Technology Transfer in the UK

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18 Νοε 2013 (πριν από 3 χρόνια και 8 μήνες)

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ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Technology Transfer in the UK

The University of Oxford Model



Steve Cleverley PhD MBA

Managing Consultant

Isis Enterprise, Isis Innovation Ltd


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Overview



Introduction to Isis Innovation & technology transfer at the
University of Oxford



Technology Commercialization



Supporting Technology Transfer outside of Oxford



Conclusions


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Isis Innovation Ltd


Oxford Technology Transfer

IP, Patents, Licences, Spin
-
outs,

Material Sales, Outcome Questionnaires, Seed Funds,
Isis Angels Network


Oxford Expertise

Consulting, Services


Isis Consulting Business
Technology
Transfer and Innovation Management

A profitable company 100% owned by the University of Oxford


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Oxford University &

Isis Innovation Ltd


Oxford University is the oldest university in the English
-
speaking
world (founded c.1188), and a

leader in

learning, teaching
and research


Today
-

Most Powerful UK Research University

o
Research Fortnight, December 2008 Research Assessment Exercise


Highest University Research Spend in UK

o
£486 million (2009/2010)



Isis Innovation Ltd is a company 100% owned by the University
of Oxford, established in 1987


Isis
helps

researchers
who wish to

commercialise the results of
their research


A world
-
class Technology Innovation business

o
Isis 9th highest British filer of PCT patent applicant (WIPO Data, 2010)

o
Highest European University PCT applicant (WIPO Data, 2010)

Christ Church, Oxford

Ewert House, Oxford


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

University of Oxford:

Research Themes

Medical Sciences

Maths, Physical &
Life Sciences

Social Sciences

Humanities

Cancer

Chemistry for
Biomedicine

Global Governance

World Religion

Infectious Diseases,
Immunology, Pathogens

Computational Biology

Global Public Health
Issues

Applied Ethics

Diabetes, Endocrinology,
Metabolism

Climate Prediction,
Science of Energy &
Environment

Energy: Policy and
Society

Post
-
Colonial Literature

Cardiovascular Disease

Biomedical Engineering

Environment and
Business

Latin America: Culture,
Language and Literature

Genomics

E
-
Science

Politics & International
Relations

Oriental Studies: Korea,
Japan, India, Middle East

Musculo
-
skeletal Science
(joint & bone)

Bio
-
Nanotechnology

Area Studies: China,
South Asia, India

Modern Chinese & South
Asian Studies

Neuroscience

Quantative Finance

Evolutionary & Cognitive
Anthropology

Philosophy of Cognitive
Science & Neuroscience

Reproduction & Development

Quantum Information
Processing

Poverty & Refugee
Studies

Ethnomusicology

Stem Cell Biology

Universe & the Dark
Sector

Internet & Society

Science and Religion


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Resources to Support
Commercialisation

Research Services

Isis Innovation
Limited

Intellectual Property Advisory Group

UNIVERSITY COUNCIL

Four Academic Divisions

Medical
Sciences
Division

Social
Sciences
Division

Humanities
Division

Centre for
Entrepreneurship &
Innovation

Begbroke Science
Park

Oxford Entrepreneurs
Student Society

UNIVERSITY CONGREGATION

Administration

Maths, Physical
& Life Sciences
Division


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Isis Return on Investment
to the University


University Investment in Isis for Protecting Oxford IP


Financial Returns

o
Distributions back to University




o
Research Funding from spin
-
outs to University



o
Spin
-
outs Cash

o
Spin
-
outs Value





o
Oxford University Challenge Seed Fund



o
New Patents



Other, non
-
financial, benefits to the University

o
Transferring technologies to improve lives

o
Promoting good news stories from University

o
Contributing to the

Impact


of the University

o
University staff recruitment & retention

o
Managing Oxford Innovation Society



ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Oxford Research Funding
2009
-
2010 £486million


Highest University Research Spend in UK


4,700 researchers and 8,700 postgraduate students


R & D Spend by UK Companies, Oxford would be ranked 9th
2009 EU Industrial R&D Investment Scoreboard


Most Powerful UK Research University
-

2008 Research Assessment Exercise
Research Fortnight

UK Charity
£113m


31%

Research Councils
£113m


31%

UK Govt/NHS
£38m


10%

EU Govt £24m


7%

UK & Overseas Industry
£39m


11%

Other UK & Overseas Sources £40m


11%

Total

£367m

+ HEFCE

£119m


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Technology Transfer

Group (34)

