HEABiosciencesMay2012BioethicsHurstPresentationx

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23 Οκτ 2013 (πριν από 4 χρόνια και 2 μήνες)

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Provocative thoughts:

teaching ethics to undergraduate
bioscience students

Dr. Tara Hurst

Nottingham Trent University

Case 1: Use of animals in
biotechnology


Module: Antibody and DNA Technology


Level: 2
nd

year undergraduates


Format: part of lecture on antibody
production

Ethical considerations: what is
wrong with using ascites?


Injection of hybridomas into
mouse peritoneum along
with adjuvants: ascites fluid.


What is ascites fluid?

Abdominal swelling

Of mice and men: ascites fluid in
humans


‘beer belly’


sign of liver
disease, other gastrointestinal
health problems


Also found in malnourished
individuals

Ethics


Use of animals: ethical treatment, aims to prevent
suffering


Three R’s:


Reduce


Refine


Replace


Using non
-
ascites methods reduces number of animals
used and reduces suffering since the initial immunisation
should have only minimal side
-
effects (as in humans)


Genetic testing


Module: Genetics and Immunology


Level: 1
st

year undergraduates


Format: question posed in advance on a hand
-
out given in a practical and discussed in the
lecture

Question 6

When is the genetic testing of
children not appropriate?

Answers to question 6


There is no single correct answer.


This represents an ethical dilemma.
Why?


Testing a child for a disease that only presents late in life could limit their
life choices.


It also precludes the child deciding for themselves: the right to know or
not
know is taken away


The recommendations of the British Society for Human
Genetics are:


Testing should be done if it will affect the treatment of the child and
better management of their condition (e.g. PKU)


If the disease presents later in life or if the condition is associated with
reproductive risks:


Testing should be approached with caution


Should preferentially be delayed until the child is old enough to
decide for themselves.