CCFRA Applications of Bioinformatics in the Food Industry - CORDIS

earthsomberΒιοτεχνολογία

29 Σεπ 2013 (πριν από 3 χρόνια και 10 μήνες)

110 εμφανίσεις


JJD 2005
C C F R A

JJD 2005
C C F R A
Modern Human Food Industry
Modern Human Food Industry
Proteins
DNA
Sugars/
Carbohydrates
Flavours
Enzymes
Microorganisms
Functionality
Sensory
Breeding
programmes
Probiotics &
prebiotics
Disease
control
Nutrition
GMO
Allergens
Shelf
-
life
Medicinal
Genetics

JJD 2005
C C F R A
Initiatives/technologies requiring
bioinformatics 1
Micro
-
organisms
(bacteria, yeasts)
identification; natural pops; traceability; food poisoning,
spoilage, hygiene or processing; probiotics
“Omics”(genomics/proteomics/nutriomics)
gene regulation; disease prediction; protein
interactions, functionality; enzymes; allergenicity;
dietary affects; probiotics, prebiotics

JJD 2005
C C F R A
Initiatives/technologies requiring
bioinformatics 2
Protein analysis
interactions between proteins and other proteins, drugs
or antibodies; functionality; protein structures,
predictions of 3’ or 4’, modelling, prediction from
sequences (DNA or amino acid)
Profiling
use of DNA, protein or other metabolites to identify
meat, fish, fruit, veg, cereals, microbes samples
Breeding programmes
plant & animal, GMO, genetics

JJD 2005
C C F R A
Types of data generated
Sequence data
DNA & protein
Microarray data
expression data from DNA, protein, sugars
Chromatography/electrophoresis
1
-
D gels of DNA or protein profiles (fingerprints); 2
-
D
gels; MS/MS technologies

JJD 2005
C C F R A
Microarray data
(DNA & protein)

Generates huge
numbers of data
points
.

e.g. Each array can have up to 50,000 data points so a small
10 array experiment = 500,000 data points

Useful for gene expression or detection/screening
methods
Genetic detection/screening

some “biochips” starting to emerge, e.g. bioMérieux

standard chips being used for animal or plant breeding
programs to screen F1 crosses for desired genes

JJD 2005
C C F R A
Microarray data
Gene expression
Currently applied to answer questions relating to…

Effects of growing conditions

e.g. “How
does drought affect this cereal variety
?”

Animal/plant breeding

e.g. “What
effects does a cross have on gene activity
?”
Could be used to address other questions relating
to, for
example…

Crop ripening and storage etc

JJD 2005
C C F R A
Microarrays
Microarrays

JJD 2005
C C F R A

Analysis of protein structure and interactions or
relationships with the aim of…

improving functionality, e.g. bread making

reducing allergenicity while conserving functionality

improving enzyme activity

predicting function of unknown proteins based on
structure or sequence

JJD 2005
C C F R A
Applications of Bioinformatics
Applications of Bioinformatics
in the Food Industry
in the Food Industry
The huge amounts of data that can be generated from
these outlined projects will make bioinformatics an
important area in the food industry.
Although brief I hope I have provided ideas about some
of the potential uses of bioinformatics in the food
industry
-
food for thought at least.
I have tried to avoid overlapping with the other workshop
areas. Hopefully these will come out in the final
discussion this afternoon.