1. Blackburn, GM, Cohen, JS, and Todd, L. Cylic ... - Jack Cohen

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ESEARCH
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UBLICATIONS
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1.

Blackburn, G. M., Cohen, J. S., and Todd, L. Cylic Phosphate and Phosphate Triester
s a
31
P
NMR Study, Tetrahedron Lett.
No. 39:

2873, 1964.

2.

Cohen, J. S.
31
P and
1
H NMR Studies of Tetramethoxyphosphonium Hexachlorantimonate
and Related Compounds, Tetrahedron Lett.
No. 39:

3491, 1965.

3.

Blackburn, G. M., Cohen, J. S., and Todd, L. The
Synthesis of Dialkyl Phosphates from
Monoalkly Phosphonates
-

Direct Oxidative Esterification, J. Chem. Soc. (C).
239:
, 1966.

4.

Cohen, J. S., and Lapidot, A. Reduction Studies with Naturally Occurring Quinones and
their Phosphate Derivatives with Referenc
e to Oxidative Phosphorylation, J. Biol. Chem.
241:

4060, 1966.

5.

Cohen, J. S. Proton and Phosphorus
-
31 Nuclear Magnetic Resonance Studies of
Tetraalkoxyphosphonium Hexachlorantimonates and Related Compounds, J. Am. Chem.
Soc.
89:

2543, 1967.

6.

Cohen, J.

S., and Lapidot, A. Proof of the Imidoyl Phosphate Intermediate on Oxidative
Phosphorylation in
18
O
-
N,N
-
Dimethyl
-
formamide Solution, J. Chem. Soc. (C) 2320, 1967.

7.

Meadows, D. H., Markley, J. L., Cohen, J. S., and Jardetsky, O. Nuclear Magnetic
Resonanc
e Studies of the Structure and Binding Sites of Enzymes, I. Histidine Residues,
Proc. Natl. Acad. Sci. USA.
58:

1307, 1967.

8.

Cohen, J. S. Imidazole
-
Phosphate Interaction in Dimethyl Sulphoxide with Reference to
Ribonuclease Inhibitor Binding, Biochem. Bi
ophys. Res. Comm.
33:

465, 1968.

9.

Cohen, J. S., and Jardetsky, O. Nuclear Magnetic Resonance Studies of the Structure and
Binding Sites of Enzymes, II. Spectral Assignments and Inhibitor Binding in Hen
-
Egg
White Lysozyme, Proc. Natl. Acad. Sci. USA.
60:

93, 1968.

10.

Cohen, J. S. Investigations of the Binding of Small Molecules to Protein Using Information
from Nuclear Magnetic Resonance, J. Clin. Pharmacol.
9:

69, 1969.

11.

Cohen, J. S. Proton Magnetic Resonance Studies of Human Lysozyme, Nature.
223:
, 1
969.

12.

Horsley, W., Sternlicht, H., and Cohen, J. S. Carbon
-
13 Nuclear Magnetic Resonance
Studies of Carbon
-
13 Enriched Amino Acids, Biochem. Biophys. Res. Commun.
37:

47,
1969.

13.

Roberts, G. C. K., Dennis, E. A., Meadows, D. H., and Cohen, J. S. J., O
. The Mechanism
of Action of Ribonuclease, Proc. Natl. Acad. Sci. USA.
62:

1151, 1969.

14.

Cohen, J. S., Horsley, W., and Sternlich, H. The Isolation of Carbon
-
13 Enriched Amino
Acids, Biochim. Biophys. Acta.
222:

521, 1970.

15.

Cohen, J. S., Shrager, R. L
., McNeel, M., and Schecter, A. N. On
-
line Computer
-
Assisted
Analysis of 220 MHz Data of Protein Imidazole Resonances, Biochem. Biophys. Res.
Commun.
40:

144, 1970.

16.

Cohen, J. S., and Putter, I. The Isolation of Deuterated Amino Acids, Biochim. Biophys.

Acta.
222:

525, 1970.

17.

Cohen, J. S., Schecter, A., Shrager, R., and McNeel, M. Proton Magnetic Resonance
Studies of the Histidine Residues of S. Nuclease, Nature.
228:

642, 1970.

18.

Horsley, W., Sternlicht, H., and Cohen, J. S. Carbon
-
13 Magnetic Reso
nance Studies of
Amino Acids and Peptides, J. Am. Chem. Soc.
92:

680, 1970.

19.

Vanden Heuval, W. J. A., and Cohen, J. S. Gas
-
liquid Chromatography Mass Spectrometry
of Carbon
-
13 Enriched Amino Acids as Trimethyl Derivatives, Biochim. Biophys. Acta.
208:

2
51, 1970.

20.

Vanden Heuval, W. J. A., Smith, J. L., and Putter, L. C., J. S Gas
-
liquid Chromatography
Mass Spectrometry of Deuterium
-
Containing Amino Acids as Trimethylsiyl Derivatives, J.
Chromatog.
50:

405, 1970.



2


21.

Vanden Heuval, W. J. A., Smith, J. L
., and Cohen, J. S. Gas
-
liquid Chromatography and
Mass Spectrometry of Carbon
-
12 Enriched and Deuterated Amino Acids as Trimethylsilyl
Derivatives, J. Chromatogr. Sci.
8:

567, 1970.

22.

Blackburn, G. M., Cohen, J. S., and Weatherall, I. Phosphorus
-
31 NMR S
tudies of Cyclic
Derviatives of Phosphorus Oxy
-
Acids, Tetrahedron Lett.
27:

2903, 1971.

