Current and Future Trends in Indsutry - Stan Mainzer - PIEP

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September 27
th
, 2012

Stan Mainzer

DuPont Industrial Biosciences

“Current and Future Trends in
Industry”

“WHITE BIOTECHNOLOGY”

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Who is DuPont Industrial Biosciences?

Genentech


&

&

DuPont Industrial Biosciences

&

1982 to 2012: 30 years of industrial biotechnology

=

2

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What is Industrial or White Biotechnology?

“The application of biotechnology for industrial applications…” (Wikipedia)

3

Key Market Segments in Our Business

4

Bioactives

Biomaterials

Biorefineries

P
roducts

End use markets

Enzymes, proteins,
peptides

Food and beverages,
feed, cleaning, paper,
personal care

Biochemicals


Biomaterials

Carpet,
textiles,
automotive

Ethanol

Biobutanol

Bioprocessing aids

Fuels, carbohydrates

Agriculture
and
Nutrition

Industrial
Biosciences

Advanced
Materials

Bioactives

Biorefineries

Biomaterials

Core

Core Elements

•
Renewable,
biobased
inputs

•
Design and operation of cell factories

•
Deliver enhanced process and product sustainability

Processing

•
Extraction

•
Conversion

•
Separation

Biotechnology

•
Genomics

•
Molecular biology

•
Fermentation

Health

•
Nutrition science

•
Immunology

•
Microbiology

Application

•
Food science

•
Formulation
knowledge

•
Sensory science

5

DuPont Nutrition & Health

Industry Leading Science

Digestive

Immune

Weight

Bone

Heart

Oral

Sports

Focused on Three Biobased Segments

Serving a diverse set of customers

6

Biobased Products

End use markets

Bioactives

Biomaterials

Biorefineries: Biofuels

Enzymes, proteins,
peptides

Food and beverages,
feed, cleaning, paper,
personal care

Biochemicals


Biomaterials

Carpet,
textiles,
automotive

Ethanol

Biobutanol

Bioprocessing aids

Fuels, carbohydrates

Bio/chemical

transformation

Biomass

Sugars

Bio/chemical

transformation

Our Competitive Advantage

Carbon Sources

Conversion

Starch


Bakery Enzymes

8

Amylases / Starch Acting Enzymes

Pullulanase

b
-
amylase

a
-
amylase

a
-
amylase

Amyloglucosidase

Pullulanase

Amyloglucosidase

9

Amylases as Anti
-
staling Agent

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C
-
OCH
2
CH
2
CH
2
O
)
-

O

-
(
-
C

O

n


+


DMT / TPA

•

Unique polymer with


versatile properties

•

37wt% renewable content

Catalyst


1,3
-
propanediol

Sorona
® polymer


DuPont™
Sorona
® Bio
-
Based PTT Polymer


Bio
-
PDO™

PTT =
Polytrimethylene

Terephthalate

10


DuPont™
Sorona
®
-

Carpet & Apparel
Applications

•

Stain Resistance “Engineered Into” the fibers

•

Resiliency

•

Bright color & Infinite Color Choices

•

Superior Soft Touch

•

Bio
-
PDO™Strong

Environmental Benefits


Residential Carpet


Commercial Carpet

Aotomotive

Carpet Apparel

11

DuPont and Goodyear jointly develop BioIsoprene™ Process



DuPont
and The
Goodyear Tire
& Rubber


Company: an integrated process
to,


manufacture BioIsoprene™ product at industrial scale

A collaborative research initiative

Joint multimillion
-
dollar investment

BioIsoprene™ product is a bio
-
based, renewable


alternative to the petroleum
-
based isoprene

BioIsoprene™ is a
“
business platform chemical
”

DuPont
will lead commercial development

Concept tire
–

not
available to consumers

17

Biomaterials

12

DuPont Confidential

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A
BioIsoprene
™ Cell Factory

Multiple feedstocks possible

Two feeder pathways to isoprene precursor

Isoprene synthase


C6
►
3C

(C5)

3C
►
2C

16C
►
2C

Isoprene

Synthase

Isoprene

Recovery

Glucose

Sucrose /

Biomass

Glycerol

Plant Oils

MEP Pathway

MVA Pathway

Cells

Conceptual View of
the Isoprene Cell
Factory

13

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Enabling the
Biochemicals & biofuels industries
through
our unique expertise

14

The Overall Design of the CE
Biorefinery

15

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An Expanding Need for Industrial Biotechnology

We are living in an age of
climate
c
hange
and
environmental decline.

The
earth
is
warming.

Clean air and water are becoming more
scarce.

Fossil fuel demand is increasing and its use is accelerating
climate
change.

16

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One Idea: GNext

17


A
n open innovation engine
designed to help companies

developing solutions for air,
water and bio
-
energy.


L
everages
Genencor’s

core
competencies in the discovery,
engineering, production and
supply of enzymes, proteins and
microorganisms
–

at large
-
scale
and a low price
-
point.

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Addressing society’s big needs

Improving air quality

•
Cleaning the Air

•
Preventing Pollution





18

Clean water for everyone

•
Potable, Industrial or
Agriculture Water

•
Pollution prevention or
remediation

Sustainable bio
-
energy

•
Affordable energy

•
Sustainable energy

•
Secure

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Who should partner with us

19

Two

Three


One

If you are developing
a solution for air,
water or bio
-
energy.

And require an
enzyme, protein or
microorganism as key
element of that
technology.

Talk with us.

Together we can accomplish what
can’t be don
e

alone. Thank you.

gnext.genencor.com

|
gnext@danisco.com

Copyright © 2012 DuPont or its affiliates. All rights reserved. The DuPont Oval Logo, DuPont™
Danisco
®
and all products denoted with ™ or
®

are
registered trademarks or trademarks of E. I. du Pont de Nemours and Company or its affiliates.

21

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Food

Health


Need to increase food supply
significantly


Rising raw material prices


Need for
affordable and
sustainable food


Trend for natural, clean label
product


Twin challenges of obesity

and aging


Chronic disease


Food safety and pandemics


Demand for healthy foods

We will be the premier specialty food ingredient and food safety leader

Nutrition

Safety

Sustainability

Nutrition & Health: Business Opportunity

22