INSTITUTE OF MOLECULAR BIOLOGY & BIOTECHNOLOGY THE ...

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IMBB,UOL

INSTITUTE OF MOLECULAR BIOLOGY & BIOTECHNOLOGY

THE UNIVERSITY OF LAHORE

Sample Test for B
S

(Biochemistry/Molecular Biology/Biotechnology/Microbiology)

(Fall, 2011)

Name:_______________


Roll. No.______________

Total marks: 50




Time Allowed: 1 Hr.

Part I: LANGUAGE

A.

.
In each of the following questions, pick the one most nearly opposite in meaning

1.

Vicious

a)

depraved

b)

moral

c)

profligate

d)

iniquitous

e)

ferocious


2.

Heterogeneous

a)

uniform

b)

dispersed

c)

abridged

d)

mixture

e)

simple


3.

Redundant

a)

insufficient

b)

expanded

c)

profound

d)

numerous

e)

verbose


4.

Sedulity

a)

silent

b)

justify

c)

futility

d)

carelessness


2


e)

verbosity


B.

For each blank, pick the word or set of words that best reflects the sentence’s meaning.


5.

A
judgment made before all the facts are known must be called_____________.

a)

harsh

b)

deliberated

c)

sensible

d)

premature

e)

fair


6.

The Supreme court reversal of its previous ruling on the issue of provincial rights
______________________ its reputation for
________________.

a)

Sustained …..inconsistency

b)

Compromised…..consistency

c)

Maintain…..fallacy

d)

Spoiled……flexibility

e)

Dispelled…vacillation


7.

The study on Pseudomonas is so ___________________that it leaves no part of life
cycle of this notorious pathogen.

a)

compreh
ensive

b)

haphazard

c)

sporadic

d)

prolific

e)

clean


8.

As the French archaeologist expected, living condition in Gandhara civilization were
_______________________worse than those of days,

a)

broadly

b)

astonishing

c)

significantly

d)

begrudgingly

e)

awful

Part II
: SCIENTIFIC

9. When

two amino acids joined, the alpha
-
amino group of one amino acid act as nucleophile to displace
the hydroxyl group of another amino acid which leads to formation of a peptide bond. This joining is
achieved by a reaction mechanism called

(A) electrophilic

(B) neurtrophilic

(C) condensation


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(D) amino acid substitution

(E) hydrolysis


10. The peptide bond in proteins is considered to be

(A) non planar

(B) linear

(C) planar

(D) non rigid

(E) hydrophobic



11. Alpha helices are found in proteins in

(A)
right handed form

(B) left handed form

(C) right and left handed forms

(D) in parallel form

(E) in antiparallel form


12. Secondary structure in proteins are predominantly stabilized by

(
A) covalent interaction

(B) hydrophobic interactions

(C) hydrogen b
onding

(D) Vander wall forces

(E) dipole interactions


13. Which of the following residues usually occur in beta turns?

(A) proline and glycine

(B) alanine and lysine

(C) valine and cysteine

(D) threonine and serine

(E) glutamate and aspartate


14. Two
forms of beta
-
sheets, parallel and antiparallel are generally found in proteins. Which one is
thermally more stable?

(A) parallel beta sheet

(B) antiparalell beta sheet

(C) equally stable

(D) cannot be compared on the basis of stability


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(E) none of the sta
ble


15. Determination of protein 3
-
dimensional structure is important to elucidate the function of proteins
at molecular level. Which of the following techniques can be used for structural studies?

(A) Nuclear magnetic resonance spectroscopy

(B) X
-
ray cry
stallography

(C) Electron diffraction

(D) A and B

(E) A, B and C


16. How many residues generally contribute to a turn in the helix

(A) 3.6

(B) 5.4

(C) 4.5

(D) 2.5

(E) A and C


17. The secondary structure of a polypeptide chain can be defined if ________
_____ angles are known
for all amino acids in that chain.

(A) Phi and Psi

(B) side chain

(C) amide bond

(D) A and B

(E) A, B and C


18. The function of the larynx, which is placed above the trachea, is to

Produced sound

Absorb O2

Send out CO2

Prevent dust

Sneezing


19. The inflammation of the respiratory path causes

a)

Thrombosis

b)

Bronchitis

c)

Catarrh

d)

Sneezing

e)

Cancer


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20. The muscles that are responsible for breathing are

a)

Voluntary

b)

Involuntary

c)

Cardiac

d)

Skeletal

e)

.None of these


21
. In Michaelis
-
Menten

equation, the substrate concentration at which initial velocity is equal to half of
the maximum velocity is called

a)

K
d

b)

K
m

c)

V
º

d)

K
cat

e)

K
i


22
. The by
-
product of photosynthesis is…………………….

a)

Oxygen

b)

Carbon
-
dioxide

c)

Nitrogen

d)

Hydrogen

e)

Sulphur

23
. The best way to
compare the catalytic efficiencies of different enzymes or the turnover of different
substrates by the same enzyme can be done by comparing

a)

Specificity constant

b)

Dissociation constant

c)

Association constant

d)

Michaelis
-
Menton constant

e)

None of the above



24
.Nitrosomans is ……………

a)

Nitrifying bacteria

b)

Sulphur bacteria

c)

Ammonifying bacteria

d)

Hydrogen bacteria

e)

Denitrifying bacteria


25
. A raised level of calcium in the blood (hypercalcaemia)

a)

Causes increased excitability of nerve and muscle

b)

Is caused by chronic rena
l failure

c)

Increases the risk of stone formation in the urinary tract


6


d)

Is a consequence of decreased parathyroid activity

Is a consequence of a reduction in the plasma protein level


26
. Two families of monosaccharides are ____________.

A.

Alpha and beta sheets

B.

Hydrophobic and hydrophilic

C.

Aldoses and ketoses

D.

Deoxyriboses and riboses

E.

Hydroxyls and Carboxyls


27

. Two sugars that differ only in the configuration around one carbon atom are
called_______________.

A.

Monomers

B.

Epimers

C.

Dimers

D.

Homomers

E.

Hemimers


28
. In describing disaccharides or polysaccharides, the end of a chain with a free anomeric carbon is
commonly called the _____________.

A.

Oxidizing end

B.

Reducing end

C.

Oxidizing and Reducing end

D.

Caroxyl end

E.

Amino end