Head of Group

Linda Naylor

Isis Innovation Staff


Oxford University
Consulting (6)

Head of Group

Andrew Goff

Project Managers


Susan Clark

Gurinder Punn

Dr Josef Walker

Administrators

Kerry Antcliffe

Katie Bromfield

Technology Transfer

Teams

Dr Susan Gale

Dr Ruth Barrett

Dr Nikolaos Chalkias

Dr Alex Marshall

Dr Brijesh Roy

Dr Natasha Tian

Dr Rakesh Roshan

Dr Jon Carr

Dr Mark Gostock

Dr Martin Procter

Dr Bharti Ranavaya


Dr Christine Whyte

Dr Carolyn Porter


Patent & Licence
Admin Manager

Steven Bayliss

Post
-
Deal Admin

Kate Spanchak

Patent Administrator

Zuzana Weberova

Technology Transfer

Teams

Evert Geurtsen

Roy Azoulay

Dr Manjari Chandran
-
Ramesh

Chim Chu

Dr David Churchman

Dr Jamie Ferguson

Dr Andy Robertson

Brendan Spillane

Dr Paul Ashley

Dr Angela Calvert

Dr Matthew Carpenter

Dr Sarah Deakin

Andy Self

Dr Weng Sie Wong

Seed Investment
Manager

Andrea Alunni

Operations Manager

Dr Mairi Gibbs

Administrator

Jan Newell





Isis Enterprise (20)

Head of Group

Dr David Baghurst (Asia)

Steve Lee (UK)

Consultants

Ya
-
hsin Shen (HK)

Terry Pollard

Kenji Aiba (Japan)

Dr Chris Moody

Robert Swerdlow

Dr Costas Chryssou

Dr Roger Welch

Dr Giles Kimminau

Gaurav Misra

Dr Wenming Ji

Dr Steve Cleverley

Dr Sarah Macnaughton

Elena Andonova

Dr Viraj Perera

Dr Stuart Wilkinson

Eva Baltar (Spain)

Administrators

Shelagh Harrison

Kristina Gren

Staff: 74



PhD’s: 37


MBA’s: 18

Managing Director

Tom Hockaday


Administration (13)


Business Support

Marketing

Simon Gray

Barney Cullum

Renate Krelle

Dr Fiona Story

Dr Lianne Leith

Accounts

Gemma Allnutt

Legal

Paresh Jasani



Central Administration

Office Manager

Jenny Bailey

Systems Administrator

Nelson Sa

HR

Alex Allan

Viv Parry

Facilities

Jane Tarry

Reception

Isabel Lavis


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Academic axis

£
-
> Research

3D


Spin
-
out

2D


Licence, Consulting

Acting as Multi
-
dimensional
Intermediaries

Investor axis

£
-
> £££

Commercial axis

Research
-
> £


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

International
Intermediaries


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Intellectual Property
Policy
(from October 2000)


University claims ownership of all employees’ and students’ IP rights
resulting from University research activities



The University
assists

those researchers
who wish to

commercialise
their research

o

by patenting, licences, spinout companies & consultancy



Researchers share the benefits

o
Royalty shares from licences

o
Equity in spinout companies

o
Income from personal consultancy


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Transfer of Intellectual
Property

Government

Charities

Industry

Assignment of intellectual
property rights

Research

funding

source

Inside the University

Outside the University

Research Services

Includes: IP Rights

Management Team


70 Staff

85% Graduates

33% Post grad degrees

Isis Innovation

70 staff

75% Graduates

50% Science doctorates

Spin
-
outs

Licences

Consulting

Route to
market


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Year Ending Mar:
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
University
Investment £m
£1m
£1m
£1m
£1m
£1m
£1.2m
£1.2m
£1.2m
£1.2m
£2.5m
£2.5m
£2.5m
Staff
17
21
23
34
36
36
36
37
44
54
65
68
Open Projects
319
415
476
629
725
764
784
841
978
1112
1182
1321
Patents filed
(pa)
55
63
82
65
52
55
57
49
68
64
73
66
Licence Deals
(pa)
21
36
42
37
31
38
45
50
74
69
93
107
Consultancy
(pa)
34
50
48
59
89
102
151
157
185
Spin-outs (pa)
6
8
8
7
3
4
6
7
4
4
3
4
Annual T/O £
£0.9m
1.2m
1.7m
2.0m
2.3m
2.7m
2.9m
3.6m
4.8m
5.6m
7.4m
8.4m
Isis Innovation