23.

Cohen, J. S. Proton Magnetic Resonance Studies of Oligopeptides Containing Aromatic
Residues, Biochim. Biophys. Acta.
229:

603, 1971.

24.

Cohen, J. S., Feil, M., a
nd Chaiken, I. Proton Magnetic Resonance Studies of the Tyrosine
Residues of Staphylococcal Nuclease Using (3,5
-
d) Tyrosine, Biochim. Biophys. Acta.
236:

468, 1971.

25.

Epstein, H., Schechter, A. N., and Cohen, J. S. Folding of Staphylococcal Nuclease:
Mag
netic Resonance and Fluorescence Studies of Individual Residues, Proc. Natl. Acad.
Sci. USA.
68:

2042, 1971.

26.

Freedman, M., Cohen, J. S., and Chaiken, I. Carbon
-
13 Fourier Transform Nuclear
Magnetic
Resonance Studies of Peptides,
Biochem. Biophys. Res.
Commun.
42:

1148,
1971.

27.

Sachs, D. H., Schecter, A. N., and Cohen, J. S. Nuclear Mag
ne
tic Resonance Titration
Curves of Histidine Ring Protons, I. Neighboring Charged Groups, J. Biol. Chem.
246:

6576, 1971.

28.

Vanden Heuval, W. J. A., Arison, B. H., an
d Cohen, J. S. Combined Gas
-
liquid
Chromatography Mass Spectrometry Study of the Bromine Oxidation of Synkavit in 18O
-
Dimethylformamide, J. Chromatog.
59:

169, 1971.

29.

Cohen, J. S., Hagenmaier, H. P., Pollard, H., and Schecter, A. N. Proton Magnetic
Reso
nance Study of the Histidine Residues of Sperm Whale and Horse Myoglobins, J. Mol.
Biol.
71:

513, 1972.

30.

Cohen, J. S., Yim, C. T., Kandel, M., Gornall, A. G., Kandell, S. J., and Freedman, M. H.
Studies of the Histidine Residues of Carbonic Anhydrases U
sing High Field Proton
Magnetic Resonance, Biochemistry.
11:

327, 1972.

31.

Cohen, P., Griffin, J. H., Camier, M., Caizergues, M., Fromageot, P., and Cohen, J. S.
Hormonal Interactions at the Molecular Level: High Resolution PMR Study of Bovine
Neurophysin
s and Their Interactions with Oxytocin, FEBS Lett.
25:

282, 1972.

32.

Schecter, A. N., Sachs, D. H., Heller, S. R., Shrager, R. I., and Cohen, J. S. NMR Titration
Curves of Histidine Ring Protons, III. Ribonuclease, J. Mol. Biol.
71:

39, 1972.

33.

Shrager,

R., Cohen, J. S., Sachs, D. H., and Schecter, A. N. Nuclear Magnetic Resonance
Titration Curves of Histidine Ring Protons, II. Mathematical Models for Interacting Groups,
Biochemistry.
11:

541, 1972.

34.

Chaiken, I. M., Freedman, M. H., Lyerla, J. R., and

Cohen, J. S. Preparation and Properties
of
19
F and Enriched
13
C
-
Labeled Semisynthetic Ribonuclease
-
S' Analogues, J. Biol. Chem.
248:

884, 1973.

35.

Cohen, J. S., J., G., and Schecter, A. N. NMR Titration Curves of Histidine Ring Protons,
IV. The Effects o
f Phosphate and Sulphate on Ribonuclease, J. Biol. Chem.
248:

4305,
1973.

36.

Feldmann, R. J., Bacon, C. R. T., and Cohen, J. S. Versatile Interactive Graphics Display
System for Molecular Modelling by Computer, Nature.
244:

113, 1973.

37.

Freedman, M. H.,

Lyerla, J. R., Chaiken, I. M., and Cohen, J. S. Carbon
-
13 Fourier
Transform Nuclear Magnetic Resonance Studies of Selected Amino Acids, Peptides and
Proteins, Eur. J. Biochem.
32:

215, 1973.

38.

Griffin, J., Cohen, J. S., and Schecter, A. N. Assignment of

an Exchangeable Low
-
Field NH
Resonance of Ribonuclease A to the Active Site Histidine
-
119, Biochemistry.
12:

2096,
1973.



3


39.

Griffin, J. H., Cohen, J. S., and Schecter, A. N. Nuclear Magnetic Resonance Studies of a
Ribonuclease
-
Dincucleoside Phosphonate C
omplex and Their Implications for the
Mechanism of the Enzyme, Ann. NY Acad. Sci.
222:

693, 1973.

40.

Alazard, R., Cohen, P., Cohen, J. S., and Griffin, J. H. Interactions of Bovine Neurophysin
II with Oxytoxin and (8
-
Lysine) Vasopressin. High Resolution P
roton Nuclear Magnetic
Resonance Spectroscopy Studies, J. Biol. Chem.
249:

6895, 1974.

41.

Chaiken, I. M., Cohen, J. S., and Sokolski, E. Microenvironment of His 12 in Ribonuclease
S as Detected by
13
C NMR, J. Am. Chem. Soc.
96:

4703, 1974.

42.

Cohen, J. S
., Fisher, W., and Schecter, A. N. Spectroscopic Studies on the Conformation of
Cytochrome c and Apocytochrome, J. Biol. Chem.
249:

1113, 1974.

43.

Cohen, J. S., and B., H. M. Titration Curves of Histidine Ring Protons, V. Comparative
Study of Cytochrome c

from Three Species and the Assignment of Individual Proton
Resonances, J. Biol. Chem.
249:

5472, 1974.

