INTRODUCTION TO BIOTECHNOLOGY

breakfastcorrieΒιοτεχνολογία

22 Φεβ 2013 (πριν από 4 χρόνια και 6 μήνες)

193 εμφανίσεις

INTRODUCTION TO
BIOTECHNOLOGY SERVICES

Introduction to Biotechnology Standard


Students will
evaluate career
choices in the field
biotechnology.

What is a Biotechnologist?


www.thefunworks.org



Biotechnologists
-

Listed under
Technology

Careers in Biotechnology


Microbiology


Toxicology


Biomedical Engineering


Genetics


Forensics





Essential Question

How will
discoveries in
Biotechnology
affect my life?

Microbiology




Environmental Microbiology



Food Microbiology



Industrial Microbiology



Medical Microbiology



Veterinary Microbiology




Career Information:

U.S. Department of Bureau of Labor Statistics

www.bls.gov





Toxicology

What is it?

The study of the adverse effects of chemicals on
living organisms.



What happened to Michael Jackson?

..
\
Michael Jackson Toxicology Report video.mp4




Toxicology

Examples of chemicals that may have adverse
effects on living organisms:


Pesticides


Poisons


Drugs, when used inappropriately


Industrial chemicals




Exploring Toxicology


Upon completion of this unit,
you will explore and present
information learned about the
careers in the field of
Toxicology.

Toxicology Research


Work in Pairs

Time to Complete Presentation


2 Days

Research Topics


What is Toxicology?


Where Do Toxicologists Work?


Part 1
-

Job Market Survey


Part 2
-

Research Foundations


Part 3
-

Regional Distribution of Jobs


How Do I Prepare for a Career in Toxicology?


Colleges Offering Degrees in Toxicology



Research the field of Toxicology


Paired Grouping Assignment


First work in pairs to research questions on your
handout.

REFER TO YOUR PRESENTATION RUBRIC

as you

prepare for your presentation.


Toxicology Research Sources

General Information on Toxicology:

Society of Toxicology

http://www.toxicology.org/ai/apt/careerguide.asp

College Search for Toxicology:

Google

www.google.com





Biomedical Engineering


Describe computer applications and
biomedical devices in healthcare.


1. DEKA arm video




..
\
DEKA robotic arm video 1.mp4

2. Research Engineering Company: DEKA

http://www.dekaresearch.com/deka_arm.shtml








Genetics





You will explore the structure of DNA and its
relationship to the cell.













This image is from


http://www.childrensmuseum.org/teachers/unitsofstudy/biotechnology/lesson3.htm

This is a great website for learning about genetics and biotechnology.

THE

HUMAN GENOME

DNA Seperation


Activity
:

Group Lab Experiment

Separating DNA


Genetic Inheritance of Disease


You will learn how to create and
interpret a Punnett square and a
pedigree chart showing the
probability of inheriting a genetic
disease.




Who uses a Punnett square or a
pedigree chart?


Medical Geneticists


Genetic Counselors


People are referred to genetic professionals
because of concern about the presence of a
genetic condition in a family member.


Pedigree analysis helps families understand
the probability of reoccurrence of a
genetically inherited disease.

What is a Punnett square?


A
Punnett

square

is a
mathematical tool displayed as
chart which shows possible
gene combinations occurring
in children of the same
biological parents.














,


Creating a Punnette square

for


Mr. and Mrs. Ram’s Family

Mr. Ram’s

genotype
contribution

Mrs. Ram’s genotype contribution

A

A

B

B

BA

BA

BA

BA

Ram

children’s

genotype

possibilities

What is the probability that the Ram’s children

will share the same genotype (the BA genotype)?



ANSWER


The probability of the Ram
children sharing the same
genotype is 100%.


All the Ram children have the
BA genotype.


Another way to present genetic information
shown in a Punnett Square

Father

Mother

Son

Daughter

Daughter


Family Tree


THIS CHART IS CALLED A PEDIGREE CHART

Son

Rhonda Ram gets married!


One of the Ram’s children,
Rhonda, has grown up and gotten
married. She and her husband
have four children. Let’s look
back at the Punnett square for
the Ram family.


Creating a Punnette square

for


Mr. and Mrs. Ram’s Family

Mr. Ram’s

genotype
contribution

Mrs. Ram’s genotype contribution

A

A

B

B

BA

BA

BA

BA

Ram

children’s

genotype

possibilities

The Ram’s daughter Rhonda




Let’s create a Punnett square for Rhonda’s
family
.