2000
-
2011


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

The Technology
Transfer Process


Supports technology transfer from initial invention disclosure through to
commercialization and post
-
deal support



Understanding of both the technology and the commercial market is crucial to success

Identify

Internal

marketing

Ownership

Evaluation

Protect

Patenting

Patent

strategy

Protection

Market

Overview

Customer

targets

Promotion

License

Valuation

Negotiation

Legalise

Post Deal

Billing

Distribution

Re
-
negotiation


Spinout

Translate

Proof
of

concept

Development

Endorsement

Planning

Fundraising

The Team



ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Bridging the Funding
Gap

Oxford University Challenge Seed Fund


Launched with £4m in 1999


University provided £1m; HM Treasury,
Wellcome
, Gatsby £3m


£5.7m invested in 102 projects


development, seed equity


Resulting in Equity stakes in 31 spin
-
outs, 4 completed licensing deals & 33
active technology projects. These 31 spin
-
outs have attracted £80m
seed/venture investment


Isis Angels Network


Business Angels, Seed/Venture Capital


100 members


Events, No Charges


Oxford Invention Fund


Donations to the University of Oxford as part of Oxford Thinking, the
University’s overall fund raising Campaign


Invest in development of new technologies and innovation from Oxford






ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners


Market Analysis to identify opportunities for technology


Field of use


Exclusivity


Strength and breadth of patent


Geographic limitations

o
One market or multiple markets?

o
Single technology or bundle of technologies?

What is the best route to market?

Spin out

(form a new company)

License

(to an established company)

From IP to Marketing
Strategy


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Technology Licensing


Total net Researchers University Department Isis
revenue personally General Fund Funds Innovation

to £72k

60% 10%*

0%

30%

to £720k 31.5% 21%

17.5%

30%

over £720k 15.75% 28%

26.25%

30%

* pays National Insurance
employment tax


Licensing out of University of Oxford Intellectual Property
Rights


Isis currently manages 1,320 Patents & Patent Applications; and 330 active licensing deals


Technologies marketed to Oxford Innovation Society Members and then other companies


License
partners selected on


Resources and intent to develop technology to market


In healthcare, awareness of access of final products to developing countries


Royalties


Patent budget £2.5m per annum & royalties


Isis pays patent costs & recovers these from royalties


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Oxford Spin
-
outs

(post 2000)

2000
7
Third Phase, Mindweavers, Oxford BioSignals, Oxford BioSensors, TolerRx,
OXIVA, Pharma DM
2001
7
OxLoc, Oxford Bee Co, Oxford Ancestors, Novarc, Oxford ArchDigital, Natural
Motion, Inhibox
2002
9
Pharminox, Minervation, Oxford Biomaterials(Spinox), Zyentia, Oxitec, Oxford
Immunotec, Oxford Risk, GlycoForm, BioAnalab
2003
4
Summit(Vastox)*, ReOx, Riotech, OCSI
2004
4
Avacta(OMD)*, G-Nostics, Surface Therapeutics, EKB Technology
2005
5
Oxford Nanopore Technologies, Oxford RF Sensors, Oxbridge Pulsars, Celleron,
Oxford Catalysts*
2006
7
TDeltaS, Oxford Medistress, Particle Therapeutic, Aurox, Oxford Advanced
Surfaces*, Cytox, OxTox
2007
4
Eykona Technologies, Clinox, Oxford Biodynamics, Crysalin
2008
4
Semmle, Oxford-Emergent TB Consortium, Navetas(ISE), Organox
2009
3
Oxford Financial Computing, Zyoxel, Oxford Yasa Motors
2010
4
OxEms, Kepler Energy, IXO, Oxford PhotoVoltaic
2011
[4]
Oxyntix, Oxtexs, Oxford Multi Spectral, Oxford Imaging Detectors
Total external investment to date in 62 spin
-
outs since 2000:
£326m

£41m 1st round Seed/Business Angels


average amount invested £850k; 1/3
rd

> £1m invested.

£285m follow
-
on Venture/Institution Capital


* stock exchange listing


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Oxford University
Consulting

Helping academics identify and manage
consulting opportunities.

Supporting Departments in arranging
external services (including consultancy)
work.

Providing external organizations with access
to University expertise & resources.


