4.

Please explain and describe the main characteristics of secondary structures of
proteins, mainly the

-
helix protein structure and

-
sheet structure.


5.

Please write an assay on the evolution of protein structure