44.

Quirt, A. R., Lyerla, J. R., Peat, I. R., Cohen, J. S., Reynolds, W. R., and Freedman, M. H.
Carbon
-
13 NMR Titration Shifts in Amino Acids, Nature.
96:

570, 1974.

45.

Wasylishen, R., and Cohen, J. S. Spin Lattice Relaxation Times of Imidazole Protons and
Their Relevance to NMR Studies of Proteins. Nature.
249:

847, 1974.

46.

Cohen, J. S., Bradley, R. B., and Clem, T. R. The pH
-

Dependence of the
13
C S
pin
-
Lattice
Relaxation Rate of the Carboxyl Carbon of Acetic Acid, J. Am. Chem. Soc.
97:

908, 1975.

47.

Cohen, J. S., and Shindo, H. NMR Titration Curves of Histidine Ring Protons VIII.
Conformational Change Affecting Three of the Histidine Residues of Rib
onuclease, J. Biol.
Chem.
250:

8874, 1975.

48.

Cohen, P., Camier, M., Alazard, R., Cohen, J. S., and Griffin, J. Studies of Bovine
Neurophysin
-
Neurophypophyseal Hormone Interactions, Ann. NY Acad. Sci.
248:

463,
1975.

49.

Griffin, J. H., Cohen, J. S., and
Cohen, P. Proton Magnetic Resonance Studies of Complex
Formation Between Bovine Neurophysins and Oxytocin, J. Pharm. Sci.
64:

507, 1975.

50.

Hayes, M. B., Hagenmaier, H., and Cohen, J. S. NMR Titration Curves of Histidine Ring
Protons. VII. Human Metmyoglo
bin and the Effects of Azide on Human, Horse and Sperm
Whale Metmyoglobins, J. Biol. Chem.
250:
, 1975.

51.

Matthews, C. R., Westmoreland, D., Hayes, M. B., and Cohen, J. S. NMR Titration Curves
of Histidine Ring Protons. VI. Effect of Temperature on Ribonu
clease A, J. Biol. Chem.
250:

7456, 1975.

52.

Yeh, H. C., Kirk, K. L., Cohen, L. A., and Cohen, J. S.
19
F and
1
H Nuclear Magnetic
Resonance Studies of Ring
-
Fluorinated Imidazoles and Histidines, J. Pharm. Soc., Perkin II
928, 1975.

53.

Matsuura, S., Niu, C
., and Cohen, J. S. Pyridium Polyhydrogen Fluoride, A Deprotecting
Reagent in Peptide Chemistry, Chem. Comm. 451, 1976.

54.

Shindo, H., and S., C. J. NMR Titration Curves of Histidine Ring Protons X. Ribonuclease
S
-
Peptide and S
-
Protein, J. Biol. Chem.
251
:

2648, 1976.

55.

Shindo, H., and Cohen, J. S. Observation of Individual Carboxyl Groups in Hen Egg White
Lysozyme Using High Field Carbon
-
13 Nuclear Magnetic Resonance, Proc. Natl. Acad.
Sci. USA.
73:

1979, 1976.

56.

Shindo, H., Hayes, M. B., and Cohen, J
. S. NMR Titration Curves of Histidine Ring Protons
IX. A Direct Assignment of the Resonances of the Active Site Histidine Residues of
Ribonuclease, J. Biol. Chem.
251:

2644, 1976.

57.

Egan, W., Liu, T.
-
Y., Dorow, S., Cohen, J. S., Robbins, J. D., Gotschli
ch, E. C., and
Robbins, J. B. Structural Studies of the Sialic Acid Polysaccharide Antigen of E. Coli Strain
Bos
-
12, Biochemistry.
16:

3687, 1977.



4


58.

Niu, C., Shindo, H., Gross, M., and Cohen, J. S. Characterization of the Acetyl
-
Chromotrpysin Intermediat
e by
13
C NMR Spectroscopy Intermediate by
13
C NMR
Spectroscopy, J. Am. Chem. Soc.
99:

3161, 1977.

59.

Shindo, H., Cohen, J. S., and Rupley, J. A. Self
-
Association of Hen Egg White Lysozyme
As Studied by Nuclear Magnetic Resonance, Biochemistry.
16:

3879, 1
977.

60.

Waysylishen, R. E., and Cohen, J. S. Influence of Copper(II) on Proton Nuclear Relaxation
Rates of Poly
-
L
-
Histidine, J. Am. Chem. Soc.
99:

2480, 1977.

61.

Egan, W., and Cohen, J. S. On the Tyrosine Residues of Ribonuclease, J. Biol. Chem.
253:

16,

1978.

62.

Schejter, A., Lanir, A., Vig, I., and Cohen, J. S. Direct Observation of the Methionine
Residues of Cytochrome c by Carbon
-
13 NMR Spectroscopy, J. Biol. Chem.
253:

3768,
1978.

63.

Shindo, H., Egan, W., and Cohen, J. S. Studies of Carboxyl Groups

in Proteins by Carbon
-
13 NMR Spectroscopy, J. Biol. Chem.
253:

6751, 1978.

64.

Ader, R., and Cohen, J. S. Relaxation Time Measurements of Bulk Water in Packed
Mammalian Density Dependent Cells Grown in Culture, J. Mag. Res.
34:

349, 1979.

65.

Granot, J.,
Elgavish, G., and Cohen, J. S. Phosphorus
-
31 Relaxation Times of Inorganic
Phosphate and Nucleotides in Aqueous Solution, J. Magn. Res.
33:

569, 1979.

