CENTRAL TEXAS COLLEGE

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3/18/2013

CENTRAL TEXAS COLLEGE

SYLLABUS FOR BIOL 2421

MICROBIOLOGY

Semester Hours Credit: 4


INSTRUCTOR: Timothy Anderson, Ph.D.

OFFICE: NS10
13

PHONE: 526
-
1633

OFFICE HOURS:

EMAIL:
Timothy.Anderson@ctcd.edu



I.

INTRO
DUCTION


A
.

An introduction to microorganisms (microbes) and their relationships to humans,
the rest of the living world, and their non
-
living environment. Examination of the
fundamental principles of microbiology, to include the morphology , physiology,
genetics, and classification of microbes and their relationships to soil, food, water,
industry, disease, and immunology. Human pathogens are used as examples
wherever and whenever it is possible to do so.

B.

BIOL 2421 is designed for nursing and all heal
th
-
related majors. It is required for
p
re
-
medicine and nursing students. It is also a science elective for those seeking
the associate of science degree.

C.

This course is occupationally related and serves as preparation for careers in
medicine, nursing,

allied health, public health, and similar occupations.

D.

Prerequisite:

Because Microbiology is an
A
dvanced

Biology course

Biology
1406

is a
P
rerequisite

for taking BIOL 2421, as stated in the CTC Catalog
.
Successful completion of a Biology CLEP test can

be substituted for the Biology
1406 Pre
-
requisite but proof must be given to the instructor.


II.

COURSE
OUTCOMES


A
.

Instill an appreciation and understanding of microbiology as a science.

B
.

Teach the history of
microbiology

and its importance to evolution,

genetics,
medicine, and related fields.

C
.

Demonstrate proper microbial techniques and apply their use in various situations.

D
.

Develop critical thinking and analysis of data.

E
.

Provide background of microbiology and give students a knowledge base for
w
hich to draw on for critical thinking.

BIOL 2421


2

III.

INSTRUCTIONAL MATERIALS

A.

Required Text
(s)
:

Tortora, Funke, and Case. 200
9
. Microbiology: an Introduction.
10
th Edition.
Pearson/Benjamin Cummings

with Mastering Microbiology ISBN 0321694163,
or a 3 hole punch version
with Mastering Microbiology ISBN 032172240X, or
Mastering Microbiology alone if you buy your textbook used
. ISBN

0321681576
.

BUY Mastering Microbiology online for it is cheaper!

SEE BELOW


B.

Required Laboratory Manual:

Microbiology: Laboratory Theory and
App
lication. Brief Edition

2008
. Michael J. Leboffe and Burton E. Pierce. Morton
Publishing. ISBN:0895827050.


C.

Course

Microbiology Web site
:

You will find useful links, exam review
questions, a copy of the course syllabus and lecture schedule on this site.

Go

to
the CTC home page and click on “Faculty and Staff”, then on the drop down
menu which reads “Instructional Departments”, select Science & MLT and hit
“GO”
;

then click on “Faculty” and you will see my name, Dr. Timothy Anderson.
Click on my name and that

will take you to the Web site designed for this course.



D.

Access to Mastering Microbiology can be purchased from the Pearson
website:
http://www.masteringmicrobiology.com
. The course ID is
MMBANDERSON18
206. You must register using your FULL NAME.


E.

Tutoring:

Tutoring is available through Project Pass, Bldg. 106, Room 108. The
contact number is
254
-
526
-
1580
. This tutoring is free of charge but you must
register. Tutoring time slots fill up fast so if you t
hink you may
require

help I
suggest you sign up early before all of the available slots are filled.


IV.

COURSE REQUIREMENTS


Students are expected to put in
100%

effort to understand the concepts presented in
general microbiology. This effort will include re
ading the text in advance of lecture,
attendance in all classes, attentiveness and participation in class, maintenance of excellent
class notes and regular study. Details are provided below:

A.

You will be given a lecture schedule which details the readin
g

requirements.
Reading should always be done before the corresponding

lecture

to ensure
that you have the appropriate background to understand

the lecture material.

B.

You must take excellent notes during class. This means much more than

simply
copying
anything the instructor

writes on the board. You must

include enough in
your notes that you could repeat the lecture for someone else in your own words.

C.

Regular and punctual attendance is essential for success in this course.

Attendance
will be taken at

the beginning of each

lecture and laboratory session
. Students
arriving
LATE

to class are responsible for seeking out
the instructor

at the end of
the class session

and amending the attendance record
.
Failure to
have

the
attendance sheet

amended
, for any

reason, cons
ti
t
ut
es an absence.

Students
who exceed the maximum
2

permissible number of absences (as defined in the
BIOL 2421


3

CTC Catalog)
WILL BE

dismissed from the course with a grade of
“FN”
.
Lecture and laboratory sessions will begin promptly at the designate
d hour, and
students are required to be in the classroom or laboratory on time
.
Students who
are consistently tardy and/or absent will be counseled and further penalties will
result if the behavior continues.

D.

If you must be absent from any class meeti
ng, it is
YOUR

responsibility to

find
out what happened in class while you were gone. Make friends with

one or more
other students in class so that you can ask them what happened and secure any
assignments which were given during your absence. Absence on

a previous class
day is
NO

EXCUSE

for not having completed homework for the current class.
The policy governing missed exams and quizzes is detailed below in the
appropriate section.

E.

This course, like most other science courses, builds on itself and on

past

courses.
Concepts presented at the beginning of the course will recur, be

expanded on and
provide the foundation for later material. If you do

poorly on an exam, it is
important that you go back over the material to be

sure that you understand it.

If
you do not, it will likely come back to haunt you later in the course.

Your exam
will be available for review in the instructors


office for a period of 1 week
following the scheduled exam
week
.


F.

Office hours are posted on your instructor’s office d
oor. You are welcome

to
come by if you have any questions about anything in lecture, or if you

wish to ask
about something that interests you. If you do not understand

something, office
hours are the time and

the

place to be sure of getting help.

If the
office hours
conflict with your schedule, your instructor will make an appointment to meet
with you at a mutually convenient time.

G.

The following excerpt comes from your textbook and I think you will find it
invaluable. The pyramid of learning is as follow
s. We remember about:

10% of what we read

20% of what we hear

30% of what we see

50% of what we see and hear

70% of what we discuss with others

80% of what we experience personally

95% of what we teach to someone else


H.

There are NO planned
Extra credit pos
sibilities
.

V.

METHODS OF EVALUATION

A.



