Additional information - TeachLine

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1 Οκτ 2013 (πριν από 3 χρόνια και 6 μήνες)

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Laboratory Profile

Principal Investigator:

Liran Carmel

Computational biology, bioinformatics and molecular evolution

Location:

Silberman

building
, 3
rd
. floor

Room
2
-
3
42

Communication:



E.Mail
:

carmell
@
cc.
huji.ac.il



Phone
:

6585
103



Web:

http://carmelab.huji.ac.il

Brief description of research
:

My lab

is purely computational, and studies a wide
range of topics in comparative genomics and molecular evolution. We currently
focus on topics such as ide
ntifying noncoding functions of introns, identifying the
relations between introns in 3’UTRs and nonsense
-
mediated decay (NMD),
identifying disease
-
causing genetic variations, studying forces designing codon
usage bias in mammals, finding novel splicing re
gulatory elements, reconstructing
evolutionary histories, and understanding the Neanderthal genome.

Techniques
: Computational biology and bioinformatics. We use many
computational techniques, depending on the specific question that we study. We
analyze a l
ot of deep sequencing data, including whole genome sequencing, whole
exome sequencing, and RNA
-
seq.

Proposed Research Projects:



Topic 1: Studying whether intron jumping had been a major evolutionary force that can
explain peculiarities in intron
-
exon gene
structure evolution.



Topic 2: Studying intron
-
related features of long noncoding RNAs (lncRNAs).