66.

Niu, C., Bertrand, R., Shindo, H., and Cohen, J. S. Cross
-
Peptide Bond
13
C
-

15
N Coupling
Constants b
y
13
C and J Cross
-
Polarization
15
N NMR, J. Biochem. Biophys. Methods.
1:

135, 1979.

67.

Niu, C., Matsuura, S., Shindo, H., and Cohen, J. S. Specific Peptide
-
Protein Interactions in
the Ribonuclease S' System Studied by
13
C Nuclear Magnetic Resonance Spectr
oscopy with
Selectively
13
C Enriched Peptides, J. Biol. Chem.
254:

3788, 1979.

68.

Ohms, J. P., Hagenmaier, H., Hayes, M. B., and Cohen, J. S. The Near
-
heme Histidine
Residues of Deoxy
-

and Oxymyoglobins, Biochemistry.
18:

1599, 1979.

69.

Pollard, H., Shin
do, H., Cruetz, C., Pazoles, C., and Cohen, J. S. The State of ATP and the
Quantitation of Intragranular pH in Adrenergic Chromaffin Granules by
31
P Nuclear
Magnetic Resonance Spectroscopy, J. Biol. Chem.
254:

1170, 1979.

70.

Rosen, P., Pecht, L., and Cohe
n, J. S. Monitoring the Carbohydrate of the Fc Fragment of
Human IgG by
13
C NMR Spectroscopy, Mol. Immunol.
16:

435, 1979.

71.

Shindo, H., Matsuura, S., and Cohen, J. S. Conformation of Ribonuclease S
-
Protein,
Experientia.
35:

1284, 1979.

72.

Shindo, H., S
impson, R., and Cohen, J. S. An Alernating Conformation Characterizes the
Phosphodiester Backbone of Poly(dAdT) in Solution, J. Biol. Chem.
254:

8125, 1979.

73.

Wooten, J., and Cohen, J. S. Protein Mobility and Self
-
Association by Deuterium NMR,
Biochemist
ry.
18:

4188, 1979.

74.

Yariv, J., Cohen, J. S., Kalb (GIlboa), A. J., Jacobson, L., and Schecter, Y. Carbon
-
13 NMR
Analysis of Methionine Sulphoxide in Protein, J. Biochem. Biophys. Methods.
1:

145,
1979.

75.

Niu, C., Shindo, H., Matsuura, S., and Cohen,
J. S. Direct Observation of Peptide Exchange
by Stable Isotope Enrichment, J. Biol. Chem.
255:

2036, 1980.

76.

Shindo, H., McGhee, J., and Cohen, J. S.
31
P NMR Studies of DNA in Nucleosome Core
Particles, Biopolymers.
19:

523, 1980.

77.

Chen, C.
-
W., Cohen,

J. S., and Zador, A. Convenient Continuous Sonication Method for the
Preparation of Medium
-
Sized Polydeoxynucleotides, J. Biochem. Biophys. Methods.
5:
,
1981.

78.

Cohen, J. S., Wooten, J. B., and Chatterjee, C. L. Characterization of Alternating DNA
Confo
rmations in
31
P NMR Spectroscopy``, Biochemistry.
20:

3049, 1981.

79.

Jacobsen, L., and Cohen, J. S. Improved Technique for the Investigation of Cell
Metabolism, Biosci. Rep.
1:

141, 1981.



5


80.

Wooten, J. B., Cohen, J. S., Vig, I., and Schejter, A. The pH
-
I
nduced Conformational
Transitions of Ferricytochrome c: a
13
C and
1
H NMR Study, Biochemistry.
20:

5394, 1981.

81.

Zweier, J., Wooten, J. B., and Cohen, J. S. Studies of Anion Binding by Transferrin using
13
C NMR Spectroscopy, Biochemistry.
20:

3505, 1981.

82.

Chen, C.
-
W., Cohen, J. S., and Behe, M. The B to Z Transition of Double
-
Stranded
Poly(deoxyguanyl deoxycytidine) in Solution, Biochemistry.
22:

2136
-
2142, 1983.

83.

Chen, C.
-
W., and Cohen, J. S. Salt and Sequence Dependence of the Secondary Structure o
f
DNA in Solution by
31
P NMR Spectroscopy, Biopolymers.
22:

879
-
893, 1983.

84.

Chen, C.
-
W., Knop, R. H., and Cohen, J. S. Adriamycin Inhibits the B to Z Transition of
Poly(dGm5dc).poly(dGm5dC), Biochemistry.
22:

5468
-
5471, 1983.

85.

Foxall, D. L., and Cohe
n, J. S. NMR Studies of Perfused Cells, J. Mag. Res.
52:

346
-
349,
1983.

86.

Foxall, D. L., Cohen, J. S., and Tschudin, R. G. Selective Observation of
13
C Enriched
Metabolites by
1
H NMR, J. Magn. Res.
51:

330
-
334, 1983.

87.

Navon, G., Burrows, H., and Cohen
, J. S. Differences in Metabolite Levels Upon
Differentiation of Intact Neuroblastoma/Glioma Cells Observed by Proton NMR
Spectroscopy, FEBS Lett.
162:

320
-
323, 1983.

88.

Chen, C.
-
W., Cohen, J. S., Myers, C. E., and Sohn, M. Paramagnetic Metalloporphyrins
as
Potential Contrast Agents in NMR Imaging, FEBS Lett.
168:

70, 1984.

89.

