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HC70A Winter 2006

Genetic Engineering in
Medicine,

Agriculture, and Law

Professor Bob Goldberg



Class Announcements

2/9/06

Reminder

Take
-
Home Exam

& Oral Mid
-
Term Exam


Questions Out
-

2/14
(Tuesday)


Questions Due
-

2/28


Mid
-
Term Oral
-

2/28

Discussion 2/15/06


When Science Takes the
Witness Stand
--

DNA Testing
& Criminal Cases


Play
--

In Law School

Moot Court Room


Come Prepared For Your Role


& Science Background


Will Be Filmed and Webcasted

Reading For Court Room Discussion & Play


When Science Takes the Witness Stand
-

Peter
Neufeld (Innocence Project)
-

MAIN ARTICLE


Perspective on DNA Testing & Forensics
-

Rothstein


The DNA Detectives (Newsweek)


American Society of Law, Medicine, & Ethics

DNA Forensics and Civil Liberties Workshop Summary


Daubert Standard


Listen to the Experts
--

Daubert, Frye, and California


Science on Trial in The Courtroom
-

Chapter 11
-

Introduction to Forensic DNA Analysis


Population & Evolutionary Genetics
-

Chapter 29
-


Introduction to Genetics

Review of Last Lecture


What is the Structure of DNA?


What is the Anatomy of a Gene?


How Are Genes Organized on
Chromosomes?


How Can Regulatory Information Be Used
To Create New Body Architecture?


Engineering New Animal Body Forms
-
It’s
All in the Regulatory Switches!!


How Far Should We Go?

Today


How Are Genes Replicated?


Genetic Engineering & The PCR Revolution!


Mutations, Pedigrees, & Genetic Diversity


Genes Proteins


Gene Activity in Bacteria & Eukaryotes


One Gene
-
Many Proteins
-
Relevance to
Humans


The Universal Genetic Code


DNA vs. RNA


Yo
-
It’s All in the Sequences!