1

Mid term
Lab

Exam



1
00 points



1
Final Lab Exam



1
0
0 points



10 Case Studies




50 points

2

Lecture Exams (100 points each)

2
00 points



1 Comprehensive Final


2
00 points



1
Presentation




1
00

points



Maste
ring Microbiology


100 points



1 Dropped grade: see below


-
100 points

BIOL 2421


4

-------------








7
5
0 points possible



You may drop your lowest grade on lecture exam (I, II), Lab exam I or drop
a grade of “0” for a missed exam, (100 points). If you miss an exa
m for
ANY

reason there is NO dropping your lowest exam grade. All students must write
the Final lab exam and the Final comprehensive lecture exam. There are no
exceptions. All exams must be written in your registered class time
, failure to
do so will be co
unted as a missed exam or a grade of 0.

This applies to BOTH
lecture and lab exams.

You may write an exam prior to the regularly
scheduled class time with instructor approval.

To keep track of your current average in the course, make a chart for yourself
s
howing points possible and points earned. Divide the total points you have
earned by the total possible as of that date and find your percentage.

It is
YOUR

responsibility to record and keep track of your grades.



Assignment Name

Poin
ts

Possible

Points E
arned























Determination of Semester Grade:



Percentage

Points



Grade





90%
-
100%

6
75
-
7
5
0

points

A



80%
-
89%

600
-
6
74

points

B



70%
-
79%

525
-
5
9
9

points

C



60%
-
69%

450
-
524

points

D



0%
-
59%

0
-

4
49

points


F


B.

Make
-
up lecture

examinations and lab
examinations

WILL NOT

be given! If
you have a legitimate conflict with a regularly scheduled lecture exam time, you
must contact the instructor
at least 24 hours in advance

to arrange to take the
exam
early

but

not after the schedule
d

exam
.
Emergencies include any event that
causes you to miss the exam: car problems, car wrecks, sick children, being sick
yourself, oversleeping……….etc.


C.

All exams are announced in advance; a complete schedule is contained in the
course syllabus.

You
must write the exam during the lab or lecture time for which
you are officially registered. There are no exceptions.


BIOL 2421


5

Exams are primarily graded by Scantron machine

(100AS)
. Bring a Scantron
sheet to each exam.
If ever there is a discrepancy between an a
nswer in your
exam booklet and an answer on your Scantron sheet, the answer on your
Scantron sheet will be used.

D.

Bonus
2
2.5

points (
3
%
)

The instructor has the right to add from
0 to
3
%

to your final grade based on your
attendance, participation, and pre
paredness for both lecture and lab classes. This
is earned and is not a guarantee to anyone.


VI.

NOTES AND ADDITIONAL INSTRUCTIONS FROM THE INSTRUCTOR


A.

Instructor’s Office Hours:

Students are welcome to visit the instructor in his office
(NS 1031) during his

regularly scheduled office hours (listed in p. 1 of this
syllabus).

B.

Contacting the Instructor:

The instructor may be reached during his regularly
scheduled office hours a
t
254
-
526
-
1633. When the instructor is not in his office,
messages may be left wit
h the Science Department secretary or on the Science
Department answering machine a
t

254
-
25
6
-
1288.

C.

Unethical Behavior:

Cheating in any form will not be tolerated. Individuals
observed to be cheating on an examination will receive a grade of zero on that
particular examination. Giving information about an examination to someone
who has not yet taken the examination is considered a form a cheating. Likewise,
seeking information from an individual who has already taken the examination is
considered a form
of cheating. Individuals observed to be giving or seeking such
information will receive a grade of zero on that particular examination.

D.

Arriving Late to Take and Examination:

Students will have a maximum of one
hour and 20 minutes to take lecture exams (
t
wo

hours for the final exam) and one
hour and
20

minutes to take laboratory exams, starting with the time that the exam
booklets are passed out. Students arriving late to take an examination will not be

given any additional time to take the exam; they wil
l return their exam booklets at
the same time as students who arrived on time.

E.

Course Withdrawal:

It is the student’s responsibility to officially withdraw from a
course if circumstances prevent attendance. Any student who desires to, or mus
t
,
officially
withdraw from a course after the first scheduled class meeting must file
a Central Texas College Application for Withdrawal (CTC Form 59). The
withdrawal form must be signed by the student.


CTC Form 59 will be accepted at any time prior to Friday of the
12
th

week of
classes during the 16
-
week fall and spring semesters. The deadline for sessions of
other lengths is:



10
-
week sessions Friday of the 7
th

week


8


Week

sessions Friday of the 6
th

week


5
-

Week

sessions Friday of the 3
rd

week

The equivalent
date (75% of the semester) will be used for sessions of other
lengths. The specific last day to withdraw is published each semester in t
he
BIOL 2421


6

Schedule Bulletin.
A student who officially withdraws will be awarded the grade
of “W” provided the student’s attend
ance and academic performance are
satisfactory at the time of official withdrawal. Students must file a withdrawal
application with the College before they may be considered for withdrawal.

A student may not withdraw from a class for which the instructor
has previously
issued the student a grade of
“FN”

for nonattendance.

F
.

Administrative Withdrawal:

An administrative withdrawal may be initiated when
the student fails to meet College attendance requirements. The instructor will
assign the appropriate gra
de in CTC Form 59 for submission to the registrar.

G
.

Incomplete Grade:

The College catalog states, “An incomplete grade may be
given in those cases where the student has completed the majority of the
coursework but, because of personal illness, death in t
he immediate family, or
military orders, the student is unable to complete the requirements for a course.
…”Prior approval from the instructor is required before the grade of “I
P
” for
Incomplete is recorded. A student who merely fails to show for the fin
al
examination will receive a zero for the final and an “F” for the course.

H
.

Cellular Phones and Beepers
:

Cellular phones and beepers will be turned off
while the student is in the classroom or laboratory.

Text messaging during class
time is not permitte
d. If you choose do so your cell phone/hand held device will
become the property of the instructor.

If your cell phone rings

or buzzes

while
taking an exam consider your exam finished at that time and I will collect it
.

NO EXCEPTIONS
.

If there is a reaso
n why you should be contacted leave your
number with Student Life Services,
254
-
526
-
1258
, and they will come to notify
you.

Under
NO

circumstances should you ever leave the classroom to take a call.
If you do leave

the class

you will be marked absent for t
hat days


attendance
records

and not permitted to return
.

I
.

Americans
with

Disabilities Act (ADA):

Students requiring accommodations for
disabilities are responsible for notifying the instructor. Reasonable
accommodations will be granted in full complia
nce with federal and state law and
Central Texas College policy.

J
.

Instructor Discretion:

The instructor reserves the right of final decision in course
requirements.

K
.