Cohen, J. S., Chen, C. W., and Bax, A. Selective Observation of Phosphate Ester Protons by
1
H(
31
P) Spin Echo Different Spectroscopy, J. Magn. Res.
59:

181
-
187, 1984.

90.

Foxall, D.

L., Cohen, J. S., and Mitchell, J. B. Continuous Perfusion of Mammalian Cells
Embedded in Agarose Gel Threads, Exp. Cell Res.
154:

521
-
529, 1984.

91.

Howard, F. B., Chen, C.
-
W., Cohen, J. S., and Miles, H. T. Poly(d2NH
2
A.dT); Effects of 2
-
Amino Sustituent

on the B to Z Transition, Biochem. Biophys. Res. Commun.
118:

848
-
853, 1984.

92.

Hughes, L. T
., Cohen, J. S., Szabo, A., Niu
, C., and Matsuura, S.
13
C NMR Studies of the
Molecular Dynamics of Selectively
13
C Enriched Ribonuclease Complexes, Biochemistry.
23:

4390
-
4394, 1984.

93.

Knop, R., Chen, C.
-
W., Mitchell, J. B., Russo, A., and McPerson, S. C., J. S. Metabolic
Studies of Mammalian Cells by
31
P NMR Using a Continous Perfusion Technique,
Biochim. Biophys. Acta.
894:

275
-
284, 1984.

94.

Borah, B., Chen, C
., Egan, W., Miller, M., Wlodawer, A., and Cohen, J. S. NMR and
Neutron Diffraction Studies of the Complex of RNase with Uridine Vanadate, a Transition
State Analog, Biochemistry.
24:

2058
-
2967, 1985.

95.

Borah, B., Cohen, J. S., and Bax, A. Conformation o
f Double Stranded
Polydeoxynucleotides in Solution by Proton Two
-
Dimensional Nuclear Overhauser
Enhancement Spectroscopy, Biopolymers.
24:

747
-
765, 1985.

96.

Borah, B., Cohen, J. S., Howard, F. B., and Miles, H. T. Poly(d2NH2A.dT):
Characterization of the
High Salt Form by Two
-
Dimensional NMR Spectroscopy,
Biochemistry.
24:

7456
-
7462, 1985.

97.

Borah, B., Roy, S., Zon, G., and Cohen, J. S. Unique Pyrimidine 2D
-
COSY Aromatic
Cross
-
Peaks as Monitors of Pyrimidine Environments and Mobility in Oligo
-

and Poly
-
n
ucleotides, Biochem. Biophys. Res. Comm.
133:

380
-
388, 1985.

98.

Knop, R. H., Chen, C. W., Mitchell, J. B., Russo, A., McPherson, S., and Cohen, J. S.
Adaptive Cellular Response to Hyperthermia:
31
P
-
NMR Studies, Biochim. Biophys. Acta.
845:

171
-
177, 1985.

99.

Borah, B., Howard, F. B., Miles, T. M., and Cohen, J. S. Conversions of Poly(d2NH
2
A
-
dXU) from B to A Forms in High Salt an NMR and CD Study, Biochemistry.
25:

7464
-
7470, 1986.



6


100.

Cohen, J. S., Lyon, R. C., Chen, R. C., Faustino, P. J., Batist, G., Sh
oemaker, M.,
Rubalcaba, E., and Cowan, K. H. Differences in phosphate metabolite levels in drug
-
sensitive and
-
resistant human breast cancer cell lines determined by
31
P magnetic
resonance spectroscopy, Cancer Res.
46:

4087
-
4090, 1986.

101.

Lyon, R. C., Fa
ustino, P. J., and Cohen, J. S. A Perfusion Technique for
13
C NMR Studies
of the Metabolism of
13
C
-
Labeled Substrates by Mammalian Cells, Mag. Reson. Med.
3:

663
-
672, 1986.

102.

Patronas, N. J., Cohen, J. S., Knop, R. H., Dwyer, A. J., Colcher, D., Lundy,
J., Mornex, F.,
Hambright, P., Sohn, M., and Myers, C. E. Metalloporphyrin Contrast Agents for Magnetic
Resonance Imaging of Human Tumors in Mice, Cancer Treat. Rep.
70:

390, 1986.

103.

Roy, S., Hiyama, Y., Torchia, D., and Cohen, J. S. New Enzymatic Synth
esis of 2'
-
deoxynucleoside
-
2',2'
-
d
2

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.

Sterin M, Cohen J, and Ringel, I. Hormone sensitivity is reflected in the
phospholipid profile in breast cancer cells. Breast Cancer Res. & Treat.
87
: 1
-
11,
2004

188
.

Meidan, V., Glazer, J., Salomon, S., Sidi, Y., Barenho
lz, Y., Cohen, J. S., and
Lilling, G. Antisense Against Bcl
-
2 in Breast Cancer Cells: A Systematic
Comparison of Different Lipoplexes
,

J. Liposome Res.

16
:

27
-
43, 2006
.

189
.

Freikman,
I., Amer,

J,

Cohen
, J.S.,

Ringel,

I., and

Fibach
, E.
Oxidative stress causes
memb
rane phospholipid rearrangement
and shedding from RBC membranes
-

an
NMR study
. Biochem. Biophys. Acta
, 2008.





12


B
OOKS AND
C
HAPTERS
:

(books are in bold)


190
.

Blackburn, G. M., and Cohen, J. S. Chemical Oxidative Phosphorylation.
In:

Grayson and
Griffiths (
eds.), Topics in Phosphorus Chemistry, Vol. 6. New York: Wiley
-
Interscience,
1969.