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Begbroke

Science
Park



Owned & operated by Oxford University, 5 miles north from the city centre



University research labs;



University Supercomputer operated by e
-
research centre



Business incubator & premises for new companies



Central meeting room and café


Spin
-
outs on site:



Prolysis
/Biota Europe



Oxford Gene Technology



Oxonica



Oxford Advanced Surfaces



Oxford
Biodynamics



Particle Therapeutics

University Departments
of Engineering Science &
Materials

Centre for
Innovation
& Enterprise


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Oxford &
Entrepreneurship


Oxford Centre for Entrepreneurship & Innovation

o
Within the
Saïd

Business School

o
Development of the Oxford Science Enterprise Centre, est. 2000

o
Brings together innovators from across the world, as well as the high
-
tech companies
based around Oxford

o
Building a Business,

o
The SBS Venture Fund



Oxford Entrepreneurs


Student Society

o
‘Idea Idol’ competition

o
Ideas to Market

o
Changemaker

speaker series

o
Enterprising Women speaker series

o
Emerging Markets speaker series





ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Culture Change &
Making Connections

University
entrepreneur
culture

Business &
professional
environment


Universities and Businesses are very different; a university is not meant to be like a
company, nor a company designed to be like a university; remembering this helps when
trying to bring them together


The ideas are in the University; if University provides strong TT resource, the cultures
can be connected and ideas transferred


If the University doesn’t lead, the University may not receive its share of the benefits


Technology is a cost; you don’t make money out of technology; you make money out of a
business that successfully commercialises technology

University technology transfer resource


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Layers in the Innovation
Ecosystem

University People


Researchers, TTO, Administrators

Professional advisers


patent attorneys, lawyers,
accountants, banks, commercial property managers,
pr, head
-
hunters, consultants, students, journalists

Innovative companies, investors, entrepreneurs,

Other universities


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

We link technology providers with technology seekers











Often with support from governments, research funders etc.

Isis Enterprise


Maturity

ideas


products


companies

TRL

1 2 3 4 5 6 7 8 9 10


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Technology Transfer
Partnerships

Building a
disclosure
pipeline

Evaluating
projects

Validating
commercialisation
plans

Translating
research into
products

Finding
commercialisation
partners

Building
spin
-
out
businesses

Mentoring
& training
staff

...building on client’s existing capabilities

…maximising the potential of commercialisation pipelines

Aston University

Liverpool University

Oxford Brookes University

Keele

University

NERC


Leadership or Supportive approaches


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Technology Transfer
Training


We deliver
practical
, bespoke training in all aspects of technology transfer and innovation
management


Our technology transfer process:









Identify

Internal

marketing

Ownership

Evaluation

Protect

Patenting

Patent

strategy

Protection

Market

Overview

Customer

targets

Promotion

License

Valuation

Negotiation

Legalise

Post Deal

Billing

Distribution

Re
-
negotiation


Spinout

Translate

Proof
of

concept

Development

Endorsement

Planning

Fundraising

The Team


Spain

Serbia

South Africa


Mexico

Taiwan

China



ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

International

Programmes


Bulgaria

o
Participating in a national infrastructure programme to help Bulgarian scientists
and engineers commercialise their research

o
In conjunction with the
Eurocopter

Offset Programme



Russia

o
Leading a regional international commercialisation programme in the Tomsk
region of Siberia

o
Includes an executive education programme (in Oxford and Tomsk)

o
Supported by the regional government and
Rusnano



Croatia

o
Supporting an EU programme to review the technology transfer capabilities of
several of Croatia’s leading universities



Case Study


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

Conclusions

How Isis Works

Universities


Technology Transfer is a good thing

o
Part of University purpose; may
make money for University and
researchers


It does not happen on its own

o
You need to invest resources in
People, Patent budget, Proof
-
of
-
Concept


You need a policy framework

o
Who owns the inventions; who
shares the rewards


It takes a long time

o
So start and do not stop.

Business

o
Access to technologies, resources and
expertise

o
Help understand universities

o
Help your business innovate


Investors

o
Source of investment opportunities

o
Home for entrepreneurs


Government

o
Stimulates innovation and enterprise

o
Improves society


ARTEV Management Platform


Intellectual

Asset

Management at
Universities

ARTEV Consortium Partners

www.isis
-
innovation.com

Nov 11

Steve Cleverley PhD MBA

Managing Consultant

Isis Enterprise




Tel: +44 (0) 1865 280849

s
teve.cleverley@isis.ox.ac.uk

www.isis
-
innovation.com