ChE 380 - Department of Chemical, Biological & Pharmaceutical ...

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23 Οκτ 2013 (πριν από 4 χρόνια και 17 μέρες)

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ChE 380


Introduction to Biotechnology

Fall 2013


Instructor




Kshitiz Chaudhary
, Ph.D.


E
-
mail:




kc323@njit.edu


Office Hours:




By appointment only, Thu, 5:00 pm


6:00 pm


Catalog Description:

ChE 380
-
101


Introduction to Biotechnology
.
Prerequisites: Chem 122 or Chem 126. Basic
principles of molecular biotechnology with selected examples of applications.

These applications
include, but are not limited to, the production of chemical and biological materials

and the
development of processes encountered in the Biotech industry.


Course Objectives:

1.


To identify structures of prokaryotic and eukaryotic cells

2.


To describe microbial nutrition, growth and metabolism

3.


To describe DNA replication, RNA and
protein synthesis

4.


To describe Mutations, genetic manipulation and DNA uptake

5. To explain some basic applications of Biotechnology



Textbook(s):

1.

Introduction to Biotechnology, 3
r
d

Ed.

(2013)
, by William J. Thieman and Michael A.
Palladino, Pearson/Be
njamin Cummings, New York.


Grading scheme:

Project


20%

Exam


40%

Final


40%




Policies:


1.

Students are responsible for the material covered in class. Regular class
attendance

is expected.

2.

Make
-
up exams

and “
incompletes
” may be given under
extraordinary
circumstances and at the sole discretion of the instructor. Regular class
attendance is expected.

Schedule:


Sept 5

Historical background

-

Chapter 1, Sections 1.1, 1.2 and 1.3



Sept 12

Cell structure

-

Chapter 2, Section 2.1

Microbial nutrition, growth, and metabolism

-

Lecture notes


Sept 19

Introduction

to genes and genomes

-

Chapter 2, Section 2.2: The Molecule of Life


DNA Structure

-

Chapter 2, Section 2.2: The Molecule of Life


What is a Gene?

-

Chapter 2, Section 2.3: What is a Genome?


Sept 26

DNA replication, RNA and protein synthesis

-

Chapter 2, Section 2.3: DNA replication

-

Chapter 2, Section 2.4: RNA and protein Synthesis


Oct 3

Mutations, genetic manipulation, DNA uptake, and applic
ations

-

Chapter 2, Section 2.5

-

Chapter 3, Section 3.1, Introduction to Recombinant DNA Technology and DNA
Cloning


Oct 10

Restriction enzymes/plasmids, gene cloning/analysis

-

Chapter 3, Section 3.1, Restriction Enzymes and Plasmid DNA Vectors

-

Ch
apter 3, Section 3.1, Bacterial transformation

-

Chapter 3, Section 3.3, Polymerase Chain Reaction


Oct 17

Applications of Recombinant DNA Technology, Genomics and Bioinformatics

-

Chapter 3, Section 3.4, Gel Electrophoresis, DNA Sequencing, Gene Expression

-

Chapter 3, Section 3.5, Whole genome sequencing, Bioinformatics, Human genome
project


Oct 24

Protein as products


-

Chapter 4, Section 4.1, Proteins as products

-

Chapter
4, Section 4.3, Protein production

MID
-
TERM EXAM


Oct 31

Microbial biotechnology, microorganism, and applications


-

Chapter 5, Sections 5.3

-

Lecture notes


Nov 7

Microbial b
iotechnology, Vaccines,
Micobial Genomes, Biofuels

Chapter 5, Section 5.4, 5.
5 and 5.6


Nov 14

Plant

biotechnology

and Applications

-

Chapter 6, Section 6.3

Animal biotechnology and applications

-

Chapter 7, Sections 7.2
, 7.3



Nov 21

Medical Biotechnology

-

Chapter 11, Section 11.1, Detecting Human Diseases

-

Chapter 11, Section

11.3, 11.4, Gene Therapy, Stem Cell Technologies



Dec 5

Examples from the Biotech industry

-

Lecture notes



Dec 19

Final Exam




The NJIT Honor Code and standards of
academic integrity

will be enforced in this
course. Any violation will be brought t
o the immediate attention of the Dean of
Students.