Civility:

Individuals are expected to be cognizant of what a constructive
educational
experience is and respectful of those participation in a learning
environment. Failure to do so can result in
disciplinary

action up to and including
expulsion. Any type of student behavior that interferes with the rights of fellow
students will not be t
olerated, and students engaging in such behavior will be
asked to leave the classroom. Such behavior includes, but is not limited to, (1)
incessant chatting with a fellow student will other students are attempting to hear
BIOL 2421


7

the instructor, (2) popping bubbl
e gum, and (3) habitually asking irrelevant
questions.
Civility includes the following:



B
eing in class on time



Staying in class for the entire class period



L
e
aving class early only after informing your instructor


prior to class


of an unavoidable confl
ict requiring your early departure; if possible,
position yourself close to the door for minimum disruption of the class



Making sure your cellular phone is turned off, so that it does not ruing
during the class



Avoiding such uncivil conduct as talking, sle
eping, reading
papers/magazines, or working on some other class homework assignment



Using socially acceptable language in classroom discussions



Not making disparaging or degrading remarks about other students

L.

Letters of Reference:


Letters will be writt
en on a case by case basis.

M
.

Appointments:

If you have an appointment it must be scheduled outside class
time. Do not show up for a class and then ask to leave early. Most appointments
are known in advance and it is
YOUR

responsibility to adjust your sc
hedule
accordingly.

I
f

this is not possible you may still receive credit for the missed
lecture or lab by attending another scheduled section.

N.

Plagiarism Statement for Course


"Students agree that by taking this course, all required papers, exams, class

projects or other assignments submitted for credit may be submitted to
Turnitin.com or similar third parties to review and evaluate for originality and
intellectual integrity. A description of the services, terms and conditions of use,
and privacy policy
of Turnitin.com is available on its web site:
http://www.Turnitin.com


Students understand all work submitted to Turnitin.com will be added to its
database of papers. Students further understand that if the results
of such a review
support an allegation of academic dishonesty, the course work in question as well
as any supporting materials may be submitted to CTC official representatives for
investigation and possible initiation of disciplinary proceedings.



Plagia
rism: Statement and Definition

Though no definition can be wholly inclusive, the following definition sets the
boundaries on what is acceptable academic behavior while at CTC:

Plagiarism is an act in which a student uses someone else's words or ideas
witho
ut due acknowledgment in order to gain some form of reward.

Certain words and ideas in this simple
-
sounding definition need to be
clarified:

BIOL 2421


8

a.
"uses someone else's words"

is the unacknowledged use either of any
original or important words from another s
ource, or three or more consecutive
words from any unacknowledged source.

b.
"uses someone else's . . . ideas"
includes use without acknowledgment of any
interpretative idea, even a general idea taken from a general source, or any fact
not in general know
ledge. It also includes use of the paraphrased, altered,
condensed, or simplified phraseology from an unacknowledged source. It is
plagiarism when the unacknowledged use occurs in any written work, including
"homework" or practice work that will be graded
or is presumed to be the work of
the individual presenting it.

c.
"without due acknowledgment"
means any situation in which the instructor
cannot tell that the writer is not the primary source of the ideas and/or words.
Simply placing a work in a reference

or works cited list is not enough. Neither is
placing a parenthetical reference at the end of the paragraph. There is a clear need
for both the accuracy of quotations marks, appropriately placed parenthetical
references, and an accurate works cited page.
If any one of these is missing,
plagiarism could result.

d.
"someone else's"
includes, but is not limited to, any work that has been
published, including books, multi
-
volume works, academic journals, popular
magazines, or any papers/notes produced as "stud
y guides" or "study aids." It
includes all electronic sources. The phrase also includes the use of any
unpublished work, whether produced by a fellow student or not, whether
borrowed, stolen, or paid for (including work from internet paper services). It
do
es not include broad general knowledge or lecture information given in the
class for which the paper is written. The writer must check with the instructor to
determine if the use of class/lecture notes is an acceptable source of information.

The phrase a
lso includes excessive aid accepted from, or given to, other students,
even in spoken form. Excessive aid, for instance, includes ideas dictated to a
student and placed in the student's paper.

e.
"reward"

means benefit, tangible or intangible, received by

any party
involved in the acts of plagiarism or cheating.


Ignorance of the precise definition of plagiarism is no more an excuse than
ignorance of the law is an excuse. It is up to the student to become aware of
the general principles and the specific cr
iteria of individual instructors.


Cheating: Statement and Definition


Cheating is more often than not more clear an offense than is plagiarism. Cheating
is an act of
:

a. giving, receiving, and/or aiding in either the giving or receiving of any
unauthorize
d information during

a

test

This includes
cell phones, IPads, Kindle,
etc
.

b. communicating the contents, general or specific, of any test of quiz to include
the lending or borrowing of past tests or quizzes when the instructor has not
specifically sanctio
ned this act,

BIOL 2421


9

c. using in the testing area any covert and unacceptable means of receiving or
giving information, and



d. taking a test/quiz for another student.

Beyond tests and quizzes, if a student turns in one paper for two classes without
gaining cons
ent from both instructors, it is considered an act of dishonesty and,
therefore, an act of cheating (i.e., receiving double credit for a single assignment).

Any time a student is in doubt about what he or she is going to do, it is the
student's responsibil
ity to check with the instructor before doing it. Also,
when you submit a paper there is the possibility that it may in turn be
submitted to turnitin.com or other plagiarism detection sources. Such
sources may allow free access to your paper by other int
ernet users.

The CTC catalog is very clear regarding the consequences of plagiarism or
cheating: “Students guilty of scholastic dishonesty will be administratively
dropped from the course with a grade of ‘F’ and subject to disciplinary
action, which may in
clude suspension and expulsion.”



VII.

COURSE COMPETENCIES (BROAD OBJECTIVES)

At the completion of this course, students should be able to:

1.

Define microbiology and state its importance to evolution, genetics, medicine,
and related fields.

2.

Define and

give examples of: Sporadic, Endemic, Epidemic, and Pandemic
diseases.

3.

Draw 10 bacterial structures and name their function.

4.

Define antigenic s
hift and antigenic drift. Give

examples of each.

5.

List and describe the Scientific Method.

6.

Who and why

was Robert Koch important in the study of microbiology.

7.

Discuss in detail how bacterial cell wall structure and how cell wall composition
affect Gram staining and antibiotic action.

8.

List and describe Koch’s postulates.

9.

What is the normal microbi
al
flora?

List 5 examples each of Gram
-
negative and
Gram
-
positive bacteria.

10.

What is the importance of antibiotic resistance and how does it develop?

11.

What is a microbial pathogen and what makes it pathogenic?

12.

List 5 host defense mechanisms again
st infection.

13.

Describe transcription and translation in both prokaryotes and eukaryotes and
explain the role of each in protein synthesis.

14.

Describe 4 methods of sterilization.

15.

Describe the genetic code as it relates to DNA structure and protein

synthesis.

