cs’ Seminar Lesson Plan Number 2
Biology, AP Biology, Anatomy & Physiology,
The Nervous System; Bioinformatics
Exploring the Neuroscience of the Human Brain Using Bioinformatic T
The field of neuroscience is rapidly growing and information generated from research
being made available electronically on
. To utilize this information in a meaningful way
and relational data
bases are critical to anyone who wishes to examine information related to
of interest. One new site that has been developed is entitled
“Genes 2 Cognition”
. This is a media
containing information on Human Brain Disorders, Cognitive P
rocesses, Research Approaches, Protein
Interactions and an interactive 3
D Model of the Human Brain. Each of these areas also provides additional links to
bioservers (NCBI, OMIM, Estrez, PubMed, PDB, etc.) for further exploration.
What is the structure and function of the nervous system?
: How do you use bioinformatic relational databases to explore biological molecules?
To begin this activity students will log on to the Genes 2 Cognition web
site at the following address:
To become familiar with the website and its various components they should watch the tutorial by clicking the
located on the top menu bar.
they are familiar with the general layout and operation of the site they should explore the
section by viewing the related subway lines for Genes, Biochemicals, Cells, Brain Anatomy and Cognition.
located under the
Protein Interaction Database
students should select a molecule for further study. Using the
provided for various
(OMIM, NCBI, Allen Brain Atlas, Ensemble,
Entrez, etc. )
complete their worksheet with information on the molecule’s name, identification
number, species, chromosome number and locus, a description of its physiology along with identifying specific
regions of the brain where they interact. These regions should b
e explored using the
component of the website
Students will record the results of their search in the appropriate section(s) of their
worksheet and answer the concluding questions.