Industrial Biotechnology

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6 Δεκ 2012 (πριν από 4 χρόνια και 10 μήνες)

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Ventura College

Funded by the EWD of the California Community Colleges


SCRC regional
community colleges


K12 educational
institutions


Neighboring biotech
companies


Enrolled students


Instructors


Incumbent workers


Displaced workers


Community
organizations

“To provide training and educational support in
biotechnology with the goal of facilitating employment
of individuals in biotechnology related fields.”

Tricia
Fausset

4/24/09


The use, creation, or manipulation of living
organisms to make or improve industrial,
agricultural, and medical products and to
solve problems.

Tricia
Fausset

4/24/09


CLASSIC EXAMPLE
-
BAKING BREAD




The living organism “yeast” feeds off of the
other ingredients in the bread such as sugar
and flour. As the yeast grows, it gives off a
gas (carbon dioxide) and this gas is trapped
within the “walls” of the dough. So, the
dough expands upward and outward
-

it rises!
Baking the bread inactivates the yeast but
leaves behind the bread.

Tricia
Fausset

4/24/09

Tricia
Fausset

4/24/09


CURRENT EXAMPLE
-
ALTERNATIVE FUEL



Companies are using yeast as “factories” to
produce products of interest. The yeast can
be fed particular components so that the
“waste” they produce can be purified. An
example of this “waste” is a particular
compound found in sugarcane that may be
an alternative fuel to gasoline.

Tricia
Fausset

4/24/09

Tricia
Fausset

4/24/09


CLASSIC EXAMPLE
-
LADYBUGS



Ladybugs have been used for years as a
natural pesticide in the garden. These little
creatures feed on annoying aphids in the
garden and eliminate the need for chemical
spraying of plants and flowers.

Tricia
Fausset

4/24/09

Tricia
Fausset

4/24/09


CURRENT EXAMPLE
-
INTERNAL PESTICIDES



Corn crops that are resistant to pests from
the inside out. Their DNA has been modified
so that it contains information that, when
expressed, makes the corn unpleasant to
certain insects. These insects then leave the
crop alone.

Tricia
Fausset

4/24/09

Tricia
Fausset

4/24/09


CLASSIC EXAMPLE
-
TETANUS VACCINE



This common childhood vaccine has been in
use since the early 1940’s. Tetanus bacteria
produce a toxin that can be isolated from the
bacteria and then heat
-
inactivated. The toxin
is then injected into humans where an
immune response results in protection
against the toxin.

Tricia
Fausset

4/24/09

Tricia
Fausset

4/24/09


CURRENT EXAMPLE
-
PHARMACEUTICALS



Companies can modify bacteria to produce
products of interest. Rather than making
medicines in a chemical lab, these living
organisms release the desired compounds
during growth. The pharmaceutical company
can isolate and purify the products and use
them just as if they were
synthsized

in the
laboratory.

Tricia
Fausset

4/24/09

Tricia
Fausset

4/24/09

DNA


RNA


Protein

It’s a little like the relationship

Seed


Tree


Fruit

Tricia
Fausset

4/24/09


Isolate and analyze DNA


Manipulate DNA


Inserting DNA into bacteria or other cells


Growing cells


Harvesting or isolating protein from cell fluid


Purifying the manufactured product


Regulatory documentation of all processes


Clinical trial monitoring



Tricia
Fausset

4/24/09


Research Associate


Lab Technician


Manufacturing Operator


Systems Analyst


Regulatory Affairs Specialist


Clinical Trials Monitor


Computational Biology Specialist


Tricia
Fausset

4/24/09

VCEDA

Tricia
Fausset

4/24/09

Tricia
Fausset

Director

Central Coast Biotechnology Center

Ventura College

4667

Telegraph Rd.

Ventura, CA
93003

805.648.8977

(Phone);
805.648.8988

(Fax)

pfausset@vcccd.edu

www.ccbcweb.net