16.

Name three differences between DNA and RNA.

17.

What is a food
-
borne pathogen? Give 3 examples of the disease that each causes.

18.

How are bacteria isolated, cultivated, and stored?

19.

Demonstrate the aseptic technique.

20.

Use observatio
ns to form hypotheses and design experiments to test hypotheses.

21.

After completion of microbiology labs, use knowledge of subject with critical
analysis to analyze

the results of each.

22.

What are plasmids, phage, and transposons? Why are they importan
t?

BIOL 2421


10

23.

Describe epidemiology and state its importance.

24.

Identify common microorganisms with a microscope. Use oil immersion when
necessary.

25.

Demonstrate the proper use and care of the microscope and name the function of
all parts of the microscope.

2
6.

What is a vaccine? List 4 types, how they are made, and the diseases they prevent.

27.

Compare and contrast anaerobic and aerobic respiration.

28.

What is an emerging pathogen and give examples?

29.

Identify an unknown bacterial sample.

30.

Determine ba
cterial counts.




VI
II
.

COURSE OUTLINE AND LEARNING OBJECTIVES

1: The Microbial World and You

Learning Objectives


1.

List several ways in which microbes affect our lives.


2.

Recognize the system of scientific nomenclature that uses two names: a genus
and specific epithet.


3.

Differentiate among the major characteristics of each group of microorganisms.


4.

List the three domains.


5.

Explain the importance of observations made by Hooke and van Leeuwenhoek.


6.

Compare spontaneous generation and bi
ogenesis.


7.

Identify the contributions to microbiology made by Needham, Spallanzani, Virchow, and Pasteur.


8.

Identify the importance of Koch’s postulates.


9.

Explain how Pasteur’s work influenced Lister and Koch.

10.

Identify the importance of Je
nner’s work.

11.

Identify the contributions to microbiology made by Ehrlich and Fleming.

12.

Define bacteriology, mycology, parasitology, immunology, and virology.

13.

Explain the importance of recombinant DNA technology.

14

List at least four bene
ficial activities of microorganisms.

15.

List two examples of biotechnology that use recombined DNA technology and two examples that do not.

16.

Define normal microbiota and resistance.

17.

Define and describe several infectious diseases.

18.

Defin
e emerging infectious disease.


2: Chemical Principles

LEARNING OBJECTIVES


1.

Describe the structure of an atom and its relation to the chemical properties of elements.


2.

Define ionic bond, covalent bond, hydrogen bond, molecular weights, and mole.


3.

Diagram three basic types of chemical reactions.


4.

List several properties of water that are important to living systems.


5.

Define acid, base, salt, and pH.


6.

Distinguish between organic and inorganic compounds.


7.

Define functional group.


8.

Ident
ify the building blocks of carbohydrates.


9.

Differentiate between simple lipids, complex lipids, and steroids.

10.

Identify the building blocks and structure of proteins.

11.

Identify the building blocks of nucleic acids.

12.

Describe the role of ATP
in cellular activities.


3: Observing Microorganisms Through a Microscope

LEARNING OBJECTIVES

BIOL 2421


11


1.

List the metric units of measurement, including their metric equivalents that are used for microorganisms.


2.

Diagram the path of light through a compound mi
croscope.


3.

Define total magnification and resolution.


4.

Identify a use for darkfield, phase
-
contrast, differential interference contrast, fluorescence, confocal, and



s
canning acoustic microscopy, and compare each with brightfield illumination.


5.

Explain how electron microscopy differs from light microscopy.


6.

Identify one use for the TEM, SEM, and scanned
-
probe microscopes.


7.

Differentiate between an acidic dye and a basic dye.


8.

Compare simple, differential, and special stains.


9.

List the

steps in preparing a Gram stain, and describe the appearance of gram
-
positive and gram
-
negative cells



after each step.

10.

Compare and contrast the Gram stain and the acid
-
fast stain.

11.

Explain why each of the following is used: capsule stain, endo
spore stain, flagella stain.


4: FUNCTIONAL ANATOM
Y OF PROKARYOTIC AND

EUKARYOTIC CELLS

LEARNING OBJECTIVES


1.

Compare and contrast the overall cell structure of prokaryotes and eukaryotes.


2.

Identify the three basic shapes of bacteria.


3.

Describe the

structure and function of the glycocalyx, flagella, axial filaments, fimbriae, and pili.


4.

Compare and contrast the cell walls of gram
-
positive bacteria, gram
-
negative bacteria, acid
-
fast bacteria,



archaea, and mycoplasmas.


5.

Differentiate between
protoplast, spheroplast, and L form.


6.

Describe the structure, chemistry, and functions of the prokaryotic plasma membrane.


7.

Define simple diffusion, facilitated diffusion, osmosis, active transport, and group translocation.


8.

Identify the functions

of the nuclear area, ribosomes, and inclusions.


9.

Describe the functions of endospores, sporulation, and endospore germination.

10.

Differentiate between prokaryotic and eukaryotic flagella.

11.

Compare and contrast prokaryotic and eukaryotic cell walls

and glycocalyxes.

12.

Compare and contrast prokaryotic and eukaryotic plasma membranes.

13.

Compare and contrast prokaryotic and eukaryotic cytoplasms.

14.

Define organelle.

15.

Describe the functions of the nucleus, endoplasmic reticulum, ribosomes, Golg
i complex, lysosomes, vacuoles,



mitochondria, chloroplasts, peroxisomes, and centrosomes.

16.

Discuss evidence that supports the endosymbiotic theory of eukaryotic evolution.


5: Microbial Metabolism

LEARNING OBJECTIVES


1.

Define metabolism, and descri
be the fundamental differences between anabolism and catabolism.


2.

Identify the role of ATP as an intermediate between catabolism and anabolism.


3.

Identify the components of an enzyme.


4.

Describe the mechanism of enzymatic action.


5.

List the factor
s that influence enzymatic activity.


6.

Define ribozyme.


7.

Explain what is meant by oxidation

reduction.


8.

List and provide examples of three types of phosphorylation reactions that generate ATP.


9.

Explain the overall function of biochemical pathway
s.

10.

Describe the chemical reactions of glycolysis.

11.

Explain the products of the Krebs cycle.

12.

Describe the chemiosmotic model for ATP generation.

13.

Compare and contrast aerobic and anaerobic respiration.

14.

Describe the chemical reactions of, a
nd list some products of, fermentation.

15.

Describe how lipids and proteins undergo catabolism.

16.

Provide two examples of the use of biochemical tests to identify bacteria.

17.

Compare and contrast cyclic and noncyclic photophosphorylation.

18.

Compare
and contrast the light
-
dependent and light
-
independent reactions of photosynthesis.

