HEPATOPROTECTIVE

HEPATOPROTECTIVE


BY


SHRAVAN PASWAN

paswanshravan@gmail.com







ADVANCE INSTITUTE OF BIOTECH &
PARAMEDICAL SCIENCES,

KANPUR

HEPATOPROTECTIVE

INDEX



(1.0) Introduction



(2.0) Use of hepatoprotective



(3.0) Drugs avilable in market



(4.0) Market analysis



(5.0) Conclusion



(6.0) Reference


INTRODUCTION


Hepatoprotective neutralizes all kind of toxins and poisons
from food, water, air and medications, all sources of
detrimental effects on the liver. Counteracting those hard
to avoid poisons and protecting one of the body's most
important organs.


Alcohol users in particular find hepatoprotective helpful in
maintaining a healthier liver. It also helps those taking
necessary allopathic medications to protect themselves
against the damaging hepatoxic side effects.


The most widely used hepatoprotective agent used in the
Western World is

silymarin, a constituent purified form
Silybum marianum.




Silymarin an active Hepatoprotective in Alcoholic Liver
Disease

USES OF HEPATOPROTECTIVE



Hepatoprotective’s are widely used in various
hepatotoxicities like:
-


(a) Alcoholic liver disease.


(b) Pre
-
cirrhotic conditions and early cirrhosis.


(c) Protein energy malnutrition.


(d) Loss of appetite.


(e) Radiation and chemotherapy
-
induced liver damage.


(f) Viral hepatitis.


(g) As an adjuvant with hepatotoxic drugs.


(h) A valuable adjuvant during convalescence and
prolonged illness.


MARKET ANALYSIS



Liv
-
52
-

World's #
1
selling liver support formula
Recommended for Cirrhosis, Hepatitis, Fatty liver and
Elevated liver enzymes.


It was introduced in
1955
by Himalaya Herbal Healthcare.
Since then, it has been sold worldwide and is recognized by
thousands of health professionals as one of the most
effective liver formulas, with beneficial effects reported in
over
300
studies on a variety of cases.


In the Western World is silymarin, a constituent purified
form Silybum marianum having high market value

as
compare to other.


Milk thistle, in
2001
products ranked
12
th in the list of
supplements sold in the US surpassing
7
million dollars.

DRUGS AVILABLE IN THE
MARKET




LIV
-
52/TAB,SYRUP,DROPS



Liv52 ensures optimum liver function through the
protection of the hepatic parenchyma, and by way of its
potent antioxidant properties.


Liv
-
52/ Liver Care neutralizes all kind of toxins and
poisons from food, water, air and medications, all sources
of detrimental effects on the liver.


Alcohol users in particular find Liv
-
52/LiverCare helpful
in maintaining a healthier liver.


Liv
-
52 is a unique, all
-
natural, complex multi
-
ingredient
formula. It is safe and effective in protecting the liver
against harmful toxins from drugs, alcohol, food and
water.


MARKETED PRODUCTS


MARKETED PRODUCTS OF SILYMAMN




DRUG MANUFACTURING COMPANY



SIVYLAR (Tab) RANBAXY



LIVTOP (Tab) COMEL



RELIV (Tab) RED BOSS



COMBINATION DRUG




LIVAGE (Cap) ARISTO



LIVOSIP (Syp) CIPLA



JETOSITOL (Tab) J&J



HEPACOL (Syp) BIODRUG



COMPANIES MANUFACTURING
HEPATOPROTECTIVE
DRUGS






Shine Star ( Hubei ) Biological Engineering Co., Ltd



M/S Madley Pharmaceuticals Ltd., Mumbai


Ningbo Jeing
-
Yuan Biotechnology Co., Ltd.s


India Biocon India Ltd., Karnataka.


Wilson Drugs & Pharmaceuticals Pvt. Ltd [India]


Ansar Drug Laboratories, Surat


Acis Laboratories, Kanpur


Allen Laboratories, Kolkatta



Dattatraya Krishan Sandu Bros., Mumbai


Herbo
-
med (P) Ltd., Kolkatta


The Himalaya Drug Co., Banglore

GRAPHICAL REPRESENTATION


PERCENTAGE SALE OF HEPATOPROTECTIVES
THROUGHOUT WORLD


PERCENTAGE OCCURANCE OF
HEPATOPROTECTIVES THROUGHOUT WORLD

CONCLUSION


From the last two decades , pharmacy was rather more of
an art than a sciences & progress was leisurly, but by time,
the production and use of drug had begun which was to
burst into an explosion of effort in succeeding years was to
revolutionize the practice of pharmacy.


At the very outset let me state that pharmaceutics &
pharmacology is a tool of whose potential appears limitless
the word pharmaceutics is used in pharmacy &
pharmaceutical sciences to encompass many subject areas,
which are all associated with the steps to which a drug is
subjected towards the end of its development my project
has undergone on one such topic of pharmaceutical
marketing of Hepatoprotective.


In the project I have tried to dealt with the various
Hepatoprotective drugs like its introduction, uses, market
research, global demand etc.

REFERENCE



Howland,R.D. , Myce,M.J , Horvey,R.A , Lippincott’s
pharmacology , B.I.Publication Pvt.Ltd. , edition
-
4
th ,
reprint
-
2004
, page no.
436
-
440
.


Barar,F.S.K. , Essential of pharmacotherapeutics ,
S.Chand & Company Ltd. , edition
-
7
th, reprint
-
2007
,
page no.
558
-
562
.


Brunton,L.L. , Lazo,J.S.,Goodman & Gilman’s ,The
pharmacology basis of therapeutics , McGraw
-
Hill
Medical Publishing Division , edition
-
11
th, pageno.
774
-
778
.


Boon,N.A. , Colledge,N.R., Walker,B.R., Davidson’s
principles & practice of medicne, Churchill Living Stone ,
edition
-
20
th , reprint
-
2006
, page no.
975
-
987
.



www.google.com
\
liv
52
\
alcoholic
-
liver
-
disease
-
liv
52
.


www.google.com
\
showroom
\
herbal_health_ food.


www. google.com
\

Anti
-
inflammatory and
Hepatoprotective Activities.


www. google.com
\

Hepatoprotective and Inhibition of
Oxidative Stress in Liver.



THANK’S