191
.

Cohen, J. S. Nuclear Magnetic Resonance Investigations of Interactions of Biomolecules.
In:

C. Nicolau (ed.) Experimental Methods in Biophysical Chemistry, pp. 521
-
588. Lon
don:
Wiley & Sons, 1973.

192
.

Hayes, M. B., Cohen, J. S., and McNeel, N. L. NMR of Amino Acids, Peptides and Proteins,
Magnetic Resonance Reviews.
3:

3491
-
3496, 1974.

193
.

Egan, W., Liu, T.
-
Y., Cohen, J. S., and Robbins, J. B. Studies in Meningococcal
Polysacchari
des: Characterization of the Antigens from E Coli: Bos
-
12 by
13
C NMR
Spectroscopy.
In:

E. R. Klein and T. S. Klein (eds.), Proc. of the Second Intl. Conf. on Stable
Isotopes, pp. 728
-

733. Springfield, Va.: Natl. Tech. Information Services, 1976.

194
.

Egan, W.,

Shindo, H., and Cohen, J. S. Carbon
-
13 NMR Studies of Proteins, Ann. Rev.
Biophys. Bioeng.
6:

383
-
417, 1977.

195
.

Cohen, J. S. Nuclear Magnetic Resonance Studies of Biologically Relevant Isotopes Other
than Hydrogen, Crit. Rev. Biochem.
5:

25
-
43, 1978.

196
.

Portuga
l, F. H., and Cohen, J. S. A Century of DNA. Boston: MIT Press, 1978;
Paperback edition,1980 (with a Foreword by Lord Todd, President, Royal Society).

197
.

Cohen, J. S. (ed.) Magnetic Resonance in Biology, Vol. 1. New York: Wiley
-

Interscience, 1980.

198
.

Cohen, J.
S., Niu, C., Matsuura, S., and Shindo, H. Conformation, Mechanism, and Peptide
-
Exchange
by

13
C NMR Spectroscopy: Elsevier, 1980.

199
.

Cohen, J. S., and Chen, C. W.
31
P NMR Studies of DNA Conformation and Dynamics.
In:

G. Levy (ed.) New Methods and Applications
of NMR Spectroscopy, pp. 249
-
267.
Washington: ACS Monograph, 1982.

200
.

Cohen, J. S. (ed.) Non
-
Invasive Probes of Tissue Metabolism. New York: Wiley
-

Interscience, 1982.

201
.

Jacobsen, L., and Cohen, J. S. Intracellular pH Measurement by NMR Methods.
In:

J. S.
Cohen

(ed.) Noninvasive Probes of Tissue Metabolism, pp. 5
-
16: Wiley
-
Interscience, 1982.

202
.

Wooten, J. B., Cohen, J. S., and Schejter, A. Conformational Transitions of Fericytochrome
c Studied by
13
C and
1
H NMR Spectroscopy.
In:

C. Ho and W. Eaton (eds.), Interact
ions
Between Iron and Proteins in Oxygen and Electron Transport, pp. 43
-
49. NY: Elsevier, 1982.

203
.

Cohen, J. S. (ed.) Magnetic Resonance in Biology, Vol. 2. New York: Wiley
-

Interscience, 1983.

204
.

Cohen, J. S., Chen, C. W., and Knop, R. Secondary Structure of DN
A in Solution by NMR
Methods.
In:

Nucleic Acids: Vectors of Life, Proceedings of the 16th Jerusalem Symposium
on Quantum Chemistry and Biochemistry", 1983, pp. 127
-
139.

205
.

Cohen, J. S., Hughes, L., and Wooten, J. B. Observations of Amino Acid Side Chains in
P
roteins by NMR Methods.
In:

J. S. Cohen (ed.) Mag. Res. Biol., Vol. 2, 1983.

206
.

Cohen, J. S., Knop, R., Navon, G., and Foxhall, D. L. NMR in Biology and Medicine.
In:

J.
V. Bannister and A. M. Michelson (eds.), Life Chemistry Reports, pp. 281
-
457. London:
Har
dwood, 1983.

207
.

Chen, C. W., and Cohen, J. S.
31
P NMR Studies of Polydeoxynucleotides.
In:

D. Gorenstein
(ed.)
31
P NMR Spectroscopy, pp. 233
-
263: Academic Press, 1984.

208
.

Cohen, J. S.
In:

T. Govil, C. L. Khetrapal, and A. Saran (eds.), Magnetic Resonance in
Biol
ogy and Medicine, pp. 77
-
100. New Dehli, India: Tata
-
McGraw Hill, 1985.



13


209
.

Cohen, J. S., and Lyon, R. C. Metabolism of Perfused Drug
-
Sensitive and Resistant Breast
Cancer Cells.
In:

S. McCarthy and F. Haseltine (eds.), Magnetic Resonance of the
Reproductive S
ystem, pp. 51
-
66. NY: Slack, 1986.

210
.

Cohen, J. S., and Lyon, R. C. Metalloporphyrins as Potential Contrast Agents in MRI.
Contrast Agents in MRI, pp. 35
-
40: Excerpta Medica, 1986.

211
.

Cohen, J. S. Phospholipid and Energy Metabolism of Cancer Cells Monitored by
3
1
P
Magnetic Resonance Spectroscopy: Possible Clinical Significance, Mayo Clin. Proc.
48:

1199
-
1207, 1988.

212
.

