CENG 109 Biotechnology and Its Business Opportunities

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22 Φεβ 2013 (πριν από 4 χρόνια και 7 μήνες)

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Announcement


Students from Engineering School: pick up a
Red

card

Students from Science School: pick up a card

Students from Business School/Dual Degree Program:
pick up a
Blue

card

CENG
109

Biotechnology and Its Business Opportunities

Class
1

Outline of this class


Course matters


Course perspectives


Grouping exercise


Review jargons in biological information


PRS demonstration


Course preview




CENG
109
Teaching Staffs


Instructor: Prof. Ying Chau
(keychau@ust.hk)

Office hours: Tuesday
9
-
10
a (by appointment)
Rm
4551


Teaching assistants:


Yuki (zhongy@ust.hk)


Cassie (joleeli@ust.hk)


Stephen (stepheny@ust.hk)




Course Perspectives

Overview

Case

What is this course about?


Gives an introductory overview of
biotechnology in the medical
-
related areas


Discusses past history, current status and
future outlook


Explains basic technologies


Addresses windows of business opportunities


Uses case
-
study format to highlight
developments representative of the industry


Invites speakers to give first
-
hand stories



The Recurring Theme

Unmet

Health Care
Needs

of the
Society

Innovations

from

Modern
Biotechnology


Commercial

Opportunities


An Engineering Approach



Engineer is derived from the Latin word
“ingenium”, meaning “invention”



Engineering is the art of directing the great
sources of power in nature for the use and
the convenience of people


-
Science and Technology Encyclopedia, McGraw Hill Education

.

GREAT Class Atmosphere


G
rasp


R
espect


E
xchange


A
sk


T
eamwork

At the completion of this course, you
will be able to….


describe the major areas covered by medical biotechnology


explain the basic technical concepts, scientific and
engineering principles


describe the opportunities and challenges faced by the
industry


analyze the potential and impact of modern biotechnology
on human health and economy


identify the key components contributing to biotechnology
of commercial interest


research topics in biotechnology and its current
development

Course materials


Course pack (Highly recommended!)


Pick up from TA at the end of this class, pay in next class


Purchase copy from Yuki (room
6113
. Email first)


Course web site
http://teaching.ust.hk/~ceng
109
/index.htm


Reserved for
2
-
hr loan in library


“Introduction to Biotechnology” by Thieman


“Biotechnology: Demystifying the Concepts” by Bourgaize, Jewell
and Buiser


CENG
109
course packs


Library course guide (Upcoming)






Assessment scheme


Class participation
20
%


Classroom involvement via PRS and group discussion


Pop
-
quizzes (based on readings and lecture materials)


Report malfunction of PRS in the same class


Homework assignments
20
%


Graded based on relevance, completeness, organization and
presentation



++,

+, or




No late submission


Mid
-
term
25
%


Multiple
-
choice and short
-
question format


Class project
35
%

There is absolutely ZERO tolerance for academic dishonesty

Grouping Exercise


5
students per group

At least two card colors

Introduce yourself!


Class project


Team formation:


5
students, two schools, one team leader


Timeline:


A step
-
by
-
step guide to help you finish the
project


Submit biweekly assignment (one per team)


First assignment due
18
/
09
: team composition
and team name


Final report and a final presentation



How do you define biotechnology?


“Integrated use of biochemistry,
microbiology and engineering sciences in
order to achieve technological (industrial)
application of the capabilities of
microorganisms, cultured tissue cells and
parts thereof”




-
Definition of biotechnology by
European Federation of Biotechnology

Storage and flow of biological information share
common traits in living things

http://aquat
1
.ifas.ufl.edu/guide/bacecoli.jpg

www.hearingvoices.com


www.wallpaperbase.com


forums.mooseyscountrygarden.com

All cells use DNA

for information
storage


Structure of a basic unit
of DNA
(DeoxyriboNucleic Acid)



www.vcbio.science.ru.nl


http://www.biologie.uni
-
hambu
r
g.de

The Language of a Gene

DNA as the replication template

library.advanced.org

Animalgenome.org

DNA is a powerful “hard disk” of
biological information


1)
Structure allows any sequence of bases


From human genome project: human contains
3146.7
million bases and ~
30
,
000
genes

2)
The duplex enables an accurate “backup”; the
complementary strand provides a template for
replication

3)
The DNA helix is stable, even in the harsh environment
of the inside of the cell

4)
The information stored inside DNA is “readable”



Central dogma governs the flow of

biological information

“Biotechnology:Demystifying the

Concepts” Bourgaize, Jewell, Buiser

The Universal Codes

Demonstration of

P
ersonal
R
esponse
S
ystem









Photo: FDA

www.karlstrauss.com

Photo: HK Dairy Farm

1

2

3

4

5

6

Which picture gives an illustration of
biotechnology?

Structure of this course


Focus on modern medical biotechnology development.


Part I: Roots of Modern Biotechnology


Classic biotechnology recombinant products and biotechnology
giants in US


Part II: Supporting technologies


Protein and drug delivery


Microarrays (e.g. DNA chips)


Part III: Future paradigms


New technologies


Biotechnology start
-
ups


University roles


Development in Hong Kong and China