19.

Compare and contrast oxidative phosphorylation and photophosphorylation.

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12

20.

Write a sentence to summarize energy production in cells.

21.

Categorize the various nutrit
ional patterns among organisms according to carbon source and mechanisms of



carbohydrate catabolism and ATP generation.

22.

Describe the major types of anabolism and their relationship to catabolism.

23.

Define amphibolic pathways.


6: Microbial Growth

L E A R N I N G O B J E C T I V E S


1. Classify microbes into five groups on the basis of preferred temperature range.


2. Identify how and why the pH of culture media is controlled.


3. Explain the importance of osmotic pressure to microbial growth.


4. Provide a use fo
r each of the four elements (carbon, nitrogen, sulfur, and phosphorus) needed in large amounts
for microbial growth.


5. Explain how microbes are classified on the basis of oxygen requirements.


6. Identify ways in which aerobes avoid damage by toxic forms

of oxygen.


7. Distinguish between chemically defined and complex media.


8. Justify the use of each of the following: anaerobic techniques, living host cells, candle jars, selective and
differential media, enrichment media.


9. Define colony.

10. Describ
e how pure cultures can be isolated by using streak plates.

11. Explain how microbes are preserved by deep
-
freezing and lyophilization (freeze
-
drying).

12. Define bacterial growth, including binary fission.

13. Compare the phases of microbial growth and de
scribe their relation to generation time.

14. Explain four direct methods of measuring cell growth.

15. Differentiate between direct and indirect methods of measuring cell growth.

16. Explain three indirect methods of measuring cell growth.



7: The Contro
l of Microbial Growth

LEARNING OBJECTIVES


1.

Define the following key terms related to microbial control: sterilization, disinfection, antisepsis, degerming,



sanitization, biocide, germicide, bacteriostasis, and asepsis.


2.

Describe the patterns of mi
crobial death caused by treatments with microbial control agents.


3.

Describe the effects of microbial control agents on cellular structures.


4.

Compare the effectiveness of moist heat (boiling, autoclaving, pasteurization) and dry heat.


5.

Describe how

filtration, low temperature, high pressure, desiccation, and osmotic pressure suppress microbial



growth.


6.

Explain how radiation kills cells.


7.

List the factors related to effective disinfection.


8.

Interpret results of use
-
dilution tests and the
disk
-
diffusion method.


9.

Identify the methods of action and preferred uses of chemical disinfectants.

10.

Differentiate between halogens used as antiseptics and as disinfectants.

11.

Identify the appropriate uses for surface
-
active agents.

12.

List the a
dvantages of glutaraldehyde over other chemical disinfectants.

13.

Identify the method of sterilizing plastic labware.

14.

Explain how microbial control is affected by the type of microbe.


8: Microbial Genetics

LEARNING OBJECTIVES


1.

Define genetics, gen
ome, chromosome, gene, genetic code, genotype, phenotype, and genomics.


2.

Describe how DNA serves as genetic information.


3.

Describe the process of DNA replication.


4.

Describe protein synthesis, including transcription, RNA processing, and translatio
n.


5.

Explain the regulation of gene expression in bacteria by induction, repression, and catabolite repression.


6.

Classify mutations by type, and describe how mutations are prevented and repaired.


7.

Define mutagen.


8.

Describe two ways mutations can

be repaired.

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13


9.

Describe the effect of mutagens on the mutation rate.

10.

Outline methods of direct and indirect selection of mutants.

11.

Identify the purpose and outline the procedure for the Ames test.

12.

Compare the mechanisms of genetic recombinati
on in bacteria.

13.

Differentiate between horizontal and vertical gene transfer.

14.

Describe the functions of plasmids and transposons.

15.

Discuss how genetic mutation and recombination provide material for natural selection to act on.


9: Biotechnology
and Recombinant DNA

LEARNING OBJECTIVES


1.

Compare and contrast biotechnology, genetic modification, and recombinant DNA.


2.

Identify the roles of a clone and a vector in making recombined DNA.


3.

Compare selection and mutation.


4.

Define restriction e
nzymes, and outline how they are used to make recombinant DNA.


5.

List the four properties of vectors.


6.

Describe the use of plasmid and viral vectors.


7.

Outline the steps in PCR and provide an example of its use.


8.

Describe five ways of getting DNA

into a cell.


9.

Describe how a gene library is made.

10.

Differentiate cDNA from synthetic DNA.

11.

Explain how each of the following are used to locate a clone: antibiotic
-
resistance genes, DNA probes, gene



products.

12.

List one advantage of enginee
ring the following:
E. coli, Saccharomyces cerevisiae,

mammalian cells, plant



cells.

13.

List at least five applications of rDNA Technology.

14.

Define RNAi.

15.

Discuss the value of the Human Genome Project.

16.

Define the following terms: random shotg
un sequencing, bioinformatics, proteomics.

17.

Diagram the Southern blot procedure and provide an example of its use.

18.

Diagram DNA fingerprinting and provide an example of its use.

19.

Outline genetic engineering with
Agrobacterium.

20.

List the advanta
ges of, and problems associated with, the use of genetic modification techniques.

10: Classification of Microorganisms

LEARNING OBJECTIVES


1.

Define taxonomy, taxon, and phylogeny.


2.

Discuss the limitations of a two
-
kingdom classification system.


3.

Id
entify the contributions of Linnaeus, von Nägali, Chatton, Whittaker, and Woese.


4.

Discuss the advantages of the three
-
domain system.


5.

List the characteristics of the Bacteria, Archaea, and Eukarya domains.


6.

Differentiate among eukaryotic, prokaryo
tic, and viral species.


7.

Explain why scientific names are used.


8.

List the major taxa.


9.

Differentiate between culture, clone, and strain.

10.

List the major characteristics used to differentiate the three kingdoms of multicellular Eukarya.

11.

Defi
ne protist.

12.

Compare and contrast classification and identification.

13.

Explain the purpose of
Bergey’s Manual.

14.

Describe how staining and biochemical tests are used to identify bacteria.

15.

Differentiate Western blotting and Southern blotting.

16.

Explain how serological tests and phage typing can be used to identify an unknown bacterium.

17.

Describe how a newly discovered microbe can be classified by: DNA base composition, DNA fingerprinting,



and PCR.

18.

Describe how microorganisms can be ide
ntified by nucleic acid hybridization, Southern blotting, DNA chips,
ribotyping, and FISH.

19.

Differentiate a dichotomous key from a cladogram.


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14

11: The Prokaryotes: Domains Bacteria and Archaea

LEARNING OBJECTIVES


1.

The Learning Objectives in this chap
ter will help you become familiar with these organisms and to look for

similarities and differences between organisms. You will draw a dichotomous key to differentiate the bacteria

described in each group.


