Role of IT in Bioinformatics

underlingbuddhaΒιοτεχνολογία

2 Οκτ 2013 (πριν από 4 χρόνια και 9 μέρες)

104 εμφανίσεις

Role of IT in
Bioinformatics


Naveena.Y

What is bioinformatics ?



Study of Information content and information
flow in biological systems and processes



Definition varies depending upon the domain of
person who is giving the definition

What was the reason
behind the emergence of
a separate domain,
bioinformatics ?


Brief History


Insulin


1956


Yeast trna


1960’s


PDB


1972


Swissprot


1986


Human Genome


Initiated


1988


Completed


26
th

Jun 2000

Where does the data come
from?

Wet Lab Research

Database 1

Ex : Genbank

Database 2

Ex : Swissprot

Database 3

Ex : Interpro

Publish

Primary

Secondary

Composite

Central Dogma of Life

What is their in each of this?


DNA


A,C,T,G


RNA


A,C,U,G


Protein





AUG
ACG
AGA
AGG
AGUAGAAGUAG

M

V

Codon Table

Protein Structure

Primary

Secondary

Teritary

Quarternary

IT is used in different areas


Functional Genomics


Proteomics


Drug Discovery


Plant Biotechnology


Molecular Modeling


Challenges


Protein Structure Prediction



RNA Structure Preditction



Drug Discovery



Pharmacogenomics


Questions ?