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September 27
th
, 2012
Stan Mainzer
DuPont Industrial Biosciences
“Current and Future Trends in
Industry”
“WHITE BIOTECHNOLOGY”
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Who is DuPont Industrial Biosciences?
Genentech
&
&
DuPont Industrial Biosciences
&
1982 to 2012: 30 years of industrial biotechnology
=
2
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What is Industrial or White Biotechnology?
“The application of biotechnology for industrial applications…” (Wikipedia)
3
Key Market Segments in Our Business
4
Bioactives
Biomaterials
Biorefineries
P
roducts
End use markets
Enzymes, proteins,
peptides
Food and beverages,
feed, cleaning, paper,
personal care
Biochemicals
Biomaterials
Carpet,
textiles,
automotive
Ethanol
Biobutanol
Bioprocessing aids
Fuels, carbohydrates
Agriculture
and
Nutrition
Industrial
Biosciences
Advanced
Materials
Bioactives
Biorefineries
Biomaterials
Core
Core Elements
•
Renewable,
biobased
inputs
•
Design and operation of cell factories
•
Deliver enhanced process and product sustainability
Processing
•
Extraction
•
Conversion
•
Separation
Biotechnology
•
Genomics
•
Molecular biology
•
Fermentation
Health
•
Nutrition science
•
Immunology
•
Microbiology
Application
•
Food science
•
Formulation
knowledge
•
Sensory science
5
DuPont Nutrition & Health
Industry Leading Science
Digestive
Immune
Weight
Bone
Heart
Oral
Sports
Focused on Three Biobased Segments
Serving a diverse set of customers
6
Biobased Products
End use markets
Bioactives
Biomaterials
Biorefineries: Biofuels
Enzymes, proteins,
peptides
Food and beverages,
feed, cleaning, paper,
personal care
Biochemicals
Biomaterials
Carpet,
textiles,
automotive
Ethanol
Biobutanol
Bioprocessing aids
Fuels, carbohydrates
Bio/chemical
transformation
Biomass
Sugars
Bio/chemical
transformation
Our Competitive Advantage
Carbon Sources
Conversion
Starch
Bakery Enzymes
8
Amylases / Starch Acting Enzymes
Pullulanase
b
-
amylase
a
-
amylase
a
-
amylase
Amyloglucosidase
Pullulanase
Amyloglucosidase
9
Amylases as Anti
-
staling Agent
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C
-
OCH
2
CH
2
CH
2
O
)
-
O
-
(
-
C
O
n
+
DMT / TPA
•
Unique polymer with
versatile properties
•
37wt% renewable content
Catalyst
1,3
-
propanediol
Sorona
® polymer
DuPont™
Sorona
® Bio
-
Based PTT Polymer
Bio
-
PDO™
PTT =
Polytrimethylene
Terephthalate
10
DuPont™
Sorona
®
-
Carpet & Apparel
Applications
•
Stain Resistance “Engineered Into” the fibers
•
Resiliency
•
Bright color & Infinite Color Choices
•
Superior Soft Touch
•
Bio
-
PDO™Strong
Environmental Benefits
Residential Carpet
Commercial Carpet
Aotomotive
Carpet Apparel
11
DuPont and Goodyear jointly develop BioIsoprene™ Process
DuPont
and The
Goodyear Tire
& Rubber
Company: an integrated process
to,
manufacture BioIsoprene™ product at industrial scale
A collaborative research initiative
Joint multimillion
-
dollar investment
BioIsoprene™ product is a bio
-
based, renewable
alternative to the petroleum
-
based isoprene
BioIsoprene™ is a
“
business platform chemical
”
DuPont
will lead commercial development
Concept tire
–
not
available to consumers
17
Biomaterials
12
DuPont Confidential
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A
BioIsoprene
™ Cell Factory
Multiple feedstocks possible
Two feeder pathways to isoprene precursor
Isoprene synthase
C6
►
3C
(C5)
3C
►
2C
16C
►
2C
Isoprene
Synthase
Isoprene
Recovery
Glucose
Sucrose /
Biomass
Glycerol
Plant Oils
MEP Pathway
MVA Pathway
Cells
Conceptual View of
the Isoprene Cell
Factory
13
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Enabling the
Biochemicals & biofuels industries
through
our unique expertise
14
The Overall Design of the CE
Biorefinery
15
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An Expanding Need for Industrial Biotechnology
We are living in an age of
climate
c
hange
and
environmental decline.
The
earth
is
warming.
Clean air and water are becoming more
scarce.
Fossil fuel demand is increasing and its use is accelerating
climate
change.
16
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One Idea: GNext
17
A
n open innovation engine
designed to help companies
developing solutions for air,
water and bio
-
energy.
L
everages
Genencor’s
core
competencies in the discovery,
engineering, production and
supply of enzymes, proteins and
microorganisms
–
at large
-
scale
and a low price
-
point.
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Addressing society’s big needs
Improving air quality
•
Cleaning the Air
•
Preventing Pollution
18
Clean water for everyone
•
Potable, Industrial or
Agriculture Water
•
Pollution prevention or
remediation
Sustainable bio
-
energy
•
Affordable energy
•
Sustainable energy
•
Secure
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Who should partner with us
19
Two
Three
One
If you are developing
a solution for air,
water or bio
-
energy.
And require an
enzyme, protein or
microorganism as key
element of that
technology.
Talk with us.
Together we can accomplish what
can’t be don
e
alone. Thank you.
gnext.genencor.com
|
gnext@danisco.com
Copyright © 2012 DuPont or its affiliates. All rights reserved. The DuPont Oval Logo, DuPont™
Danisco
®
and all products denoted with ™ or
®
are
registered trademarks or trademarks of E. I. du Pont de Nemours and Company or its affiliates.
21
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Food
Health
Need to increase food supply
significantly
Rising raw material prices
Need for
affordable and
sustainable food
Trend for natural, clean label
product
Twin challenges of obesity
and aging
Chronic disease
Food safety and pandemics
Demand for healthy foods
We will be the premier specialty food ingredient and food safety leader
Nutrition
Safety
Sustainability
Nutrition & Health: Business Opportunity
22
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