2.

Make a dichotomous key to distinguish among
the alphaproteobacteria described in this chapter.


3.

Make a dichotomous key to distinguish among the betaproteobacteria described in this chapter.


4.

Make a dichotomous key to distinguish among the orders of gammaproteobacteria described in this chapter
.


5.

Make a dichotomous key to distinguish among the deltaproteobacteria described in this chapter.


6.

Make a dichotomous key to distinguish among the epsilonproteobacteria described in this chapter.


7.

Make a dichotomous key to distinguish among the gr
am
-
negative nonproteobacteria described in this chapter.


8.

Compare and contrast the green and purple photosynthetic bacteria with the cyanobacteria.


9.

Make a dichotomous key to distinguish among the low G + C gram
-
positive bacteria described in this ch
apter.

10.

Make a dichotomous key to distinguish among the high G 1 C gram
-
positive bacteria described in this chapter.

11.

Make a dichotomous key to distinguish Chlamydias, spirochetes,
Cytophaga,

Bacteroidetes, and Fusobacteria.


12: The Eukaryotes: Fung
i, Algae, Protozoa, and Helminths

Learning Objectives


1.

List the defining characteristics of fungi.


2.

Differentiate between sexual and asexual reproduction, and describe each of these processes in fungi.


3.

List the defining characteristics of the thr
ee phyla of fungi described in this chapter.


4.

Identify two beneficial and two harmful effects of fungi.


5.

List the distinguishing characteristics of lichens, and describe their nutritional needs.


6.

Describe the roles of the fungus and the alga in a
lichen.


7.

List the defining characteristics of algae.


8.

List the outstanding characteristics of the five phyla of algae discussed in this chapter.


9.

List the defining characteristics of protozoa.

10.

Describe the outstanding characteristics of the se
ven phyla of protozoa discussed in this chapter, and give an

example of each.

11.

Differentiate an intermediate host from a definitive host.

12.

Compare and contrast cellular slime molds and plasmodial slime molds.

13.

List the distinguishing characterist
ics of parasitic helminths.

14.

Provide a rationale for the elaborate life cycles of parasitic worms.

15.

List the characteristics of the two classes of parasitic helminths, and give an example of each.

16.

List the characteristics of parasitic nematodes,
and give an example of infective eggs and infective larvae.

17.

Compare and contrast platyhelminthes and nematodes.

18.

Define arthropod vector.

19.

Differentiate between a tick and a mosquito, and name a disease transmitted by each.


13: Viruses, Viroids,

and Prions

Learning Objectives


1.

Differentiate a virus from a bacterium.


2.

Describe the chemical composition and physical structure of an enveloped and a nonenveloped virus.


3.

Define viral species.


4.

Give an example of a family, genus, and common
name for a virus.


5.

Describe how bacteriophages are cultured.


6.

Describe how animal viruses are cultured.


7.

List three techniques that are used to identify viruses.


8.

Describe the lytic cycle of T
-
even bacteriophages.


9.

Describe the lysogenic cyc
le of bacteriophage lambda.

10.

Compare and contrast the multiplication cycle of DNA
-

and RNA
-
containing animal viruses.

11.

Define oncogene and transformed cell.

12.

Discuss the relationship between DNA
-

and RNA
-
containing viruses and cancer.

13.

Provide
an example of a latent viral infection.

14.

Differentiate between persistent viral infections and latent viral infections.

15.

Discuss how a protein can be infectious.

BIOL 2421


15

16.

Differentiate virus, viroid, and prion.

17.

Name a virus that causes a plant disease
.


14: Principles of Disease and Epidemiology

Learning Objectives


1.

Define pathology, etiology, infection, and disease.


2.

Define normal and transient microbiota.


3.

Compare commensalism, mutualism, and parasitism, and give an example of each.


4.

Cont
rast normal and transient with opportunistic microbes.


5.

List Koch’s postulates.


6.

Differentiate a communicable from a noncommunicable disease.


7.

Categorize diseases according to frequency of occurrence.


8.

Categorize diseases according to severity.


9.

Define herd immunity.

10.

Identify four predisposing factors for disease.

11.

Put the following terms in proper sequence in terms of the pattern of disease: period of decline, period of

convalescence, period of illness, prodromal period, incubation p
eriod.

12.

Define reservoir of infection.

13.

Contrast human, animal, and nonliving reservoirs, and give one example of each.

14.

Explain three methods of disease transmission.

15.

Define nosocomial infections and explain their importance.

16.

Define comp
romised host.

17.

List several methods of disease transmission in hospitals.

18.

Explain how nosocomial infections can be prevented.

19.

List several probable reasons for emerging infectious diseases, and name one example for each reason.

20.

Define epidem
iology and describe three types of epidemiologic investigation.

21.

Identify the function of the CDC.

22.

Define the following terms: morbidity, mortality, and notifiable disease.


15: Microbial Mechanisms of Pathogenicity

Learning Objectives


1.

Identify

the principal portals of entry.


2.

Define LD
50

and ID
50
.


3.

Using examples, explain how microbes adhere to host cells.


4.

Explain how capsules and cell wall components contribute to pathogenicity.


5.

Compare the effects of coagulases, kinases, hyaluro
nidase, and collagenase.


6.

Define and give an example of antigenic variation.


7.

Describe how bacteria use the host cell’s cytoplasm to enter the cell.


8.

Describe the function of siderophores.


9.

Provide an example of direct damage, and compare this
to toxin production.

10.

Contrast the nature and effects of exotoxins and endotoxins.

11.

Outline the mechanisms of action of A
-
B toxins, membrane
-
disrupting toxins, and superantigens. Classify



diphtheria toxin, erythrogenic toxin, botulinum toxin, teta
nus toxin,
Vibrio

enterotoxin, and staphylococcal



enterotoxin.

12.

Identify the importance of the LAL assay.

13.

Using examples, describe the role of plasmids and lysogeny in pathogenicity.

14.

List nine cytopathic effects of viral infections.

15.

Discu
ss the causes of symptoms in fungal, protozoan, helminthic, and algal diseases.

16.

Compare and contrast portal of entry and portal of exit.


16: Innate Immunity: Nonspecific Defenses of the Host

Learning Objectives


1.

Differentiate between innate and ada
ptive immunity.


2.

Define toll
-
like receptors.


3.

Describe the role of the skin and mucous membranes in innate immunity.


4.

Differentiate physical from chemical factors, and list five examples of each.

BIOL 2421


16


5.

Describe the role of normal microbiota in innat
e resistance.


6.

Classify phagocytic cells, and describe the roles of granulocytes and monocytes.


7.

Define differential white blood cell count.


8.

Define phagocyte and phagocytosis.


