Genetic Engineering Study Guide Notes: Karyotyping / Gen. Disorders, Pedigree webquest , Manipulating DNA, Selective Breeding

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Name: _____________________________

Genetic Engineering Study Guide

Notes: Karyotyping/ Gen. Disorders, Pedigree webquest, Manipulating DNA, Selective Breeding.


1.

What is the purpose of selective breeding? Give an example.




2.

What is one disadvantage
of inbreeding (why is it discouraged)?




3.

What is the purpose of hybridization?



a.

Give an example
of a hybrid organism
.



4.

What is genetic engineering?



a.

What is a disadvantage or ethical issue with genetically modifying organisms?




5.

What is recombinant
DNA?



6.

What is the purpose of gel electrophoresis?




7.

What is a clone?


a.

List the steps it took to clone Mimi the mouse

or Dolly the sheep
.





8.

How many chromosomes does the normal human have? _______

a.

What would my sex chromosomes be if I were female? __
____

b.

If I were male? ________

c.

Has anyone ever been born without an X chromosome? ______

d.

Where are most sex
-
linked genes found? _______________

9.

What is the purpose of a karyotype?


a.

List 3

things
a karyotype show
s
?


b.

What does homologous chromosomes mean?


10.

Human gametes
contain ______ autosomes and ______ sex chromosomes each.


11.


In pedigr
ees, males are drawn as a __
__
_
____ and females are drawn as a ____
__
___.

a.

How would you show someone is a carrier?

b.

Make sure that you can draw a pedigree if given a
scenario
.



12.


What is nondisjunction?


a.

Which chromosomes does nondisjunction affect?


13.

Match the following disease or disorders to their definitions.

_____ 1. Huntington

A. Sex
-
linked disorder where individuals do not
produce the protein they need to
clot.

_____ 2. PKU (Phenylketonuria)


_____ 3. Tay Sachs


_____ 4. Sickle Cell Anemia

B
. Nondisjunction of chromosome 21. Causes
trisomy (3 copies) to be present.

_____ 5. Down Syndrome

C
. XXY


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_____‶K

Turner’s Syndrome

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