Rhonda’s genotype: BA


Rhonda’s husbands genotype: AA

Draw the

Punnett

square

grid and

fill Rhonda’s

family

genotypes.

Answer these
questions
:



Of Rhonda’s
four children,
what are

the
odds of having
children with an
AA genotype?




What are the
odds of having
children with an
AB genotype?











Punnette Square

for Rhonda Ram’s Family


Rhonda’s
husband’s

genotype
contribution

Rhonda’s genotype contribution

B

A

A

A

Rhonda’s

children’s

genotype

possibilities

AB

AA

AB

AA

Of Rhonda’s four children, what are the odds of having children with
an AA genotype?

What are the odds of having children with an AB genotype?


ANSWERS


The probability of Rhonda’s
children having the AA
genotype is 50%.


The probability of Rhonda’s
children having the AB
genotype is 50%.



Inheritance of Tongue Rolling Trait

Tongue rolling is a
dominant trait

-

R

Non
-
tongue rolling is
recessive

trait


r


Example
: Mr. Plankton can roll his tongue and
he has a dominant genotype of RR.


Mrs. Plankton can not roll her tongue and she
has a recessive genotype of rr.


The Planktons plan to have four children.


Create a Punnett square to predict which of the
Plankton children will be able to roll their
tongues.

The Planktons’ Punnett Square

R

R

r

r

Rr

Rr

Rr

Rr

100% of the
Plankton

children will be
able to

roll their tongues!


Look out

Mr.
Krabbs, better
guard those
Krabby patties!

The Squidwards


Refer to your
Probability of
Inheritance Activity

Handout.


Create a
Punnett square

and
pedigree chart

for the
Squidwards.

The Squidward’s Punnet square

The Squidward’s pedigree chart

Father

Mother

Children

The Squidward children will have a 50% chance of
inheriting the disorder and 50% chance being
entirely normal.


The Patricks


Refer to your
Probability of
Inheritance Activity

Handout.


Create a
Punnett square

and
pedigree chart

for the Patricks.


Biomedical Research


You will analyze the benefits of biomedical
research using internet interactive website
resources.


What is Biomedical Research?

ACTIVITIES


1. Working in pairs: DNA and Stem Cells
-

“Stem Cell Guy”

2. As a class: Stem Cell Therapies Today
Internet Presentation








INTERNET ASSIGNMENTS


1.
Work in Pairs
: What is a stem cell?

Stem Cell Assignment: Learn.Genetics. from the
University of Utah

http://learn.genetics.utah.edu/content/tech/ste
mcells/scintro/


2.
Review as a class
: Stem Therapies
Today Howard Hughes Medical Institute at

http://www.hhmi.org/biointeractive/stemcells/Stem_Cell_Therapies/01.html


Additional ways DNA Identification
may be used



To exonerate persons wrongly
accused of crimes


To identify crime and catastrophe
victims


To identify potential suspects whose
DNA may match evidence left at
crime scenes

FORENSIC MEDICINE


What is it?


The field of medicine that interprets or
establishes the facts in criminal law cases.


You will evaluate forensic techniques used to
solve a crime.

Activity


Use DNA identification to help solve a crime.



DNA Detective: Solve the Crime
www.tryscience.org


Agarose Gel Electrophoresis


www.bio.miami.edu/~cmallery/150/gene/mol_gen.htm



More ways DNA Identification may
used


Detection of bacteria and other organisms
that may pollute air, water, soil, and food


Matching of organ donors with recipients in
transplant programs


Identification of endangered and protected
species as an aid to wildlife officials (could be
used for prosecuting poachers)


Determine pedigree for seed or livestock
breeds



Forensic Career Research

www.thefunworks.org


Biotechnologists (listed under Technology)


Forensics Specialists (listed under
Medicine/Law)


Biotechnology Career Review






Genetics

-

DNA and the discovery of the Human Genome


Microbiology



Blood typing


HHMI Virtual Lab: Bacteria ID

Toxicology

-

Problem solving: What happen to Michael?

Biomedical Engineering

-

DEKA arm: CBS 60 Minutes

Forenics

-

DNA Detective: tryscience.org

Biomedical Research
-

Stem cells and stem cell research


Review Essential Question






Share your answers to this Essential
Question.

How will discoveries in
Biotechnology affect
my life?