Lyon, R. C., Daly, P. F., and Cohen, J. S. Effects of Drugs on the Metabolism of Human
Cancer Cells in Vitro and Implanted in Mice Monitored by Magnet
ic Resonance
Spectroscopy.
In:

J. W. Jaroszewski, J. Schaumberg, and M. Kofod (eds.), NMR
Spectroscopy and Drug Development, pp. 508
-
529. Copenhagen: Benzon Fndtn. Symp, No.
26, 1988.

213
.

Stein, C. A., and Cohen, J. S. Oligodeoxynucleotides as Inhibitors of Ge
ne Expression: a
Review, Cancer Res.
48:

2659
-
2668, 1988.

214
.

Cohen, J. S.

(ed)

Oligodeoxynucleotides: Antisens
e Inhibitors of Gene Expression
:
Macmillan

Press,
London
1989.

215
.

Cohen, J. S., Lyon, R. C., and Daly, P. F. Monitoring Intracellular Metabolism by NMR,

Methods Enzymol.
177:

435
-
438, 1989.

216
.

Daly, P., and Cohen, J. S. Magnetic Resonance Spectroscopy of Tumors and Potential In
Vivo Clinical Applications: a Review, Cancer Res.
49:

770
-
779, 1989.

217
.

Stein, C. A., and Cohen, J. S. Antisense Compounds: Potential

Role in Cancer Therapy.
In:

V. T. DeVita, S. Hellman, and S. A. Rosenberg (eds.), Important Advances in Oncology, pp.
79
-
97. NY: Lippincott, 1989.

218
.

Stein, C. A., and Cohen, J. S. Phosphorothioate Oligodeoxynucleotide Analogs.
In:

J. S.
Cohen (ed.) Oligodeo
xynucleotides: Antisense Inhibitors of Gene Expression, pp. 97
-
117.
Boca Raton, Fl: CRC Press, 1989.

219
.

Cohen, J. S. Antisense oligonucleotides as an approach towards anti
-
AIDS therapy.
In:

E.
DeClerq (ed.) Design of Anti
-
AIDS Drugs, Vol. 14. New York: Elsevi
er, 1990.

220
.

Cohen, J. S. Antisense oligodeoxynucleotides as antiviral agents, Antiviral Res.
16:

121
-
133,
1991.

221
.

Cohen, J. S. Antisense Compounds.
In:

V. T. DeVita, S. Hellman, and S. A. Rosenberg
(eds.), Biologic The
rapy of Cancer, pp. 763
-
775. NY
: Lippincot
t, 1991.

222
.

Cohen, J. S. Antisense oligonucleotides as anti
-
viral agents: new drugs for a new age.
In:

L.
M. de la Maza and E. M. Peterson (eds.), Medical Virology, Vol. 10. New York: Plenum
Publishing, 1991.

223
.

Cohen, J. S. Oligonucleotides as therapeutic agen
t
s,
Pharmacol. Therap.
52:

211
-
225, 1991.

224
.

Jaroszewski, J. W., and Cohen, J. S. Cellular Uptake of Antisense Oligodeoxynucletides.
In:

R. L. Juliano (ed.) Advanced Drug Delivery Reviews, pp. 235
-
250, 1991.

225
.

Cohen, J. S. Chemically Modified Oligodeoxynucleoti
de Analogs as Regulators of Viral and
Cellular Gene Expression.
In:

R. P. Erickson and J. Izant (eds.), Gene Regulation by
Antisense Nucleic Acids, pp. 247
-
259. NY: Raven Press, 1992.

226
.

Cohen, J. S. Informational drugs: a new concept in pharmacology. In: P.
Krogsgard
-

Larsen
and M. Kofod (eds.), New Leads, and Targets in Drug Research, Vol. 33, pp. 17
-
32.
Copenhagen: Benzon Fndtn. Symp., 1992.

227
.

Cohen, J. S. Oligonucleotide therapeutics, Trends Biochem. Sci.
10:

87
-
91, 1992.

228
.

Cohen, J. S. Phosphorothioate oligod
eoxynucleotides. In: S. Crooke and B. Lebleu (eds.),
Antisense Research and Applications, pp. 205
-
221. Boca Raton, FL: CRC Press, 1992.

229
.

Cohen, J. S. Selective anti
-
gene therapy for cancer: principles and prospects, Tohuku J. Exp.
Med.
168:

351
-
359, 1992.



14


230
.

G
hosh, M., and Cohen, J. S. Oligodeoxynucleotides as antisense inhibitors of gene
expression, Prog. Nucl. Acids Res. Molec. Biol.
42:

79
-
126, 1992.

231
.

Kaplan, O., van Zijl, P. C. M., and Cohen, J. S. NMR Studies of Metabolism of Cells and
Perfused Organs.
In:

J. Seelig and M. Rudin (eds.), In
-
Vivo Magnetic Resonance
Spectroscopy III: Potential and Limitations. Heidelberg: Springer
-
Verlag, 1992.

232
.

Ruiz
-
Cabello, J., and Cohen, J. S. NMR and the study of pathological state in cells and
tissues, Intl. Rev. Cytology.
145:

1
-
63, 1992.

233
.

Ruiz
-
Cabello, J., and Cohen, J.S. Phospholipid metabolism as indicators of cancer cell
function, NMR Biomed.
5:

226
-
233, 1992.

234
.

Cohen, J. S. De strategie de antisense.
In:

H. Schellekens (ed.) 'DNA', pp. 43
-
55.
Amsterdam: Natuur & Techniek,

1993 (also English and German eds.).

235
.

