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12 Δεκ 2012 (πριν από 4 χρόνια και 7 μήνες)

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Neural Stem Cells in
Treating Diseases of the
CNS

Brooke McCarthy

BME 281

Fall 2011

Stem Cells

Undifferentiated cells

Types

Cell division

Induced to become specialized cells

Physiologically

Experimentally

Neural Stem Cells

Most fundamental cell of the nervous system

Divides to create

Neurons

Astrocytes

Oligodendroglia

CNS

Malignant glioblastomas

Multiple sclerosis

Niemann
-
Pick’s disease

Current treatments

NSC Therapy

Inject

Migrate

Surround

Results

Multiple sclerosis

Niemann
-
Pick’s disease

Still too early


Pros

Best results

Injection

Either type of stem cell


Problems

Risks

BTSC

Mutation of NSC

Largest part of brain tumors

Resists treatments

Genetic engineering


Future

Genetic engineering

Cellular origins

Other diseases

Resources

Achanta, P. "Gliomagenesis and the Use of Neural

Stem Cells in



Brain Tumor Treatment."

Anticancer Agents Med Chem.
(2010):



121
-
30.

Pubmed
. Web. 17 Sept. 2011.

“Glioblastoma Multiforme.”
Medscape.

Web. 14 Sept. 2011. <http://

emedicine.medscape.com/article/283252
-
overview#showall>.

Taupin, P. "Potential of Neural Stem Cells for the Treatment of Brain



Tumors."

Clinical Medicine: Oncology.

(2008): 451
-
54.

PubMed
.



Web. 17 Sept. 2011.

“Stem Cell Information.”
The National Institutes of Health
. Web. 14


Sept. 2011. <http://stemcells.nih.gov/info/basics/basics1.asp>.

“What are Stem Cells?”
Medical News Today.

Web. 14 Sept. 2011.