Core Facilities overview - The University of Toledo

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1 Οκτ 2013 (πριν από 3 χρόνια και 11 μήνες)

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Core Facilities


Center for Materials and Sensor Characterization

The UT Center for Materials and Sensor is a multi
-
user facility established for
microstructural, chemical and thermal characterization in the fields of material,
biological and
environmental scien
ces. The facility houses "state
-
of
-
the
-
a
rt" electron
microscopes and numer
ous other characterization instruments
.

The
c
enter provides
tools for developing new technologies and support for the current characterization
needs.

The
c
enter of
fers professionally managed instrumentation located in three adjacent
laboratories. The heart of the
c
enter is the following three electron microscopes located
in the Electron Microscopy and Materials Characterization Laboratory.



Scanning Electron Microsco
pe (SEM)



Scanning Transmission Electron Microscope (STEM)



Dual Beam Environmental SEM and focussed ion Beam (ESEM/FIB)

Advanced Microscopy and Imaging Center

The University of Toledo Advanced Microscopy & Imaging Center on the Health
Science Campus is a 3,
000 square foot facility designed to bring together advanced light
and fluorescence microscopy systems and “state of the art” image analysis software to
perform biomedical research
.
The
c
enter consists of a 1,000 square foot
g
eneral
m
icroscopy
l
aboratory w
ith 12 separate workstations

housing individual, computer
-
based microscopy systems.


The center also includes an 800 square foot,
t
issue
-
culture
m
icroscopy
laboratory with 6 separate workstations

for microscopy systems dedicated
to the study of living cell
s, along with complete culture facilities and a cryogenic storage
system.

The current systems running in the facility include:


-
D Construction



-
phot
on Microscopy in Real
-
Time








Flow Cytome
try Core

the Flow Cytometry Core Facility provides access to instrumentation, assistance, and
guidance, and offer information on current cytometric methods and applications as well
as on dyes, cytometric bead arrays, multi
-
color
panel kits, and other reagents.
The Flow
Core provides high
-
speed cell analysis for
an extensive array of biological processes.

In addition the Flow Core also offers high
-
speed cell sorting. This can be used to
isolate/separate cell types (or vesicular
bodies), rare populations, as well as specific
clones post
-
transfection for further cell culture or analysis/experimentation

if a
population can be labeled, distinguished, and gated, it can be sorted.

Genomics Core

The Bioinformatics and Proteomics/Genomic
s Program's Genomics Core Laboratory
(GCL)

provides students and researchers with the advanced analytical tools and
approaches needed for state
-
of
-
the
-
art biomedical research.


The Nuclear Magnetic Resonance Facility

The NMR core has four NMR and one ESR
spectrometer located in proximity to
chemistry, biological sciences and pharmacy labs.
The Bruker Avance III 600Mhz
spectrometer with Cryoprobe and a Z gradient was installed
in early 2012
. This
spectrometer also has Solid state NMR capabilities. It has a
4 mm Top
-
loading DVT
Multinuclear Double Resonance MAS probe tunable from 15N to 31P. The active
volume is 50 microliter and maximum spinning speed is 15 kHz. VT range
-
50
o
C to
+120
o
C.