Cohen, J. S. Towards a new chemotherapy: oligonucleotide analogs as informational drugs.
In:

B. Huber (ed.) Cancer Therapy into the Twenty
-
First Century, pp. 145
-
162, 1994.

236
.

Cohen, J. S. Gene
-
mimetic substances: drugs d
esigned to intervene in gene expression, Adv.
Pharm.
25:

319
-
339, 1994.

237
.

Cohen, J. S., and Hogan, M. The new genetic medicines, Scientific American.
271 (6):

50
-
55, 1994.

238
.

Jaroszewski, J., Roy, S., and Cohen, J. S. Nuclear magnetic resonance studies of oligo
-
nucleotides.
In:

S. Agrawal (ed.) Methods in Molecular Biology, Vol. 26, pp. 301
-
317. NY:
Humana Press, 1994.

239
.

Kaplan, O., and Cohen, J. S. Metabolism of breast cancer cells as revealed by non
-
invasive
magnetic resonance spectroscopy studies, Breast Cancer

Res. & Treat.
31:

285
-
299, 1994.

240
.

Kaplan, O., and Cohen, J. S. Lymphocyte activation
-

31
P magnetic resonance studies of
energy metabolism and phospholipid pathways, Immunomethods.
4:

139
-
147, 1994.

241
.

Cohen, J. S., Jaroszewski, J., Kaplan, O., Ruiz
-
Cabello,
J., and Collier, S. A History of
Biological Magnetic Resonance.
In:

J. W. Emsley and J. Feeney (eds.), Progr. Magn. Reson.
Spect. (50th ann. ed. of discovery of NMR), Vol. 28, pp. 53
-
86. London: Elsevier, 1995.

242
.

Mercola, D., and Cohen, J. S. Antisense appro
aches to cancer gene therapy, Cancer Gene
Therapy.
2:

47
-
59, 1995.

243
.

Mardor, Y., and Cohen, J. S. Primer on Magnetic Resonance Methods: MRI and MRS, in
Encyclopedia of Cancer, Vol. 2. San Diego: Academic Press, 2002.

244
.

Cohen J.S. (co
-
ed) Encyclopedia of Cancer
, Vol. 2. San Diego: Academic Press, 2002

245
.

Cohen, J.S.
Biomedical Applications of Diffusion Weighted NMR Techniques. Israel J.
Chem.
, in press
, 2003.





15


N
ON
-
R
ESEARCH
P
UBLICATIONS
:


245
.

Cohen, J. S. Scientific and Technological Relations, Hearings on Detente bef
ore the Sub
-
Committee on Europe of the House Foreign Affairs Committee.
In:

Testimony given on
behalf of the Committee of Concerned Scientists June, 1974.

246
.

Cohen, J. S., and Portugal, F. The Search for the Chemical Structure of DNA, Conn. Med.
38:

551
-
557,
1974.

247
.

Portugal, F., and Cohen, J. S. On the Origins of Molecular Biology, Nature.
250:

791, 1974.

248
.

Cohen, J. S., and F., P. A Comment on Historical Analysis in Biochemistry, Perspect. Biol.
& Med.
18:

204
-
207, 1975.

249
.

Cohen, J. S. Scientific Societies & Scien
tists' Rights, Fed. Proc.
37:

1991, 1978.

250
.

Cohen, J. S. Limits still tight on Soviet scientists (Book Review of 'Soviet Science' by
Zhores Medvedev), Chem. & Eng. News p. 46, 1979.

251
.

Cohen, J. S. DNA: Is the Backbone Boring?, Trends Biochem. Sci.
5:

58
-
60, 19
80.

252
.

Cohen, J. S. NMR and Biochemistry (Book Review), Anal. Biochem.
107:

236, 1980.

253
.

Cohen, J. S. Duel in the Laboratory (Book Review of 'The Nobel Duel,' by A. Wade), Chem.
& Eng. News p. 48., 1981.

254
.

Baltimore, D., et al. Degrees revoked in Soviet Union, Sc
ience.
216:

360, 1982.

255
.

Cohen, J. S., and Wlodawer, A. Diffraction and NMR Studies of Proteins; an Uneasy
Alliance, Trends Biochem. Sci.
7:

389
-
391, 1982.

256
.

Cohen, J. S. Important Compendium on Molecular Biology (Book Review of 'Structural
Molecular Biology,
Davies, D.B., et al., eds.), Trends Biochem. Sci.
8:

387, 1983.

257
.

Cohen, J. S. 2D
-
NOESY of DNA: As easy as A, B, Z, Trends Biochem. Sci.
12:

133, 1987.

258
.

Cohen, J. S. Designing antisense oligonucleotides as pharmaceutical agents, Trends
Pharmacol. Sci.
10:

435
-
437, 1989.

259
.

Rothenberg, M., Johnson G., Laughlin, C., Green, L., Cradock, J., Sarver, N., and Cohen,
J.S. Oligodeoxynucleotides as antisense inhibitors of gene expression: therapeutic
implications, JNCI.
81:

1539, 1989.

260
.

Kaplan, O., and Cohen, J. S. Mag
netic resonance as a non
-
invasive tool to study metabolism
in pharmacological research, Trends Pharmacol. Sci.
11:

398
-
400, 1990.

261
.

Cohen, J. S. Informational drugs: a new concept in pharmacology, Antisense Res. Dev.
1:

191
-
193, 1991.

262
.

Cohen, J. S. The NIH in
tramural program, Science.
262:

489
-
490, 1993.

263
.

Cohen, J. S. Genetic Drugs, promise and prospects, Drug News and Perspectives.
7:

340
-
343, 1994.