9.

Describe the process of phagocytosis, and include the stages of ad
herence and ingestion.

10.

Identify six methods of avoiding destruction by phagocytes.

11.

List the stages of inflammation.

12.

Describe the roles of vasodilation, kinins, prostaglandins, and leukotrienes in inflammation.

13.

Describe phagocyte migration.

14.

Describe the cause and effects of fever.

15.

List the components of the complement system.

16.

Describe three pathways of activating complement.

17.

Describe three consequences of complement activation.

18.

Define interferons.

19.

Compare and contrast
the actions of a
-
IFN and b
-
IFN with g
-
IFN.

20.

Describe the role of transferrins in innate immunity.

21.

Describe the role of antimicrobial peptides in innate immunity.


17: Adaptive Immunity: Specific Defenses of the Host

Learning Objectives


1.

Different
iate between innate and adaptive immunity.


2.

Differentiate between humoral and cellular immunity.


3.

Define antigen, epitope, and hapten.


4.

Explain the function of antibodies and describe their structural and chemical characteristics.


5.

Name one fun
ction for each of the five classes of antibodies.


6.

Compare and contrast T
-
dependent antigens and T
-
independent antigens.


7.

Differentiate between plasma cell and memory cell.


8.

Describe clonal selection.


9.

Describe how a human can produce different

antibodies.

10.

Describe four outcomes of an antigen
-
antibody reaction.

11.

Describe at least one function of each of the following: M cells, T
H
1 cells, T
H
2 cells, T
C

cells, T
g

cells, CTL,

NK cell.

12.

Differentiate between helper T, cytotoxic T, and reg
ulatory T cells.

13.

Differentiate between T
H
1 and T
H
2 cells.

14.

Define apoptosis.

15.

Define antigen
-
presenting cell.

16.

Describe the function of natural killer cells.

17.

Describe the role of antibodies and natural killer cells in antibody
-
dependent ce
ll
-
mediated cytotoxicity.

18.

Identify at least one function of each of the following: cytokines, interleukins, interferons.

19.

Distinguish a primary from a secondary immune response.

20.

Contrast the four types of adaptive immunity.


18: Practical Applic
ations of Immunology

Learning Objectives


1.

Define vaccine.


2.

Explain why vaccination works.


3.

Differentiate between the following, and provide an example of each: attenuated, inactivated, toxoid, subunit,

and conjugated vaccines.


4.

Contrast subuni
t vaccines and nucleic acid vaccines.


5.

Compare and contrast the production of whole
-
agent vaccines, recombinant vaccines, and DNA vaccines.


6.

Define adjuvant.


7.

Explain the value of vaccines, and discuss acceptable risks for vaccines.


8.

Explain ho
w antibodies are used to diagnose diseases.


9.

Define monoclonal antibodies, and identify their advantage over conventional antibody production.

10.

Explain how precipitation and immunodiffusion tests work.

BIOL 2421


17

11.

Differentiate direct from indirect agglutina
tion tests.

12.

Differentiate agglutination from precipitation tests.

13.

Define hemagglutination.

14.

Explain how a neutralization test works.

15.

Differentiate precipitation from neutralization tests.

16.

Explain the basis for the complement
-
fixation tes
t.

17.

Compare and contrast direct and indirect fluorescent
-
antibody tests.

18.

Explain how direct and indirect ELISA tests work.

19.

Explain the importance of monoclonal antibodies.


19: Disorders Associated with the Immune System

Learning Objectives


1.

Define hypersensitivity.


2.

Describe the mechanism of anaphylaxis.


3.

Compare and contrast systemic and localized anaphylaxis.


4.

Explain how allergy skin tests work.


5.

Define desensitization and blocking antibody.


6.

Describe the mechanism of cytoto
xic reactions and how drugs can induce them.


7.

Describe the basis of the ABO and Rh blood group systems.


8.

Explain the relationship between blood groups and blood transfusions and hemolytic disease of the newborn.


9.

Describe the mechanism of immune c
omplex reactions.

10.

Describe the mechanism of cell
-
mediated reactions, and name two examples.

11.

Describe a mechanism for self
-
tolerance.

12.

Give an example of immune complex, cytotoxic, and cell
-
mediated autoimmune diseases.

13.

Define HLA complex, an
d explain its importance in disease susceptibility and tissue transplants.

14.

Explain how the rejection of a transplant occurs.

15.

Define privileged site.

16.

Define autograft, isograft, allograft, and xenotransplant.

17.

Explain how graft
-
versus
-
host di
sease occurs.

18.

Explain how rejection of a transplant is prevented.

19.

Describe the immune responses to cancer and how cancer cells evade immune responses.

20.

Give two examples of immunotherapy.

21.

Compare and contrast congenital and acquired immune d
eficiencies.

22.

Give two examples of how emerging infectious diseases arise.

23.

Explain the attachment of HIV to a host cell.

24.

List two ways in which HIV avoids the host’s antibodies.

25.

Describe the stages of HIV infection.

26.

Describe the effects
of HIV infection on the immune system.

27.

Describe how HIV infection is diagnosed.

28.

List the routes of HIV transmission.

29.

Identify geographic patterns of HIV transmission.

30.

List the current methods of preventing and treating HIV infection.


20: A
ntimicrobial Drugs

Learning Objectives


1.

Identify the contributions of Paul Ehrlich and Alexander Fleeting to chemotherapy.


2.

Name the microbes that produce most antibiotics.


3.

Describe the problems of chemotherapy for viral, fungal, protozoan, and h
elminthic infections.


4.

Define the following terms: spectrum of activity, broad
-
spectrum drugs, superinfection.


5.

Identify five modes of action of antimicrobial drugs.


6.

Explain why the drugs described in this section are specific for bacteria.


7.

L
ist the advantages of each of the following over penicillin: semisynthetic penicillins, cephalosporins, and

vancomycin.


8.

Explain why INH and ethambutol are antimycobacterial agents.


9.

Describe how each of the following inhibits protein synthesis: ami
noglycosides, tetracyclines, chloramphenicol,

macrolides.

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18

10.

Compare the mode of action of polymyxin B, bacitracin, and neomycin.

11.

Describe how rifamycins and quinolones kill bacteria.

12.

Describe how sulfa drugs inhibit microbial growth.

13.

Explain

the modes of action of currently used antifungal drugs.

14.

Explain the modes of action of currently used antiviral drugs.

15.

Explain the modes of action of currently used antiprotozoan and antihelminthic drugs.

16.

Describe two tests for microbial susce
ptibility to chemotherapeutic agents.

17.

Describe the mechanisms of drug resistance.

18.

Compare and contrast synergism and antagonism.

19.

Identify three areas of research on new chemotherapeutic agents.


21: Microbial Diseases of the Skin and Eyes

Learn
ing Objectives


1.

Describe the structure of the skin and mucous membranes and the ways pathogens can invade the skin.


2.

Provide examples of normal skin microbiota, and state their locations and ecological roles of its members.


3.

Differentiate staphylo
cocci from streptococci, and name several skin infections caused by each.


4.

List the causative agent, method of transmission, and clinical symptoms of
Pseudomonas
, dermatitis, otitis

externa, acne.


5.

List the causative agent, method of transmission, a
nd clinical symptoms of these skin infections: warts,

smallpox, chickenpox, shingles, cold sores, measles, rubella, fifth disease, roseola.


6.

Differentiate cutaneous from subcutaneous mycoses, and provide an example of each.


7.

List the causative agent

of and predisposing factors for candidiasis.


8.

List the causative agent, method of transmission, clinical symptoms, and treatment for scabies and pediculosis.


9.

Define conjunctivitis.

10.

List the causative agent, method of transmission, and clinical
symptoms of these eye infections: neonatal

gonorrheal ophthalmia, inclusion conjunctivitis, trachoma.

11.

List the causative agent, method of transmission, and clinical symptoms of these eye infections: herpetic

keratitis,
Acanthamoeba

keratitis.


22: Mi
crobial Diseases of the Nervous System

Learning Objectives


1.

Define central nervous system and blood
-
brain barrier.


2.

Differentiate meningitis from encephalitis.


3.

Discuss the epidemiology of meningitis caused by
H. influenzae
,

S. pneumoniae
,

N. meni
ngitidis
, and
L.

monocytogenes
.


4.

Explain how bacterial meningitis is diagnosed and treated.


5.

Discuss the epidemiology of tetanus, including mode of transmission, etiology, disease symptoms, and

preventive measures.


6.

State the causative agent, sy
mptoms, suspect foods, and treatment for botulism.


7.

Discuss the epidemiology of leprosy, including mode of transmission, etiology, disease symptoms, and

preventive measures.


8.

Discuss the epidemiology of poliomyelitis, rabies, and arboviral encephali
tis, including mode of transmission,

etiology, and disease symptoms.


9.

Compare the Salk and Sabin vaccines.

10.

Compare preexposure and postexposure treatments for rabies.

11.

Explain how arboviral encephalitis can be prevented.

12.

Identify the causati
ve agent, reservoir, symptoms, and treatment for cryptococcosis.

13.

Identify the causative agent, vector, symptoms, and treatment for African trypanosomiasis and amebic

meningoencephalitis.

14.

List the characteristics of diseases caused by prions.

15.

L
ist some possible causes of chronic fatigue syndrome.


23: Microbial Diseases of the Cardiovascular and Lymphatic Systems

Learning Objectives


1.

Identify the role of the cardiovascular and lymphatic systems in spreading and eliminating infections.


2.

Lis
t the signs and symptoms of septicemia, and explain the importance of infections that develop into
BIOL 2421


19


septicemia.


3.

Differentiate gram
-
negative sepsis, gram
-
positive sepsis, and puerperal sepsis.


4.

Describe the epidemiologies of bacterial endocarditis an
d rheumatic fever.


5.

Discuss the epidemiology of tularemia.


6.

Discuss the epidemiology of brucellosis.


7.

Discuss the epidemiology of anthrax.


8.

Discuss the epidemiology of gas gangrene.


9.

List three pathogens that are transmitted by animal bites
and scratches.

10.

Compare and contrast the causative agents, vectors, reservoirs, symptoms, treatments, and preventive measures

for plague, Lyme disease, and Rocky Mountain Spotted Fever.

11.

Identify the vector, etiology, and symptoms of five diseases t
ransmitted by ticks.

12.

Describe the epidemiologies of epidemic typhus, endemic murine typhus, and spotted fevers.

13.

Describe the epidemiologies of CMV inclusion disease, Burkitt’s lymphoma, and infectious mononucleosis.

14.

Compare and contrast the cau
sative agents, vectors, reservoirs, and symptoms for yellow fever, dengue, and

dengue hemorrhagic fever.

15.

Compare and contrast the causative agents, modes of transmission, reservoirs, and symptoms for Ebola

hemorrhagic fever and
Hantavirus

pulmonary s
yndrome.

16.

Compare and contrast the causative agents, modes of transmission, reservoirs, symptoms, and treatments for

Chagas’ disease, toxoplasmosis, malaria, leishmaniasis, and babesiosis.

17.

Discuss the worldwide effects of these diseases on human he
alth.

18.

Diagram the life cycle of
Schistosoma,

and show where the cycle can be interrupted to prevent human


24: Microbial Diseases of the Respiratory System

Learning Objectives


1.

Describe how microorganisms are prevented from entering the respirator
y system.


2.

Characterize the normal microbiota of the upper and lower respiratory systems.


3.

Differentiate among pharyngitis, laryngitis, tonsillitis, sinusitis, and epiglottitis.


4.

List the causative agent, symptoms, prevention, preferred treatment,

and laboratory identification tests for



streptococcal pharyngitis, scarlet fever, diphtheria, cutaneous diphtheria, and otitis media.


5.

List the causative agents and treatments for the common cold.


6.

List the causative agent, symptoms, prevention,
preferred treatment, and laboratory identification tests for



pertussis and tuberculosis.


7.

Compare and contrast the seven bacterial pneumonias discussed in this chapter.


8.

List the etiology, method of transmission, and symptoms of melioidosis.


9.

L
ist the causative agent, symptoms, prevention, and preferred treatment for viral pneumonia, RSV, and



influenza.

10.

List the causative agent, mode of transmission, preferred treatment, and laboratory identification tests for four



fungal diseases of t
he respiratory system.


BIOL 2421


20


Lecture Schedule

(
Lab Assignment
s
)

June
4


Introduction
, Chapter 1


June
5


Chapter 2/3

June
6


Chapter
3/4

June
7


Chapter
5

June 1
1

Chapter
5
/
PRESENTATIONS BEGIN

June 1
2

Lecture Exam I
/
Chapter
6

June 1
3

Chapter
7

June 1
4

Chapt
er 8/
Lab Exam I

June
18

Chapter
8

June
19

Chapter
12

June 2
0

Chapter 1
3

June 2
5

Chapter 1
4

June
2
6

Lecture Exam II
/Chapter 1
5

June
2
7

Chapter
15
/1
6:

Last Day to Drop

with a "W" is June 27

Ju
ne

2
8

Chapter
1
7

July 2


Chapter
20/21

July
3


Chapter 2
1/22
Compr
ehensive Lab Final

July
5


Comprehensive Lecture Final Exam



Lab Assignments will be given on a daily basis.